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From:PLoS ONE (Vol. 14, Issue 12) Peer-ReviewedBackground Validation of previously identified candidate biomarkers and identification of additional candidate gene expression profiles to facilitate diagnosis of tuberculosis (TB) disease and monitoring treatment...
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From:PLoS Neglected Tropical Diseases (Vol. 10, Issue 5) Peer-ReviewedEpidemiological differences exist between Mycobacterium africanum (Maf)- and Mycobacterium tuberculosis (Mtb)-infected patients, but to date, contributing host factors have not been characterised. We analysed clinical...
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From:PLoS ONE (Vol. 10, Issue 5) Peer-ReviewedBackground Sterile protection in >90% of volunteers against homologous Plasmodium falciparum infection has been achieved only using the controlled human malaria infection (CHMI) model. This efficient model involves...
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From:PLoS ONE (Vol. 6, Issue 9) Peer-ReviewedDetermining what constitutes protective immunity to TB is critical for the development of improved diagnostics and vaccines. The comparison of the immune system between contacts of TB patients, who later develop TB...
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From:PLoS Pathogens (Vol. 11, Issue 3) Peer-ReviewedMycobacterial antigens are not exclusively presented to T-cells by classical HLA-class Ia and HLA-class II molecules, but also through alternative antigen presentation molecules such as CD1a/b/c, MR1 and HLA-E. We...
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From:Physiological Reports (Vol. 3, Issue 7) Peer-ReviewedAbstract: Low environmental temperatures have a profound effect on biological processes in the body, including the immune system. Cold exposure coincides with hormonal changes, which may directly or indirectly alter...
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From:Tuberculosis (Vol. 100) Peer-Reviewed
Discriminative expression of whole blood genes in HIV patients with latent and active TB in Ethiopia
Abstract Only