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    Academic Journals

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• Select Synthesis and properties of 2?-Deoxy-2?,4?-difluoroarabinose-modified nucleic acids

  1

  Synthesis and properties of 2?-Deoxy-2?,4?-difluoroarabinose-modified nucleic acids

  Authors:Saul Martinez-Montero, Modesto Orozco, Guillem Portella, Tatiana Ilina, Petra Lindovska, Arden Dierker-Viik, et al.From:Journal of Organic Chemistry (Vol. 80, Issue 6) Peer-Reviewed

  Mar. 20, 201590 words Report

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• Select Efficient RNase H-directed cleavage of RNA promoted by antisense DNA or 2'F-ANA constructs containing acyclic nucleotide inserts

  2

  Efficient RNase H-directed cleavage of RNA promoted by antisense DNA or 2'F-ANA constructs containing acyclic nucleotide inserts

  Authors:Maria M. Mangos, Kyung-Lyum Min, Ekaterina Viazovkina, Annie Galarneau, Mohamed I. Elzagheid, Masad J. Damha, et al.From:Journal of the American Chemical Society (Vol. 125, Issue 3) Peer-Reviewed

  Jan. 22, 200347 words Article

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• Select A novel RNA motif based on the structure of unusually stable 2',5'-linked r(UUCG) loops

  3

  A novel RNA motif based on the structure of unusually stable 2',5'-linked r(UUCG) loops

  Authors:Alexei Yu Denisov, Rami N. Hannoush, Kalle Gehring, and Masad J. DamhaFrom:Journal of the American Chemical Society (Vol. 125, Issue 38) Peer-Reviewed

  Sept. 24, 200351 words Article

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• Select Frontispiece: Mechanochemical Synthesis of Short DNA Fragments.

  4

  Frontispiece: Mechanochemical Synthesis of Short DNA Fragments.

  Authors:James D. Thorpe, Daniel O'Reilly, Tomislav FriÅ¡Äic, and Masad J. DamhaFrom:Chemistry - A European Journal (Vol. 26, Issue 41) Peer-Reviewed

  July 22, 202032 words Report, Brief articl...

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• Select The interactions of amphiphilic antisense oligonucleotides with serum proteins and their effects on in vitro silencing activity

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  The interactions of amphiphilic antisense oligonucleotides with serum proteins and their effects on in vitro silencing activity

  Authors:Arnaud E. Felber, NuRia Bayo-Puxan, Glen F. Deleavey, Bastien Castagner, Masad J. Damha, and Jean-Christophe LerouxFrom:Biomaterials (Vol. 33, Issue 25) Peer-Reviewed

  Sept. 2012 Report

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• Select 2'F-arabinonucleic acids (2'F-ANA)--history, properties, and new frontiers

  6

  2'F-arabinonucleic acids (2'F-ANA)--history, properties, and new frontiers

  Authors:Jonathan K. Watts and Masad J. DamhaFrom:Canadian Journal of Chemistry (Vol. 86, Issue 7) Peer-Reviewed

  July 200811,814 words Report 1470LAbstract: The development of arabinonucleosides and oligoarabinonucleotides is described, focusing especially on 2'-deoxy-2'-fluoroarabinonucleosides (araF-N) and -oligonucleotides (2T-ANA). In addition to their...
• Select Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.

  7

  Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.

  Authors:Yazan M. Abbas, Beatrice Theres Laudenbach, Saul Martfnez-Montero, Regina Cencic, Matthias Habjan, Andreas Pichlmair, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 114, Issue 11) Peer-Reviewed

  Mar. 14, 201710,862 words Report 1490L

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• Select Click conjugated polymeric immuno-nanoparticles for targeted siRNA and antisense oligonucleotide delivery

  8

  Click conjugated polymeric immuno-nanoparticles for targeted siRNA and antisense oligonucleotide delivery

  Authors:Dianna P.Y. Chan, Glen F. Deleavey, Shawn C. Owen, Masad J. Damha, and Molly S. ShoichetFrom:Biomaterials (Vol. 34, Issue 33) Peer-Reviewed

  Nov. 2013262 words Article

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• Select Tricyclic "oxadiazaphosphorine oxide" guanosines A new strategy to functionalize guanosine at the exocyclic amino group

  9

  Tricyclic "oxadiazaphosphorine oxide" guanosines A new strategy to functionalize guanosine at the exocyclic amino group

  Authors:SeBastien Robidoux, Yunkui Guo, and Masad J. DamhaFrom:Tetrahedron Letters (Vol. 36, Issue 37) Peer-Reviewed

  Sept. 11, 199586 words Article

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• Select Probing DNA polymerase activity with stereoisomeric 2-fluoro-[beta]-D-arabinose (2'F-araNTPs) and 2'-fluoro-[beta]-D-ribose (2'F-rNTPs) nucleoside 5'-triphosphates

  10

  Probing DNA polymerase activity with stereoisomeric 2-fluoro-[beta]-D-arabinose (2'F-araNTPs) and 2'-fluoro-[beta]-D-ribose (2'F-rNTPs) nucleoside 5'-triphosphates

  Authors:Chang G. Peng and Masad J. DamhaFrom:Canadian Journal of Chemistry (Vol. 86, Issue 9) Peer-Reviewed

  Sept. 20086,162 words Article 1480L2'-Deoxy-2'-fluoro-[beta]-D-ribonucleosides (2'F-rN) and 2'-deoxy-2'-fluoro-[beta]-D-arabinonucleosides (2'F-araN) differ solely in the stereochemistry at the 2'-carbon of the furanose sugar ring. 2'F-rN...
• Select Design, synthesis, and properties of phosphoramidate 2?,5?-linked branched RNA: toward the rational design of inhibitors of the RNA lariat debranching enzyme

  11

  Design, synthesis, and properties of phosphoramidate 2?,5?-linked branched RNA: toward the rational design of inhibitors of the RNA lariat debranching enzyme

  Authors:Nobuhiro Tago, Adam Katolik, Nathaniel E. Clark, Eric J. Montemayor, Kohji Seio, Mitsuo Sekine, et al.From:Journal of Organic Chemistry (Vol. 80, Issue 20) Peer-Reviewed

  Oct. 16, 201573 words Report

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• Select Dramatic effect of furanose C2' substitution on structure and stability: directing the folding of the human telomeric quadruplex with a single fluorine atom

  12

  Dramatic effect of furanose C2' substitution on structure and stability: directing the folding of the human telomeric quadruplex with a single fluorine atom

  Authors:Nerea Martin-Pintado, Glen F. Deleavey, Modesto Orozco, Masad J. Damha, Carlos Gonzalez, Maryam Yahyaee-Anzahaee, et al.From:Journal of the American Chemical Society (Vol. 135, Issue 14) Peer-Reviewed

  Apr. 10, 201335 words Report

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• Select New light labile linker for solid phase synthesis of 2'-O-acetalester oligonucleotides and applications to siRNA prodrug development

  13

  New light labile linker for solid phase synthesis of 2'-O-acetalester oligonucleotides and applications to siRNA prodrug development

  Authors:Richard Johnsson, Jeremy G. Lackey, Jovanka J. Bogojeski, and Masad J. DamhaFrom:Bioorganic & Medicinal Chemistry Letters (Vol. 21, Issue 12) Peer-Reviewed

  June 15, 201169 words Article

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• Select Synthesis and biophysical properties of arabinonucleic acids (ANA): circular dichroic spectra, melting temperatures, and ribonuclease H susceptibility of ANA . RNA hybrid duplexes

  14

  Synthesis and biophysical properties of arabinonucleic acids (ANA): circular dichroic spectra, melting temperatures, and ribonuclease H susceptibility of ANA . RNA hybrid duplexes

  Authors:Anne M. Noronha, Christopher J. Wilds, Chun-Nam Lok, Katya Viazovkina, Dominique Arion, Michael A. Parniak, et al.From:Biochemistry (Vol. 39, Issue 24) Peer-Reviewed

  June 20, 200027 words Article

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• Select Remarkable stability of hairpins containing 2',5'-linked RNA loops

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  Remarkable stability of hairpins containing 2',5'-linked RNA loops

  Authors:Rami N. Hannoush and Masad J. DamhaFrom:Journal of the American Chemical Society (Vol. 123, Issue 49) Peer-Reviewed

  Dec. 12, 200139 words Article

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• Select Fiber-optic DNA sensor for fluorometric nucleic acid determination

  16

  Fiber-optic DNA sensor for fluorometric nucleic acid determination

  Authors:Paul A.E. Piunno, Ulrich J. Krull, Robert H.E. Hudson, Masad J. Damha, and Huguette CohenFrom:Analytical Chemistry (Vol. 67, Issue 15) Peer-Reviewed

  Aug. 1, 1995188 words Article

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• Select Exploring Atypical Fluorine-Hydrogen Bonds and Their Effects on Nucleoside Conformations

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  Exploring Atypical Fluorine-Hydrogen Bonds and Their Effects on Nucleoside Conformations

  Authors:Daniel O'Reilly, Robin S. Stein, Mihai Burai Patrascu, Sunit Kumar Jana, Jerry Kurian, Nicolas Moitessier, et al.From:Chemistry - A European Journal (Vol. 24, Issue 61) Peer-Reviewed

  Nov. 2, 2018244 words Report

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• Select Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion

  18

  Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion

  Authors:Xiulong Shen, Audrius Kilikevicius, Daniel O'Reilly, Thazha P. Prakash, Masad J. Damha, Frank Rigo, et al.From:Bioorganic & Medicinal Chemistry Letters (Vol. 28, Issue 17) Peer-Reviewed

  Sept. 15, 2018285 words Report

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• Select Oxepane nucleic acids: Synthesis, characterization, and properties of oligonucleotides bearing a seven-membered carbohydrate ring

  19

  Oxepane nucleic acids: Synthesis, characterization, and properties of oligonucleotides bearing a seven-membered carbohydrate ring

  Authors:David Sabatino and Masad J. DamhaFrom:Journal of the American Chemical Society (Vol. 129, Issue 26) Peer-Reviewed

  July 4, 200752 words Report

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• Select siRNA nanocarriers based on methacrylic acid copolymers

  20

  siRNA nanocarriers based on methacrylic acid copolymers

  Authors:Arnaud E. Felber, Bastien Castagner, Mahmoud Elsabahy, Glen F. Deleavey, Masad J. Damha, and Jean-Christophe LerouxFrom:Journal of Controlled Release (Vol. 152, Issue 1) Peer-Reviewed

  May 30, 2011 Article

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