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    Academic Journals

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• Platelets accumulate in lung lesions of tuberculosis patients and inhibit T-cell responses and Mycobacterium tuberculosis replication in macrophages.

  Authors:Marco P. La Manna, Valentina Orlando, Giusto D. Badami, Bartolo Tamburini, Mojtaba Shekarkar Azgomi, Elena Lo Presti, et al.From:European Journal of Immunology (Vol. 52, Issue 5) Peer-Reviewed

  May 2022259 words Report, Brief articl...

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• Impact of antiretroviral and tuberculosis therapies on CD4.sup.+ and CD8.sup.+ HIV/M. tuberculosis-specific T-cell in co-infected subjects

  Authors:Teresa Chiacchio, Elisa Petruccioli, Valentina Vanini, Gilda Cuzzi, Marco Pio La Manna, Valentina Orlando, et al.From:Immunology Letters (Vol. 198) Peer-Reviewed

  June 2018635 words Report

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• Buffy coat-derived platelets cryopreserved using a new method: Results from a pivotal clinical trial on thrombocytopenic patients with acute leukaemia.

  Authors:Mariasanta Napolitano, Salvatrice Mancuso, Simona Raso, Lucio LoCoco, Piera Stefania Arfò, Giovanni De Francisci, et al.From:Transfusion and Apheresis Science (Vol. 58, Issue 6) Peer-Reviewed

  Dec. 2019315 words Report, Brief articl...

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• Quantitative and qualitative profiles of circulating monocytes may help identifying tuberculosis infection and disease stages

  Authors:Marco Pio La Manna, Valentina Orlando, Francesco Dieli, Paola Di Carlo, Antonio Cascio, Gilda Cuzzi, et al.From:PLoS ONE (Vol. 12, Issue 2) Peer-Reviewed

  Feb. 16, 20175,197 words Report 1530LTuberculosis (TB) is one of the most important cause of morbidity and death among infectious diseases, and continuous efforts are needed to improve diagnostic tools and therapy. Previous published studies showed that...

• Role of hematopoietic cells in Mycobacterium tuberculosis infection.

  Authors:Bartolo Tamburini, Giusto Davide Badami, Mojtaba Shekarkar Azgomi, Francesco Dieli, Marco Pio La Manna, and Nadia CaccamoFrom:Tuberculosis (Vol. 130) Peer-Reviewed

  Sept. 2021318 words Report, Brief articl...

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• Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines

  Authors:Nadia Caccamo, Gabriella Pietra, Lucy C. Sullivan, Andrew G. Brooks, Teresa Prezzemolo, Marco P. Manna, et al.From:European Journal of Immunology (Vol. 45, Issue 4) Peer-Reviewed

  Apr. 2015458 words Report

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• Identification of epitopes of Mycobacterium tuberculosis 16-kDa protein recognized by human leukocyte antigen-A *0201 CD8+ T lymphocytes

  Authors:Nadia Caccamo, Salvatore Milano, Caterina Di Sano, Diego Cigna, Juraj Ivanyi, Alan M. Krensky, et al.From:Journal of Infectious Diseases (Vol. 186, Issue 7) Peer-Reviewed

  Oct. 1, 2002 Article

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• Downregulation of miRNA17-92 cluster marks V[gamma]9V[delta]2 T cells from patients with rheumatoid arthritis

  Authors:Giuliana Guggino, Valentina Orlando, Laura Saieva, Piero Ruscitti, Paola Cipriani, Marco Pio La Manna, et al.From:Arthritis Research & Therapy (Vol. 20, Issue 1) Peer-Reviewed

  Oct. 22, 20185,179 words Report 1650LBackground We aimed to evaluate the phenotype, function, and microRNA (miRNA)17-92 cluster expression in V[gamma]9V[delta]2 T-cell subsets and the correlation with immune response in rheumatoid arthritis (RA)...

• Analysis of Mycobacterium tuberculosis-Specific CD8 T-Cells in Patients with Active Tuberculosis and in Individuals with Latent Infection

  Authors:Nadia Caccamo, Giuliana Guggino, Serena Meraviglia, Giuseppe Gelsomino, Paola Di Carlo, Lucina Titone, et al.From:PLoS ONE (Vol. 4, Issue 5) Peer-Reviewed

  May 13, 20096,932 words Article 1630LCD8 T-cells contribute to control of Mycobacterium tuberculosis infection, but little is known about the quality of the CD8 T-cell response in subjects with latent infection and in patients with active tuberculosis...

• Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines

  Authors:Steven G. Smith, Kaatje Smits, Simone A. Joosten, Krista E. van Meijgaarden, Iman Satti, Helen A. Fletcher, et al.From:PLoS ONE (Vol. 10, Issue 9) Peer-Reviewed

  Sept. 14, 20158,297 words Article 1620LIntracellular cytokine staining combined with flow cytometry is one of a number of assays designed to assess T-cell immune responses. It has the specific advantage of enabling the simultaneous assessment of multiple...

• Identification of plasma biomarkers for discrimination between tuberculosis infection/disease and pulmonary non tuberculosis disease

  Authors:Marco Pio La Manna, Valentina Orlando, Paolo Li Donni, Guido Sireci, Paola Di Carlo, Antonio Cascio, et al.From:PLoS ONE (Vol. 13, Issue 3) Peer-Reviewed

  Mar. 15, 20185,449 words Report 1710LAuthor(s): Marco Pio La Manna 1, Valentina Orlando 1, Paolo Li Donni 2, Guido Sireci 1,3, Paola Di Carlo 4, Antonio Cascio 4, Francesco Dieli 1,3, Nadia Caccamo 1,3,* Introduction Tuberculosis (TB) continues to be...

• Lymphocyte apoptosis in children with central nervous system tuberculosis: a case control study

  Authors:Paola Di Carlo, Alessandra Casuccio, Amelia Romano, Daria Spicola, Lucina Titone, Nadia Caccamo, et al.From:BMC Pediatrics (Vol. 11) Peer-Reviewed

  Nov. 23, 20114,429 words Report 1480LBackground Studies of the apoptosis mechanisms involved in the pathogenesis of tuberculosis have suggested that Mycobacterium tuberculosis can actively interfere with the apoptosis of infected cells. In vivo studies...

• Immunomodulatory role of statins in autoimmune disease: is there a role for human [gamma][delta]T cells?

  Authors:Francesco Dieli and Nadia CaccamoFrom:Nature Reviews Immunology (Vol. 6, Issue 7) Peer-Reviewed

  July 2006966 words Article Author(s): Francesco Dieli [1]; Nadia Caccamo [2] It is noteworthy that statins have immunosuppressive and anti-inflammatory properties that seem to be mediated through nonsterol mevalonate products [1]. Statins also...

• Inflammation and the coagulation system in tuberculosis: Tissue Factor leads the dance

  Authors:Nadia Caccamo and Francesco DieliFrom:European Journal of Immunology (Vol. 46, Issue 2) Peer-Reviewed

  Feb. 2016218 words Report

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• Buffy coat-derived platelets cryopreserved using a new method: Results from in vitro studies

  Authors:Mariasanta Napolitano, Salvatrice Mancuso, Lucio Lo Coco, Piera Stefania Arfo, Simona Raso, Giovanni De Francisci, et al.From:Transfusion and Apheresis Science (Vol. 57, Issue 4) Peer-Reviewed

  Aug. 2018380 words Clinical report

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• Human [CD8.sup.+] T-cells recognizing peptides from mycobacterium tuberculosis (Mtb) presented by HLA-E have an Unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset

  Authors:Krista E. van Meijgaarden, Marielle C. Haks, Nadia Caccamo, Francesco Dieli, Tom H.M. Ottenhoff, and Simone A. JoostenFrom:PLoS Pathogens (Vol. 11, Issue 3) Peer-Reviewed

  Mar. 201510,789 words Report 1590LMycobacterial antigens are not exclusively presented to T-cells by classical HLA-class Ia and HLA-class II molecules, but also through alternative antigen presentation molecules such as CD1a/b/c, MR1 and HLA-E. We...

• Th0 to Th1 switch of CD4 T cell clones specific from the 16-kDa antigen of Mycobacterium tuberculosis after successful therapy: lack of involvement of epitope repertoire and HLA-DR

  Authors:Nadia Caccamo, Serena Meraviglia, Francesco Dieli, Amelia Romano, Lucina Titone, and Alfredo SalernoFrom:Immunology Letters (Vol. 98, Issue 2) Peer-Reviewed

  May 15, 2005207 words Report

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• LIODetect[R]TB-ST: Evaluation of novel blood test for a rapid diagnosis of active pulmonary and extra-pulmonary tuberculosis in IGRA confirmed patients.

  Authors:Marco Pio La Manna, Bartolo Tamburini, Valentina Orlando, Giusto Davide Badami, Paola Di Carlo, Antonio Cascio, et al.From:Tuberculosis (Vol. 130) Peer-Reviewed

  Sept. 2021279 words Report, Brief articl...

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• Granulysin-dependent killing of intracellular and extracellular Mycobacterium tuberculosis by V[gamma]9/V[delta]2 T lymphocytes

  Authors:Francesco Dieli, Marita Troye-Blomberg, Juraj Ivanyi, Jean Jacques Fournie, Alan M. Krensky, Marc Bonneville, et al.From:Journal of Infectious Diseases (Vol. 184, Issue 8) Peer-Reviewed

  Oct. 15, 2001 Article

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• Harnessing HLA-E-restricted CD8 T lymphocytes for adoptive cell therapy of patients with severe COVID-19.

  Authors:Nadia Caccamo, Lucy C. Sullivan, Andrew G. Brooks, and Francesco DieliFrom:British Journal of Haematology (Vol. 190, Issue 4) Peer-Reviewed

  Aug. 202029 words Report, Brief articl...

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