Search Results

• • 51 

    Academic Journals

  • Sort by: sorttype.publication.date.desc Newest sorttype.publication.date.asc Oldest sorttype.relevance Relevance

• The Medicines for Malaria Venture Malaria Box contains inhibitors of protein secretion in Plasmodium falciparum blood stage parasites.

  Authors:Oliver Looker, Dansline G., Hayley E. Bullen, Brad E. Sleebs, Brendan S. Crabb, and Paul R. GilsonFrom:Traffic (Vol. 23, Issue 9) Peer-Reviewed

  Sept. 20221,073 words Report

   Abstract Only

• The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture.

  Authors:Hayley E. Bullen, Paul R. Sanders, Dansline G., Thorey K. Jonsdottir, David T. Riglar, Oliver Looker, et al.From:Molecular Microbiology (Vol. 117, Issue 5) Peer-Reviewed

  May 2022288 words Report, Brief articl...

   Abstract Only

• Plasmodium species: master renovators of their host cells

  Authors:Tania F. de Koning-Ward, Matthew W.A. Dixon, Leann Tilley, and Paul R. GilsonFrom:Nature Reviews Microbiology (Vol. 14, Issue 8) Peer-Reviewed

  Aug. 201610,449 words Report 1430LPlasmodium parasites, the causative agents of malaria, have developed elaborate strategies that they use to survive and thrive within different intracellular environments. During the blood stage of infection, the...

• Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of Plasmodium falciparum reveals several inhibitory compounds.

  Authors:Madeline G. Dans, Greta E. Weiss, Danny W. Wilson, Brad E. Sleebs, Brendan S. Crabb, Tania F. de Koning-Ward, et al.From:International Journal for Parasitology (Vol. 50, Issue 3) Peer-Reviewed

  Mar. 2020477 words Report

   Abstract Only

• A model for the progression of receptor-ligand interactions during erythrocyte invasion by Plasmodium falciparum

  Authors:Katherine L. Harvey, Paul R. Gilson, and Brendan S. CrabbFrom:International Journal for Parasitology (Vol. 42, Issue 6) Peer-Reviewed

  May 15, 2012 Report

   Citation Only

• A newly discovered protein export machine in malaria parasites

  Authors:Tania F. de Koning-Ward, Paul R. Gilson, Justin A. Boddey, Melanie Rug, Brian J. Smith, Anthony T. Papenfuss, et al.From:Nature (Vol. 459, Issue 7249) Peer-Reviewed

  June 18, 20095,799 words Report 1490LSeveral hundred malaria parasite proteins are exported beyond an encasing vacuole and into the cytosol of the host erythrocyte, a process that is central to the virulence and viability of the causative Plasmodium...

• Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes

  Authors:Greta E. Weiss, Paul R. Gilson, Tana Taechalertpaisarn, Wai-Hong Tham, Nienke W.M. de Jong, Katherine L. Harvey, et al.From:PLoS Pathogens (Vol. 11, Issue 2) Peer-Reviewed

  Feb. 201511,416 words Report 1530LDuring blood stage Plasmodium falciparum infection, merozoites invade uninfected erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand binding events. Understanding each element in...

• Malaria Parasites Do the Stick-and-Slip Shuffle

  Author:Paul R. GilsonFrom:Cell Host & Microbe (Vol. 6, Issue 6)

  Dec. 17, 200968 words Report

   Abstract Only

• Host cell remodelling in malaria parasites: a new pool of potential drug targets

  Authors:Paul R. Gilson, Scott A. Chisholm, Brendan S. Crabb, and Tania F. de Koning-WardFrom:International Journal for Parasitology (Vol. 47, Issue 2) Peer-Reviewed

  Feb. 2017388 words Report

   Abstract Only

• Insights and controversies into the role of the key apicomplexan invasion ligand, Apical Membrane Antigen 1

  Authors:Katherine L. Harvey, Alan Yap, Paul R. Gilson, Alan F. Cowman, and Brendan S. CrabbFrom:International Journal for Parasitology (Vol. 44, Issue 12) Peer-Reviewed

  Oct. 15, 201444 words Article

   Abstract Only

• Protein export in malaria parasites: an update

  Authors:Brendan Elsworth, Brendan S. Crabb, and Paul R. GilsonFrom:Cellular Microbiology (Vol. 16, Issue 3) Peer-Reviewed

  Mar. 2014135 words Article

   Abstract Only

• Biochemical and Functional Analysis of Two Plasmodium falciparum Blood-Stage 6-Cys Proteins: P12 and P41

  Authors:Tana Taechalertpaisarn, Cecile Crosnier, S. Josefin Bartholdson, Anthony N. Hodder, Jenny Thompson, Leyla Y. Bustamante, et al.From:PLoS ONE (Vol. 7, Issue 7) Peer-Reviewed

  July 27, 201211,078 words Article 1540LThe genomes of Plasmodium parasites that cause malaria in humans, other primates, birds, and rodents all encode multiple 6-cys proteins. Distinct 6-cys protein family members reside on the surface at each extracellular...

• Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

  Authors:Natalie A Counihan, Scott A Chisholm, Hayley E Bullen, Anubhav Srivastava, Paul R Sanders, Thorey K Jonsdottir, et al.From:eLife (Vol. 6) Peer-Reviewed

  Mar. 2, 201718,193 words Article 1670LPlasmodium falciparum parasites, the causative agents of malaria, modify their host erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and for removal of toxic waste. Here we...

• Overlaying Molecular and Temporal Aspects of Malaria Parasite Invasion

  Authors:Greta E. Weiss, Brendan S. Crabb, and Paul R. GilsonFrom:Trends in Parasitology (Vol. 32, Issue 4) Peer-Reviewed

  Apr. 2016142 words Article

   Abstract Only

• Overlaying Molecular and Temporal Aspects of Malaria Parasite Invasion

  Authors:Greta E. Weiss, Brendan S. Crabb, and Paul R. GilsonFrom:Trends in Parasitology (Vol. 32, Issue 4) Peer-Reviewed

  Apr. 2016160 words Report

   Abstract Only

• Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum

  Authors:Danny W Wilson, Christopher D Goodman, Brad E Sleebs, Greta E Weiss, Nienke WM de Jong, Fiona Angrisano, et al.From:BMC Biology (Vol. 13, Issue 1) Peer-Reviewed

  July 18, 201511,388 words Article 1610LBackground Malaria invasion of red blood cells involves multiple parasite-specific targets that are easily accessible to inhibitory compounds, making it an attractive target for antimalarial development. However, no...

• The malaria PTEX component PTEX88 interacts most closely with HSP101 at the host-parasite interface

  Authors:Scott A. Chisholm, Ming Kalanon, Thomas Nebl, Paul R. Sanders, Kathryn M. Matthews, Benjamin K. Dickerman, et al.From:FEBS Journal (Vol. 285, Issue 11) Peer-Reviewed

  June 2018292 words Report

   Abstract Only

• Spatial organization of protein export in malaria parasite blood stages

  Authors:Sarah C. Charnaud, Thorey K. Jonsdottir, Paul R. Sanders, Hayley E. Bullen, Benjamin K. Dickerman, Betty Kouskousis, et al.From:Traffic (Vol. 19, Issue 8) Peer-Reviewed

  Aug. 20181,052 words Report

   Abstract Only

• The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites

  Authors:Sarah C. Charnaud, Matthew W. A. Dixon, Catherine Q. Nie, Lia Chappell, Paul R. Sanders, Thomas Nebl, et al.From:PLoS ONE (Vol. 12, Issue 7) Peer-Reviewed

  July 21, 201710,377 words Report 1600LMalaria is caused by five different Plasmodium spp. in humans each of which modifies the host erythrocyte to survive and replicate. The two main causes of malaria, P. falciparum and P. vivax, differ in their ability to...

• Functional Conservation of the AMA1 Host-Cell Invasion Ligand Between P. falciparum and P. vivax: A Novel Platform to Accelerate Vaccine and Drug Development

  Authors:Damien R Drew, Paul R Sanders, Gretchen Weiss, Paul R Gilson, and Brendan S CrabbFrom:Journal of Infectious Diseases (Vol. 217, Issue 3) Peer-Reviewed

  Feb. 1, 2018 Article

   Citation Only