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    Academic Journals

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• Low knowledge of newborn danger signs among pregnant women in Papua New Guinea and implications for health seeking behaviour in early infancy - findings from a longitudinal study.

  Authors:Donya Eghrari, Michelle J. L. Scoullar, Alyce N. Wilson, Elizabeth Peach, Arthur Elijah, Pele Melepia, et al.From:BMC Pregnancy and Childbirth (Vol. 23, Issue 1) Peer-Reviewed

  Jan. 26, 20234,848 words Clinical report 1650LBackground Globally, 2.5 million babies die in the first 28 days of life each year with most of these deaths occurring in low- and middle-income countries. Early recognition of newborn danger signs is important in...

• The Medicines for Malaria Venture Malaria Box contains inhibitors of protein secretion in Plasmodium falciparum blood stage parasites.

  Authors:Oliver Looker, Dansline G., Hayley E. Bullen, Brad E. Sleebs, Brendan S. Crabb, and Paul R. GilsonFrom:Traffic (Vol. 23, Issue 9) Peer-Reviewed

  Sept. 20221,073 words Report

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• The impact of three progressively introduced interventions on second wave daily COVID-19 case numbers in Melbourne, Australia.

  Authors:Allan Saul, Nick Scott, Tim Spelman, Brendan S. Crabb, and Margaret HellardFrom:BMC Infectious Diseases (Vol. 22, Issue 1) Peer-Reviewed

  June 2, 20226,421 words Report 1580LBackground The city of Melbourne, Australia experienced two waves of the COVID-19 epidemic peaking, the first in March and a more substantial wave in July 2020. During the second wave, a series of control measure were...

• The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture.

  Authors:Hayley E. Bullen, Paul R. Sanders, Dansline G., Thorey K. Jonsdottir, David T. Riglar, Oliver Looker, et al.From:Molecular Microbiology (Vol. 117, Issue 5) Peer-Reviewed

  May 2022288 words Report, Brief articl...

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• Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of Plasmodium falciparum reveals several inhibitory compounds.

  Authors:Madeline G. Dans, Greta E. Weiss, Danny W. Wilson, Brad E. Sleebs, Brendan S. Crabb, Tania F. de Koning-Ward, et al.From:International Journal for Parasitology (Vol. 50, Issue 3) Peer-Reviewed

  Mar. 2020477 words Report

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• [CD8.sup.+] T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria

  Authors:Lei Shong Lau, Daniel Fernandez-Ruiz, Vanessa Mollard, Angelika Sturm, Michelle A. Neller, Anton Cozijnsen, et al.From:PLoS Pathogens (Vol. 10, Issue 5) Peer-Reviewed

  May 20149,982 words Report 1610LTo follow the fate of [CD8.sup.+] T cells responsive to Plasmodium berghei ANKA (PbA) infection, we generated an MHC I- restricted TCR transgenic mouse line against this pathogen. T cells from this line, termed PbT-I T...

• A model for the progression of receptor-ligand interactions during erythrocyte invasion by Plasmodium falciparum

  Authors:Katherine L. Harvey, Paul R. Gilson, and Brendan S. CrabbFrom:International Journal for Parasitology (Vol. 42, Issue 6) Peer-Reviewed

  May 15, 2012 Report

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• Development of fluorescent Plasmodium falciparum for in vitro growth inhibition assays

  Authors:Danny W. Wilson, Brendan S. Crabb, and James G. BeesonFrom:Malaria Journal (Vol. 9) Peer-Reviewed

  June 3, 20108,046 words Report Background Plasmodium falciparum in vitro growth inhibition assays are widely used to evaluate and quantify the functional activity of acquired and vaccine-induced antibodies and the anti-malarial activity of known...

• Functional genomics: identifying drug targets for parasitic diseases

  Authors:Alan F. Cowman and Brendan S. CrabbFrom:Trends in Parasitology (Vol. 19, Issue 11) Peer-Reviewed

  Nov. 2003134 words Article

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• A newly discovered protein export machine in malaria parasites

  Authors:Tania F. de Koning-Ward, Paul R. Gilson, Justin A. Boddey, Melanie Rug, Brian J. Smith, Anthony T. Papenfuss, et al.From:Nature (Vol. 459, Issue 7249) Peer-Reviewed

  June 18, 20095,799 words Report 1490LSeveral hundred malaria parasite proteins are exported beyond an encasing vacuole and into the cytosol of the host erythrocyte, a process that is central to the virulence and viability of the causative Plasmodium...

• Perspectives: The missing pieces

  Authors:Brendan S. Crabb, James G. Beeson, Rogerio Amino, Robert Menard, Andy Waters, Elizabeth A. Winzeler, et al.From:Nature (Vol. 484, Issue 7395) Peer-Reviewed

  Apr. 26, 20121,856 words Article 1440LNine experts give their opinion on the 'known unknowns' in malaria research. Author(s): Brendan S. Crabb, James G. Beeson, Rogerio Amino, Robert Ménard, Andy Waters, Elizabeth A. Winzeler, Mats Wahlgren, David A....

• Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes

  Authors:Greta E. Weiss, Paul R. Gilson, Tana Taechalertpaisarn, Wai-Hong Tham, Nienke W.M. de Jong, Katherine L. Harvey, et al.From:PLoS Pathogens (Vol. 11, Issue 2) Peer-Reviewed

  Feb. 201511,416 words Report 1530LDuring blood stage Plasmodium falciparum infection, merozoites invade uninfected erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand binding events. Understanding each element in...

• Targeted gene disruption shows that knobs enable malaria-infected red cells to cytoadhere under physiological shear stress

  Authors:Brendan S. Crabb, Brian M. Cooke, John C. Reeder, Ross F. Waller, Sonia R. Caruana, Kathleen M. Davern, et al.From:Cell (Vol. 89, Issue 2) Peer-Reviewed

  Apr. 18, 199758 words Article

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• Why Australia needs a Medical Research Future Fund

  Authors:Anthony L. Cunningham, Teresa Anderson, Christine C. Bennett, Brendan S. Crabb, Gareth Goodier, Douglas Hilton, et al.From:The Medical Journal of Australia (Vol. 202, Issue 3) Peer-Reviewed

  Feb. 16, 201565 words Report

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• Host cell remodelling in malaria parasites: a new pool of potential drug targets

  Authors:Paul R. Gilson, Scott A. Chisholm, Brendan S. Crabb, and Tania F. de Koning-WardFrom:International Journal for Parasitology (Vol. 47, Issue 2) Peer-Reviewed

  Feb. 2017388 words Report

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• Insights and controversies into the role of the key apicomplexan invasion ligand, Apical Membrane Antigen 1

  Authors:Katherine L. Harvey, Alan Yap, Paul R. Gilson, Alan F. Cowman, and Brendan S. CrabbFrom:International Journal for Parasitology (Vol. 44, Issue 12) Peer-Reviewed

  Oct. 15, 201444 words Article

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• Protein export in malaria parasites: an update

  Authors:Brendan Elsworth, Brendan S. Crabb, and Paul R. GilsonFrom:Cellular Microbiology (Vol. 16, Issue 3) Peer-Reviewed

  Mar. 2014135 words Article

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• Biochemical and Functional Analysis of Two Plasmodium falciparum Blood-Stage 6-Cys Proteins: P12 and P41

  Authors:Tana Taechalertpaisarn, Cecile Crosnier, S. Josefin Bartholdson, Anthony N. Hodder, Jenny Thompson, Leyla Y. Bustamante, et al.From:PLoS ONE (Vol. 7, Issue 7) Peer-Reviewed

  July 27, 201211,078 words Article 1540LThe genomes of Plasmodium parasites that cause malaria in humans, other primates, birds, and rodents all encode multiple 6-cys proteins. Distinct 6-cys protein family members reside on the surface at each extracellular...

• The Plasmodium falciparum Erythrocyte Invasion Ligand Pfrh4 as a Target of Functional and Protective Human Antibodies against Malaria

  Authors:Linda Reiling, Jack S. Richards, Freya J. I. Fowkes, Danny W. Wilson, Watcharee Chokejindachai, Alyssa E. Barry, et al.From:PLoS ONE (Vol. 7, Issue 9) Peer-Reviewed

  Sept. 20, 20128,146 words Article 1460LAuthor(s): Linda Reiling 1 , 2 , Jack S. Richards 1 , 2 , 4 , Freya J. I. Fowkes 1 , 2 , 8 , Danny W. Wilson 2 , Watcharee Chokejindachai 3 , 9 , Alyssa E. Barry 2 , 1 , Wai-Hong Tham 2 , 4 , Janine Stubbs 1 , Christine...

• Broadly reactive antibodies specific for Plasmodium falciparum MSP-119 are associated with the protection of naturally exposed children against infection

  Authors:Arlene E Dent, Ann M Moormann, Christopher T Yohn, Rhonda J Kimmel, Peter O Sumba, John Vulule, et al.From:Malaria Journal (Vol. 11, Issue 1) Peer-Reviewed

  Aug. 21, 20128,528 words Report 1450LBackground The 19 kDa C-terminal region of Plasmodium falciparum Merozoite Surface Protein-1 is a known target of naturally acquired humoral immunity and a malaria vaccine candidate. MSP-1.sub.19 has four predominant...