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    Academic Journals

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• Platelets accumulate in lung lesions of tuberculosis patients and inhibit T-cell responses and Mycobacterium tuberculosis replication in macrophages.

  Authors:Marco P. La Manna, Valentina Orlando, Giusto D. Badami, Bartolo Tamburini, Mojtaba Shekarkar Azgomi, Elena Lo Presti, et al.From:European Journal of Immunology (Vol. 52, Issue 5) Peer-Reviewed

  May 2022259 words Report, Brief articl...

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• Buffy coat-derived platelets cryopreserved using a new method: Results from a pivotal clinical trial on thrombocytopenic patients with acute leukaemia.

  Authors:Mariasanta Napolitano, Salvatrice Mancuso, Simona Raso, Lucio LoCoco, Piera Stefania Arfò, Giovanni De Francisci, et al.From:Transfusion and Apheresis Science (Vol. 58, Issue 6) Peer-Reviewed

  Dec. 2019315 words Report, Brief articl...

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• Quantitative and qualitative profiles of circulating monocytes may help identifying tuberculosis infection and disease stages

  Authors:Marco Pio La Manna, Valentina Orlando, Francesco Dieli, Paola Di Carlo, Antonio Cascio, Gilda Cuzzi, et al.From:PLoS ONE (Vol. 12, Issue 2) Peer-Reviewed

  Feb. 16, 20175,197 words Report 1530LTuberculosis (TB) is one of the most important cause of morbidity and death among infectious diseases, and continuous efforts are needed to improve diagnostic tools and therapy. Previous published studies showed that...

• Role of hematopoietic cells in Mycobacterium tuberculosis infection.

  Authors:Bartolo Tamburini, Giusto Davide Badami, Mojtaba Shekarkar Azgomi, Francesco Dieli, Marco Pio La Manna, and Nadia CaccamoFrom:Tuberculosis (Vol. 130) Peer-Reviewed

  Sept. 2021318 words Report, Brief articl...

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• Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines

  Authors:Nadia Caccamo, Gabriella Pietra, Lucy C. Sullivan, Andrew G. Brooks, Teresa Prezzemolo, Marco P. Manna, et al.From:European Journal of Immunology (Vol. 45, Issue 4) Peer-Reviewed

  Apr. 2015458 words Report

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• Chemotherapy accelerates immune-senescence and functional impairments of V[delta]2pos T cells in elderly patients affected by liver metastatic colorectal cancer.

  Authors:Elena Bruni, Valentina Cazzetta, Matteo Donadon, Matteo Cimino, Guido Torzilli, Gianmarco Spata, et al.From:Journal for ImmunoTherapy of Cancer (Vol. 7, Issue 1) Peer-Reviewed

  Dec. 11, 20194,731 words Article 1660LHuman (gamma delta) [gamma][delta] T cells are unconventional innate-like lymphocytes displaying a broad array of anti-tumor activities with promising perspectives in cancer immunotherapy. In this context,...

• Identification of epitopes of Mycobacterium tuberculosis 16-kDa protein recognized by human leukocyte antigen-A *0201 CD8+ T lymphocytes

  Authors:Nadia Caccamo, Salvatore Milano, Caterina Di Sano, Diego Cigna, Juraj Ivanyi, Alan M. Krensky, et al.From:Journal of Infectious Diseases (Vol. 186, Issue 7) Peer-Reviewed

  Oct. 1, 2002 Article

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• Guidelines for the use of flow cytometry and cell sorting in immunological studies

  Authors:Andrea Cossarizza, Hyun-Dong Chang, Andreas Radbruch, Immanuel Andra, Francesco Annunziato, Petra Bacher, et al.From:European Journal of Immunology (Vol. 47, Issue 10) Peer-Reviewed

  Oct. 2017615 words Report

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• Downregulation of miRNA17-92 cluster marks V[gamma]9V[delta]2 T cells from patients with rheumatoid arthritis

  Authors:Giuliana Guggino, Valentina Orlando, Laura Saieva, Piero Ruscitti, Paola Cipriani, Marco Pio La Manna, et al.From:Arthritis Research & Therapy (Vol. 20, Issue 1) Peer-Reviewed

  Oct. 22, 20185,179 words Report 1650LBackground We aimed to evaluate the phenotype, function, and microRNA (miRNA)17-92 cluster expression in V[gamma]9V[delta]2 T-cell subsets and the correlation with immune response in rheumatoid arthritis (RA)...

• WHOLE BODY IRRADIATION INDUCES IFN-[gamma] PRODUCTION IN BALB/c MICE BY PREVENTING THE APPEARANCE OF A V[alpha]14.sup.+NK T DOWNREGULATORY POPULATION

  Authors:Francesco Dieli, Masaru Taniguchi, Geoffrey L. Asherson, Guido Sireci, Caterina Di Sano, Diego Cigna, et al.From:Cytokine (Vol. 12, Issue 9) Peer-Reviewed

  Sept. 2000128 words Article

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• Analysis of Mycobacterium tuberculosis-Specific CD8 T-Cells in Patients with Active Tuberculosis and in Individuals with Latent Infection

  Authors:Nadia Caccamo, Giuliana Guggino, Serena Meraviglia, Giuseppe Gelsomino, Paola Di Carlo, Lucina Titone, et al.From:PLoS ONE (Vol. 4, Issue 5) Peer-Reviewed

  May 13, 20096,932 words Article 1630LCD8 T-cells contribute to control of Mycobacterium tuberculosis infection, but little is known about the quality of the CD8 T-cell response in subjects with latent infection and in patients with active tuberculosis...

• Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRV[delta]1 and TCRV[delta]2 [gamma][delta] T lymphocytes.

  Authors:Gabriele Pizzolato, Hannah Kaminski, Marie Tosolini, Franchini Don-Marc, Frederic Pont, Frederic Martins, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 116, Issue 24) Peer-Reviewed

  June 11, 20199,096 words Article 1650L

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• Three Cell Subsets Are Required for the Transfer of Delayed-Type Hypersensitivity Reaction by Antigen-Specific T Cell Lines

  Authors:Alfredo Salerno, Francesco Dieli, Guido Sireci, Angelo Bellavia, Vittorio Colizzi, Wlodzmierz Ptak, et al.From:Cellular Immunology (Vol. 175, Issue 2) Peer-Reviewed

  Feb. 1, 1997217 words Article

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• Skewed Differentiation of Circulating V[gamma]9V[delta]2 T Lymphocytes in Melanoma and Impact on Clinical Outcome

  Authors:Francesca Toia, Simona Buccheri, Ampelio Anfosso, Francesco Moschella, Francesco Dieli, Serena Meraviglia, et al.From:PLoS ONE (Vol. 11, Issue 2) Peer-Reviewed

  Feb. 25, 20165,906 words Report 1650LObjective The aim of this study was to evaluate over time circulating [gamma][delta] T lymphocytes in melanoma patients in terms of frequency, effector functions, and relationship with clinical stage and evolution,...

• Combined platelet-rich plasma and lipofilling treatment provides great improvement in facial skin-induced lesion regeneration for scleroderma patients

  Authors:Frances VirzAaAaAeAa[logical not], Paola Bianca, Alessandro Giammona, Tiziana Apuzzo, Simone Di Franco, Laura Rosa Mangiapane, et al.From:Stem Cell Research & Therapy (Vol. 8, Issue 1) Peer-Reviewed

  Oct. 23, 20175,582 words Report 1490LBackground The use of stem cells, including mesenchymal stem cells (MSCs), for regenerative medicine is gaining interest for the clinical benefits so far obtained in patients. This study investigates the use of...

• Efficacy and Safety of the Oral Multikinase Regorafenib in Metastatic Colorectal Cancer

  Authors:Giuseppe Cicero, Rossella De Luca, and Francesco DieliFrom:Oncology (Vol. 93, Issue 6) Peer-Reviewed

  Dec. 1, 20173,448 words Report 1490LBackground/Aim: A clinical trial demonstrated that treatment with oral multikinase regorafenib improved overall survival (OS), progression-free survival (PFS), and disease control [García-Alfonso et al.: J Clin...

• [gamma]δ T cells as a potential tool in colon cancer immunotherapy

  Authors:Thiranut Ramutton, Simona Buccheri, Francesco Dieli, Matilde Todaro, Giorgio Stassi, and Serena MeravigliaFrom:Immunotherapy (Vol. 6, Issue 9) Peer-Reviewed

  Sept. 20149,195 words Report 1930LAuthor(s): Thiranut Ramutton aff1 , Simona Buccheri aff1 aff2 , Francesco Dieli [*] aff1 aff2 , Matilde Todaro aff2 aff3 , Giorgio Stassi aff3 , Serena Meraviglia aff1 Keywords: colon cancer; HDAC inhibitor;...

• Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines

  Authors:Steven G. Smith, Kaatje Smits, Simone A. Joosten, Krista E. van Meijgaarden, Iman Satti, Helen A. Fletcher, et al.From:PLoS ONE (Vol. 10, Issue 9) Peer-Reviewed

  Sept. 14, 20158,297 words Article 1620LIntracellular cytokine staining combined with flow cytometry is one of a number of assays designed to assess T-cell immune responses. It has the specific advantage of enabling the simultaneous assessment of multiple...

• CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA

  Authors:Alice Conigliaro, Viviana Costa, Alessia Lo Dico, Laura Saieva, Simona Buccheri, Francesco Dieli, et al.From:Molecular Cancer (Vol. 14, Issue 1) Peer-Reviewed

  Aug. 14, 20156,104 words Article 1510LBackground CD90+ liver cancer cells have been described as cancer stem-cell-like (CSC), displaying aggressive and metastatic phenotype. Using two different in vitro models, already described as CD90+ liver cancer...

• IL-18/IL-37/IP-10 signalling complex as a potential biomarker for discriminating active and latent TB.

  Authors:Sebastian Wawrocki, Michal Seweryn, Grzegorz Kielnierowski, Wieslawa Rudnicka, Marcin Wlodarczyk, Magdalena Druszczynska, et al.From:PLoS ONE (Vol. 14, Issue 12) Peer-Reviewed

  Dec. 10, 20196,853 words Article 1510LBackground Currently, there are serious limitations in the direct diagnosis of active tuberculosis (ATB). We evaluated the levels of the IL-18/IL-37/IP-10 signalling complex proteins in Mycobacterium tuberculosis...