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    Academic Journals

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• Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria

  Authors:Jo-Anne Chan, Damien R. Drew, Linda Reiling, Ashley Lisboa-Pinto, Bismarck Dinko, Colin J. Sutherland, et al.From:Frontiers in ImmunologyPeer-Reviewed

  Jan. 14, 2019294 words Brief article, Repor... 1560L

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• Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1

  Authors:Sheetij Dutta, Lisa S. Dlugosz, Damien R. Drew, Xiopeng Ge, Diouf Ababacar, Yazmin I. Rovira, et al.From:PLoS Pathogens (Vol. 9, Issue 12) Peer-Reviewed

  Dec. 201313,093 words Report 1520LMalaria vaccine candidate Apical Membrane Antigen-1 (AMA1) induces protection, but only against parasite strains that are closely related to the vaccine. Overcoming the AMA1 diversity problem will require an...

• Sex ratio adjustment and kin discrimination in malaria parasites

  Authors:Sarah E. Reece, Damien R. Drew, and Andy GardnerFrom:Nature (Vol. 453, Issue 7195) Peer-Reviewed

  May 29, 20085,846 words Report 1410LMalaria parasites and related Apicomplexans are the causative agents of the some of the most serious infectious diseases of humans, companion animals, livestock and wildlife. These parasites must undergo sexual...

• Defining the Antigenic Diversity of Plasmodium falciparum Apical Membrane Antigen 1 and the Requirements for a Multi-Allele Vaccine against Malaria

  Authors:Damien R. Drew, Anthony N. Hodder, Danny W. Wilson, Michael Foley, Ivo Mueller, Peter M. Siba, et al.From:PLoS ONE (Vol. 7, Issue 12) Peer-Reviewed

  Dec. 5, 20127,739 words Article 1490LAuthor(s): Damien R. Drew 1 , 2 , Anthony N. Hodder 2 , Danny W. Wilson 2 , Michael Foley 3 , Ivo Mueller 1 , 4 , Peter M. Siba 4 , Arlene E. Dent 5 , Alan F. Cowman 2 , James G. Beeson 1 , 2 , 6 , * Introduction...

• Functional Conservation of the AMA1 Host-Cell Invasion Ligand Between P. falciparum and P. vivax: A Novel Platform to Accelerate Vaccine and Drug Development

  Authors:Damien R Drew, Paul R Sanders, Gretchen Weiss, Paul R Gilson, and Brendan S CrabbFrom:Journal of Infectious Diseases (Vol. 217, Issue 3) Peer-Reviewed

  Feb. 1, 2018 Article

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• Structure--Activity Studies of [beta]-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1--RON2 Interaction

  Authors:Geqing Wang, Nyssa Drinkwater, Damien R. Drew, Christopher A. MacRaild, David K. Chalmers, Biswaranjan Mohanty, et al.From:Journal of Molecular Biology (Vol. 428, Issue 20) Peer-Reviewed

  Oct. 9, 2016533 words Report

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• PfRH5 as a candidate vaccine for Plasmodium falciparum malaria

  Authors:Damien R. Drew and James G. BeesonFrom:Trends in Parasitology (Vol. 31, Issue 3) Peer-Reviewed

  Mar. 201588 words Article

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• Chemotherapy, within-host ecology and the fitness of drug-resistant malaria parasites

  Authors:Silvie Huijben, William A. Nelson, Andrew R. Wargo, Derek G. Sim, Damien R. Drew, and Andrew F. ReadFrom:Evolution (Vol. 64, Issue 10) Peer-Reviewed

  Oct. 201076 words Report

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• Limited antigenic diversity of Plasmodium falciparumapical membrane antigen 1 supports the development of effective multi-allele vaccines

  Authors:Ulrich Terheggen, Damien R Drew, Anthony N Hodder, Nadia J Cross, Cleopatra K Mugyenyi, Alyssa E Barry, et al.From:BMC Medicine (Vol. 12, Issue 1) Peer-Reviewed

  Oct. 16, 201411,450 words Article 1480LAuthor(s): Ulrich Terheggen1,2 , Damien R Drew1 , Anthony N Hodder3 , Nadia J Cross1 , Cleopatra K Mugyenyi4 , Alyssa E Barry3,5 , Robin F Anders6 , Sheetij Dutta7 , Faith HA Osier4 , Salenna R Elliott1 , Nicolas...

• Induction and decay of functional complement-fixing antibodies by the RTS,S malaria vaccine in children, and a negative impact of malaria exposure

  Authors:Liriye Kurtovic, Paul A. Agius, Gaoqian Feng, Damien R. Drew, Itziar Ubillos, Jahit Sacarlal, et al.From:BMC Medicine (Vol. 17, Issue 1) Peer-Reviewed

  Feb. 25, 20199,028 words Report 1560LBackground Leading malaria vaccine, RTS,S, is based on the circumsporozoite protein (CSP) of sporozoites. RTS,S confers partial protection against malaria in children, but efficacy wanes relatively quickly after...

• Community-based molecular and serological surveillance of subclinical malaria in Myanmar.

  Authors:Katherine O'Flaherty, Win Han Oo, Sophie G. Zaloumis, Julia C. Cutts, Kyaw Zayar Aung, Myat Mon Thein, et al.From:BMC Medicine (Vol. 19, Issue 1) Peer-Reviewed

  May 28, 20216,851 words Report 1730LBackground In the Greater Mekong Subregion (GMS), current malaria surveillance strategies rely on a network of village health volunteers (VHVs) reporting the results of rapid diagnostic tests (RDTs), known to miss many...

• Novel Virus-Like Particle Vaccine Encoding the Circumsporozoite Protein of Plasmodium falciparum Is Immunogenic and Induces Functional Antibody Responses in Mice.

  Authors:Liriye Kurtovic, David Wetzel, Linda Reiling, Damien R. Drew, Catherine Palmer, Betty Kouskousis, et al.From:Frontiers in ImmunologyPeer-Reviewed

  Mar. 17, 2021315 words Brief article 1660L

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• Structure-Activity Studies of Truncated Latrunculin Analogues with Antimalarial Activity.

  Authors:Swapna Varghese, Raphaël Rahmani, Damien R. Drew, James G. Beeson, Jake Baum, Brian J. Smith, et al.From:ChemMedChem (Vol. 16, Issue 4) Peer-Reviewed

  Feb. 17, 2021233 words Report, Brief articl...

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• Malaria vaccine candidates displayed on novel virus-like particles are immunogenic and induce transmission-blocking activity

  Authors:Jo-Anne Chan, David Wetzel, Linda Reiling, Kazutoyo Miura, Damien R. Drew, Paul R. Gilson, et al.From:PLoS ONE (Vol. 14, Issue 9) Peer-Reviewed

  Sept. 10, 20196,665 words Report 1460LThe development of effective malaria vaccines remains a global health priority. Currently, the most advanced vaccine, known as RTS,S, has only shown modest efficacy in clinical trials. Thus, the development of more...

• Truncation of Plasmodium berghei merozoite surface protein 8 does not affect in vivo blood-stage development

  Authors:Tania F. De Koning-Ward, Damien R. Drew, Joanne M. Chesson, James G. Beeson, and Brendan S. CrabbFrom:Molecular & Biochemical Parasitology (Vol. 159, Issue 1) Peer-Reviewed

  May 2008222 words Article

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• A novel approach to identifying patterns of human invasion-inhibitory antibodies guides the design of malaria vaccines incorporating polymorphic antigens

  Authors:Damien R. Drew, Danny W. Wilson, Salenna R. Elliott, Nadia Cross, Ulrich Terheggen, Anthony N. Hodder, et al.From:BMC Medicine (Vol. 14, Issue 1) Peer-Reviewed

  Sept. 23, 20169,676 words Report 1600LBackground The polymorphic nature of many malaria vaccine candidates presents major challenges to achieving highly efficacious vaccines. Presently, there is very little knowledge on the prevalence and patterns of...