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• Select Synthesis of 6,7-dimethoxy-1,3,4,8b-tetrahydroazirino [2,1-a]isoquinoline-N-borane and bis-(6,7-dimethoxy-1, 2,3,4-tetrahydroisoquinoline)-1,1-ene

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  Synthesis of 6,7-dimethoxy-1,3,4,8b-tetrahydroazirino [2,1-a]isoquinoline-N-borane and bis-(6,7-dimethoxy-1, 2,3,4-tetrahydroisoquinoline)-1,1-ene

  Authors:A. Sh. Saidov, K.K. Turgunov, B. Tashkhodzhaev, M.G. Levkovich, and V.I. VinogradovaFrom:Chemistry of Natural Compounds (Vol. 50, Issue 5) Peer-Reviewed

  Nov. 20142,288 words Article 1240LHomoveratrylamine was condensed with glycolic and oxalic acids in order to synthesize the corresponding amides. Their behavior in the Bischler--Napieralski reaction was studied. The structures of resulting...
• Select Syntheses based on norfluorocurarine. 5. NMR spectra of monomeric norfluorocurarine derivatives

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  Syntheses based on norfluorocurarine. 5. NMR spectra of monomeric norfluorocurarine derivatives

  Authors:M.G. Levkovich, P. Kh. Yuldashev, M.M. Mirzaeva, and B. TashkhodzhaevFrom:Chemistry of Natural Compounds (Vol. 48, Issue 3) Peer-Reviewed

  July 20124,209 words Article 1260LNMR spectra of norfluorocurarine and seven of its derivatives were studied. The NMR spectral parameters were related to stereochemical features using molecular modeling by the semi- empirical AM1 approximation. The...
• Select Crambain, a new alkaloid from plants of the genus crambe

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  Crambain, a new alkaloid from plants of the genus crambe

  Authors:I.I. Okhunov, M.G. Levkovich, and S.F. AripovaFrom:Chemistry of Natural Compounds (Vol. 49, Issue 2) Peer-Reviewed

  May 20131,258 words Article 1230LA new alkaloid called crambain was isolated from total alkaloids of two plant species of the genus Crambe, C. kotschyana Boiss. and C. orientalis L. (Cruciferae, mustard). The structure...
• Select Synthesis of 1-alkyltetrahydroisoquinolines

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  Synthesis of 1-alkyltetrahydroisoquinolines

  Authors:A.Sh. Saidov, M.G. Levkovich, and V.I. VinogradovaFrom:Chemistry of Natural Compounds (Vol. 49, Issue 5) Peer-Reviewed

  Nov. 20133,327 words Article 1410L1-Alkyltetrahydroisoquinolines were prepared by a Bischler-Napieralski reaction starting from homoveratrylamine and monobasic acids. Their structures were confirmed by IR and NMR spectral data. Keywords:...
• Select Synthesis of 1-Aryltetrahydroisoquinoline Alkaloids and their Analogs

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  Synthesis of 1-Aryltetrahydroisoquinoline Alkaloids and their Analogs

  Authors:Sh.N. Zhurakulov, V.I. Vinogradova, and M.G. LevkovichFrom:Chemistry of Natural Compounds (Vol. 49, Issue 1) Peer-Reviewed

  Mar. 20133,016 words Article 1380LThree alkaloids of the cryptostylin series and 20 monomolecular and 3 bimolecular 1-aryltetrahydroisoquinoline derivatives were prepared using the Picte-Spengler reaction. Keywords: 1-aryltetrahydroisoquinoline...
• Select Alkaloids from Crambe kotschyana endemic to Uzbekistan

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  Alkaloids from Crambe kotschyana endemic to Uzbekistan

  Authors:I.I. Okhunov, M.G. Levkovich, N.D. Abdullaev, V.U. Khuzhaev, and S.F. AripovaFrom:Chemistry of Natural Compounds (Vol. 47, Issue 3) Peer-Reviewed

  July 20111,527 words Article 1150LUDC 547.944/945 Plants of the genus Crambe (Cruciferae, mustard) are perennial herbs and number 12 species [1], four of which are encountered in Uzbekistan: C. kotschyana Boiss., C. edentula F., C. schugnana Korsh.,...
• Select Synthesis of bis-tetrahydroisoquinolines based on homoveratrylamine and a series of dibasic acids. 3

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  Synthesis of bis-tetrahydroisoquinolines based on homoveratrylamine and a series of dibasic acids. 3

  Authors:A. Sh. Saidov, E. Yu. Mazur, K.K. Turgunov, B. Tashkhodzhaev, M.G. Levkovich, and V.I. VinogradovaFrom:Chemistry of Natural Compounds (Vol. 50, Issue 3) Peer-Reviewed

  July 20144,532 words Article 1280LPyrido- and [1,4]-oxazinoisoquinolines, bis-tetrahydroisoquinolines, the alkaloid corydaldine, cleavage products, and a series of intermediates were prepared from homoveratrylamine and dibasic acids (glutaric and...
• Select Convolinine, a new alkaloid from Convolvulus subhirsutus of Uzbekistan flora

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  Convolinine, a new alkaloid from Convolvulus subhirsutus of Uzbekistan flora

  Authors:A.M. Gapparov, S.F. Aripova, B. Tashkhodzhaev, M.G. Levkovich, and O. AripovFrom:Chemistry of Natural Compounds (Vol. 46, Issue 4) Peer-Reviewed

  Sept. 20101,286 words Article 1190LSeveral alkaloids of known structure and the new base convolinine were isolated from total alkaloids from the aerial part of Convolvulis subhirsutus growing in Uzbekistan. It has been established that convolinine is an...
• Select A new melampolide and other secondary metabolites from Artemisia baldshuanica

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  A new melampolide and other secondary metabolites from Artemisia baldshuanica

  Authors:R.F. Mukhamatkhanova, I.D. Sham'yanov, S. Kh. Zakirov, B. Tashkhodzhaev, M.G. Levkovich, and N.D. AbdullaevFrom:Chemistry of Natural Compounds (Vol. 47, Issue 5) Peer-Reviewed

  Nov. 20112,011 words Article 1210LThe composition of secondary metabolites in benzene and alcohol extracts of the epigeal part of Artemisia baldshuanica Krasch. et Zarp. (Asteraceae) collected during the vegetative phase was investigated. A new...
• Select Synthesis of bis-tetrahydroiso uinolines based on homoveratrylamine and dibasic acids. 2

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  Synthesis of bis-tetrahydroiso uinolines based on homoveratrylamine and dibasic acids. 2

  Authors:A. Sh. Saidov, M.G. Levkovich, M. Alimova, and V.I. VinogradovaFrom:Chemistry of Natural Compounds (Vol. 49, Issue 6) Peer-Reviewed

  Jan. 20143,343 words Article 1400LBis-tetrahydroisoquinolines were prepared from homoveratrylamine andphthalic acids using a Bischler-Napieralski reaction. Their structures were confirmed by IR and NMR spectral data. Keywords: Bischler-Napieralski...
• Select Sesquiterpene lactones and new diterpenoid alkaloids from Artemisia korshinskyi

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  Sesquiterpene lactones and new diterpenoid alkaloids from Artemisia korshinskyi

  Authors:I.D. Sham'yanov, B. Tashkhodzhaev, R.F. Mukhamatkhanova, M.N. Sultankhodzhaev, M.G. Levkovich, N.D. Abdullaev, et al.From:Chemistry of Natural Compounds (Vol. 48, Issue 4) Peer-Reviewed

  Sept. 20123,313 words Article 1430LNew diterpenoid alkaloids that were called artekorine (1) and 6-ketoartekorine (2) and had the structures 1[alpha],14[alpha],16[beta]-trimethoxy-4[beta]-N-acetylanthroyloxy-6[beta],8[beta]-dihydroxy-N-ethylaconitane (1)...
• Select Synthesis of hydroxyethyl derivatives of 1-aryltetrahydroisoquinoline alkaloids

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  Synthesis of hydroxyethyl derivatives of 1-aryltetrahydroisoquinoline alkaloids

  Authors:Sh. N. Zhurakulov, M.G. Levkovich, and V.I. VinogradovaFrom:Chemistry of Natural Compounds (Vol. 49, Issue 6) Peer-Reviewed

  Jan. 20142,518 words Article 1600LNew hydroxyethyl derivatives of 1-aryltetrahydroisoquinoline alkaloids and diisoquinoline were prepared using a Pictet-Spengler reaction. Keywords: Pictet-Spengler reaction, hydroxyethyl derivatives of...
• Select New flavanone and other constituents of Helichrysum arenarium indigenous to China

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  New flavanone and other constituents of Helichrysum arenarium indigenous to China

  Authors:F. Yong, H.A. Aisa, R.F. Mukhamatkhanova, I.D. Sham'yanov, and M.G. LevkovichFrom:Chemistry of Natural Compounds (Vol. 46, Issue 6) Peer-Reviewed

  Jan. 20112,404 words Article 1460LA new flavonoid for which the structure (2S)-5,8,4'-trihydroxy-6,7- vinylenedioxyflavanone was established and the known compounds stigmasterol, stigmasterol [beta]-D-glucopyranoside, caffeic acid ethyl ester, and...
• Select Synthesis of 8-amino- and 8-acetyl(benzoyl) aminomackinazolinones and their condensation with aldehydes

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  Synthesis of 8-amino- and 8-acetyl(benzoyl) aminomackinazolinones and their condensation with aldehydes

  Authors:A.Sh. Abdurazakov, B.Zh. Elmuradov, I.S. Ortikov, M.G. Levkovich, and Kh.M. ShakhidoyatovFrom:Chemistry of Natural Compounds (Vol. 49, Issue 2) Peer-Reviewed

  May 20133,963 words Article 1550LMethods for preparing of 8-nitro- and 8-aminomackinazolinones were improved. 8-Acetyl(benzoyl)aminomackinazolinones reacted smoothly with aromatic aldehydes and furfurol in glacial acetic acid to give the corresponding...
• Select Reactivity and H-D exchange rate of the [alpha]-methylene of deoxyvasicinone and its homologs

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  Reactivity and H-D exchange rate of the [alpha]-methylene of deoxyvasicinone and its homologs

  Authors:Kh. M. Shakhidoyatov, M.G. Levkovich, B. Zh. Elmuradov, and N.D. AbdullaevFrom:Chemistry of Natural Compounds (Vol. 50, Issue 6) Peer-Reviewed

  Dec. 20142,969 words Article 1410LThe deuterium exchange rate of the [alpha]-methylene of deoxyvasicinone (1) and mackinazolinone (2) and their seven- (3) and eight-membered (4) homologs was studied in neutral, acidic, and basic media. It was found that...
• Select Synthesis of bis-tetrahydroisoquinolines based on homoveratrylamine and a series of dibasic acids. 1

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  Synthesis of bis-tetrahydroisoquinolines based on homoveratrylamine and a series of dibasic acids. 1

  Authors:A.Sh. Saidov, M. Alimova, M.G. Levkovich, and V.I. VinogradovaFrom:Chemistry of Natural Compounds (Vol. 49, Issue 2) Peer-Reviewed

  May 20131,508 words Article 1300LBis-tetrahydroisoquinolines were prepared starting from homoveratrylamine and dicarboxylic acids using the Bischler-Napieralski reaction. Their structures were confirmed using IR and NMR spectral data. Keywords:...
• Select Z- and E-conformers of N-chloroacetylcytisine

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  Z- and E-conformers of N-chloroacetylcytisine

  Authors:T.F. Ibragimov, M.G. Levkovich, V.A. Saprykina, and Kh. M. ShakhidoyatovFrom:Chemistry of Natural Compounds (Vol. 46, Issue 5) Peer-Reviewed

  Nov. 20101,944 words Article 1210LN-Chloroacetylcytisine was synthesized by acylation of (-)-cytisine. Stable Z- and E-conformers with respect to rotational isomerism around the N-12-CO bond were found in PMR spectra at room temperature. The point at...
• Select Syntheses based on norfluorocurarine. 4. Reactions with hydroxylamine

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  Syntheses based on norfluorocurarine. 4. Reactions with hydroxylamine

  Authors:M.M. Mirzaeva, B. Tashkhodzhaev, M.G. Levkovich, A.G. Eshimbetov, P. Kh. Yuldashev, and N.D. AbdullaevFrom:Chemistry of Natural Compounds (Vol. 48, Issue 1) Peer-Reviewed

  Mar. 20121,699 words Article 1240LTransformation products of the alkaloid (-)-norfluorocurarine with hydroxylamine were studied. The oxime of norfluorocurarine was obtained and converted by treatment with EtOH into 2-hydroxy-16-cyano- 2,16-...
• Select Synthesis of bis-Tetrahydroisoquinolines Based on Homoveratrylamine and Several Dibasic Acids. 4. Reaction with Malonic and Succinic Acids

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  Synthesis of bis-Tetrahydroisoquinolines Based on Homoveratrylamine and Several Dibasic Acids. 4. Reaction with Malonic and Succinic Acids

  Authors:A. Sh. Saidov, K. K. Turgunov, M. G. Levkovich, and V. I. VinogradovaFrom:Chemistry of Natural Compounds (Vol. 51, Issue 2) Peer-Reviewed

  Mar. 20152,867 words Article 1500LBischler-Napieralski cyclization of amides synthesized from homoveratrylamine and malonic and succinic acids produced N-(3,4-dimethoxy-[beta]-phenylethyl)-succinimide,...
• Select Synthesis of N-[2'-Bromo-4'-Methoxy-3'-([beta]-Cytisinylethoxy)Benzyl]Cytisine

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  Synthesis of N-[2'-Bromo-4'-Methoxy-3'-([beta]-Cytisinylethoxy)Benzyl]Cytisine

  Authors:Sh. B. Rakhimov, V. I. Vinogradova, and M. G. LevkovichFrom:Chemistry of Natural Compounds (Vol. 52, Issue 5) Peer-Reviewed

  Sept. 20161,276 words Article 1360LThe new cytisine derivatives N-(3'-[beta]-bromoethoxy-4'-methoxy-2'-bromobenzyl)cytisine and N-[2'-bromo-4'-methoxy-3'-([beta]-cytisinylethoxy)benzyl]cytisine were prepared from cytisine, substituted benzaldehyde, and...