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From:BMC Microbiology (Vol. 8) Peer-ReviewedBackground The histone-like Hlp protein is emerging as a key component in mycobacterial pathogenesis, being involved in the initial events of host colonization by interacting with laminin and glycosaminoglycans...
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From:BMC Medical Genetics (Vol. 13) Peer-ReviewedBackground There is reason to expect strong genetic influences on the risk of developing active pulmonary tuberculosis (TB) among latently infected individuals. Many of the genome wide linkage and association studies...
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From:BMC Infectious Diseases (Vol. 14, Issue 1) Peer-ReviewedAuthor(s): Adane Mihret1,2 , Andre G Loxton3 , Yonas Bekele1 , Stefan HE Kaufmann4 , Martin Kidd5 , Mariëlle C Haks6 , Tom HM Ottenhoff6 , Abraham Aseffa1 , Rawleigh Howe1 and Gerhard Walzl3 Background An...
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From:Journal of Immunology Research (Vol. 2017) Peer-ReviewedLatent tuberculosis infection (LTBI) is evidence of immunological control of tuberculosis. Dormancy survival regulator (DosR) regulon-encoded proteins may have a role in the maintenance of LTBI. T cell responses to...