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    Academic Journals

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• Select Tumor necrosis factor-alpha promoter variants and iron phenotypes in 785 Hemochromatosis and Iron Overload Screening (HEIRS) Study participants

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  Tumor necrosis factor-alpha promoter variants and iron phenotypes in 785 Hemochromatosis and Iron Overload Screening (HEIRS) Study participants

  Authors:Ronald T. Acton, James C. Barton, Catherine Leiendecker-Foster, Christopher Zaun, Christine E. McLaren, and John H. EckfeldtFrom:Blood Cells, Molecules and Diseases (Vol. 44, Issue 4) Peer-Reviewed

  Apr. 15, 2010373 words Report

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• Select HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women

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  HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women

  Authors:Charles D Warne, Sophie G Zaloumis, Nadine A Bertalli, Martin B Delatycki, Amanda J Nicoll, Christine E McLaren, et al.From:Journal of Gastroenterology and Hepatology (Vol. 32, Issue 4) Peer-Reviewed

  Apr. 2017450 words Report

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• Select Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels.

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  Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels.

  Authors:Eriza S. Secondes, Daniel F. Wallace, Gautam Rishi, Gordon D. McLaren, Christine E. McLaren, Wen-Pin Chen, et al.From:Blood Cells, Molecules and Diseases (Vol. 85) Peer-Reviewed

  Nov. 2020434 words Report

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• Select Angiogenesis in the progression of breast ductal proliferations

  4

  Angiogenesis in the progression of breast ductal proliferations

  Authors:Philip M. Carpenter, Wen-Pin Chen, Aaron Mendez, Christine E. McLaren, and Min-Ying SuFrom:International Journal of Surgical Pathology (Vol. 19, Issue 3) Peer-Reviewed

  June 2011 Report

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• Select Effects of Difluoromethylornithine Chemoprevention on Audiometry Thresholds and Otoacoustic Emissions

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  Effects of Difluoromethylornithine Chemoprevention on Audiometry Thresholds and Otoacoustic Emissions

  Authors:Karen J. Doyle, Christine E. McLaren, Janet E. Shanks, Cheryl M. Galus, and Frank L. MeyskensFrom:Archives of Otolaryngology - Head & Neck Surgery (Vol. 127, Issue 5) Peer-Reviewed

  May 2001 Article

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• Select Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major

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  Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major

  Authors:Gary M. Brittenham, Patricia M. Griffith, Arthur W. Nienhuis, Christine E. McLaren, Neal S. Young, Eben E. Tucker, et al.From:The New England Journal of Medicine (Vol. 331, Issue 9) Peer-Reviewed

  Sept. 1, 1994155 words Article

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• Select Impact of factors affecting the residual tumor size diagnosed by MRI following neoadjuvant chemotherapy in comparison to pathology

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  Impact of factors affecting the residual tumor size diagnosed by MRI following neoadjuvant chemotherapy in comparison to pathology

  Authors:Jeon-Hor Chen, Shadfar Bahri, Rita S. Mehta, Philip M. Carpenter, Christine E. McLaren, Wen-Pin Chen, et al.From:Journal of Surgical Oncology (Vol. 109, Issue 2) Peer-Reviewed

  Feb. 2014257 words Article

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• Select Determination of optimal replicate number for validation of imprecision using fluorescence cell-based assays: Proposed practical method

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  Determination of optimal replicate number for validation of imprecision using fluorescence cell-based assays: Proposed practical method

  Authors:Marie C. Bene, Gerald E. Marti, Bruce H. Davis, Christine E. McLaren, Anthony J. Carcio, Linda Wong, et al.From:Cytometry Part B: Clinical Cytometry (Vol. 84, Issue 5) Peer-Reviewed

  September-October 2013338 words Article

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• Select Association Between Celiac Disease and Iron Deficiency in Caucasians, but Not Non-Caucasians.

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  Association Between Celiac Disease and Iron Deficiency in Caucasians, but Not Non-Caucasians.

  Authors:Joseph A. Murray, Stela McLachlan, Paul C. Adams, John H. Eckfeldt, Chad P. Garner, Chris D. Vulpe, et al.From:Clinical Gastroenterology and Hepatology (Vol. 11, Issue 7) Peer-Reviewed

  July 2013830 words Report

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• Select Bivariate mixture models for the joint distribution of repeated serum ferritin and transferrin saturation measured 12 years apart in a cohort of healthy middle-aged Australians.

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  Bivariate mixture models for the joint distribution of repeated serum ferritin and transferrin saturation measured 12 years apart in a cohort of healthy middle-aged Australians.

  Authors:Christine E. McLaren, Wen-Pin Chen, Nadine A. Bertalli, Martin B. Delatycki, Graham G. Giles, Dallas R. English, et al.From:PLoS ONE (Vol. 14, Issue 3) Peer-Reviewed

  Mar. 26, 20192,803 words Report 1530LHomozygosity for the p.C282Y substitution in the HFE protein encoded by the hemochromatosis gene on chromosome 6p (HFE) is a common genetic trait that increases susceptibility to iron overload. McLaren et al. used...
• Select Hemochromatosis and iron-overload screening in a racially diverse population

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  Hemochromatosis and iron-overload screening in a racially diverse population

  Authors:Paul C. Adams, James C. Barton, David M. Reboussin, Christine E. McLaren, Fitzroy W. Dawkins, Gordon D. McLaren, et al.From:The New England Journal of Medicine (Vol. 352, Issue 17) Peer-Reviewed

  Apr. 28, 200551 words Article

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• Select Power calculations for generalized linear models in observational longitudinal studies: A simulation approach in SAS

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  Power calculations for generalized linear models in observational longitudinal studies: A simulation approach in SAS

  Authors:Victor M. GastaA[+ or -]aga, Christine E. McLaren, and Ralph J. DelfinoFrom:Computer Methods and Programs in Biomedicine (Vol. 84, Issue 1) Peer-Reviewed

  Oct. 2006242 words Report

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• Select Genome-Wide Association Study Identifies Genetic Loci Associated with Iron Deficiency

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  Genome-Wide Association Study Identifies Genetic Loci Associated with Iron Deficiency

  Authors:Christine E. McLaren, Chad P. Garner, Clare C. Constantine, Stela McLachlan, Chris D. Vulpe, Beverly M. Snively, et al.From:PLoS ONE (Vol. 6, Issue 3) Peer-Reviewed

  Mar. 31, 20118,127 words Article 1520LThe existence of multiple inherited disorders of iron metabolism in man, rodents and other vertebrates suggests genetic contributions to iron deficiency. To identify new genomic locations associated with iron...
• Select Associations between Single Nucleotide Polymorphisms in Iron-Related Genes and Iron Status in Multiethnic Populations

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  Associations between Single Nucleotide Polymorphisms in Iron-Related Genes and Iron Status in Multiethnic Populations

  Authors:Christine E. McLaren, Stela McLachlan, Chad P. Garner, Chris D. Vulpe, Victor R. Gordeuk, John H. Eckfeldt, et al.From:PLoS ONE (Vol. 7, Issue 6) Peer-Reviewed

  June 22, 20126,488 words Article 1600LThe existence of multiple inherited disorders of iron metabolism suggests genetic contributions to iron deficiency. We previously performed a genome-wide association study of iron-related single nucleotide polymorphisms...
• Select Genetic screening for iron overload: no evidence of discrimination at 1 year: few patients had insurance or employment problems after being screened for hemochromatosis and iron overload

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  Genetic screening for iron overload: no evidence of discrimination at 1 year: few patients had insurance or employment problems after being screened for hemochromatosis and iron overload

  Authors:Mark A. Hall, James C. Barton, Paul C. Adams, Christine E. McLaren, Jacob A. Reiss, Oswaldo Castro, et al.From:Journal of Family Practice (Vol. 56, Issue 10) Peer-Reviewed

  Oct. 20072,625 words Report 1680LAbstract Purpose This study measured the extent of insurance and employment problems associated with population screening for hereditary hemochromatosis and iron overload. Methods 101,168 primary care patients...
• Select Generation of "Virtual" Control Groups for Single Arm Prostate Cancer Adjuvant Trials

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  Generation of "Virtual" Control Groups for Single Arm Prostate Cancer Adjuvant Trials

  Authors:Zhenyu Jia, Michael B. Lilly, James A. Koziol, Xin Chen, Xiao-Qin Xia, Yipeng Wang, et al.From:PLoS ONE (Vol. 9, Issue 1) Peer-Reviewed

  Jan. 21, 20145,978 words Article 1550LAuthor(s): Zhenyu Jia 1,10,17,*, Michael B. Lilly 2, James A. Koziol 3, Xin Chen 4, Xiao-Qin Xia 5, Yipeng Wang 6, Douglas Skarecky 7, Manuel Sutton 4, Anne Sawyers 4, Herbert Ruckle 8, Philip M. Carpenter 4, Jessica...
• Select Combined benefit of prediction and treatment: a criterion for evaluating clinical prediction models

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  Combined benefit of prediction and treatment: a criterion for evaluating clinical prediction models

  Authors:Dean Billheimer, Eugene W. Gerner, Christine E. McLaren, and Bonnie LaFleurFrom:Cancer InformaticsPeer-Reviewed

  Oct. 5, 20146,176 words Article 1260LClinical treatment decisions rely on prognostic evaluation of a patient's future health outcomes. Thus, predictive models under different treatment options are key factors for making good decisions. While many criteria...
• Select Melanoma: is hair the root of the problem?

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  Melanoma: is hair the root of the problem?

  Authors:Angela M. Gomez Garcia, Christine E. McLaren, and Frank L. MeyskensFrom:Pigment Cell & Melanoma Research (Vol. 24, Issue 1) Peer-Reviewed

  Feb. 201166 words Report

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• Select Optical imaging correlates with magnetic resonance imaging breast density and revealscomposition changes during neoadjuvant chemotherapy

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  Optical imaging correlates with magnetic resonance imaging breast density and revealscomposition changes during neoadjuvant chemotherapy

  Authors:Thomas D O'Sullivan, Anais Leproux, Jeon-Hor Chen, Shadfar Bahri, Alex Matlock, Darren Roblyer, et al.From:Breast Cancer Research (Vol. 15, Issue 1) Peer-Reviewed

  Feb. 22, 20138,167 words Report 1420LIntroduction In addition to being a risk factor for breast cancer, breast density has beenhypothesized to be a surrogate biomarker for predicting response toendocrine-based chemotherapies. The purpose of this study...
• Select Natural history of HFE simple heterozygosity for C282Y and H63D: A prospective 12-year study

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  Natural history of HFE simple heterozygosity for C282Y and H63D: A prospective 12-year study

  Authors:Sophie G Zaloumis, Katrina J Allen, Nadine A Bertalli, Lidija Turkovic, Martin B Delatycki, Amanda J Nicoll, et al.From:Journal of Gastroenterology and Hepatology (Vol. 30, Issue 4) Peer-Reviewed

  Apr. 2015431 words Clinical report

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