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    Academic Journals

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• Select Hydroxychloroquine Therapy and Serum Immunoglobulin Levels in Women with IgG Subclass Deficiency and Systemic Lupus Erythematosus, Sjögren Syndrome, and Rheumatoid Arthritis: A Retrospective Study.

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  Hydroxychloroquine Therapy and Serum Immunoglobulin Levels in Women with IgG Subclass Deficiency and Systemic Lupus Erythematosus, Sjögren Syndrome, and Rheumatoid Arthritis: A Retrospective Study.

  Authors:James C. Barton, J. Clayborn Barton, and Luigi F. BertoliFrom:Archivum Immunologiae et Therapiae Experimentalis (Vol. 70, Issue 1) Peer-Reviewed

  Dec. 2022295 words Report, Brief articl...

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• Select Iron overload phenotypes and HFE genotypes in white hemochromatosis and iron overload screening study participants without HFE p.C282Y/p.C282Y.

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  Iron overload phenotypes and HFE genotypes in white hemochromatosis and iron overload screening study participants without HFE p.C282Y/p.C282Y.

  Authors:James C. Barton, J. Clayborn Barton, and Ronald T. ActonFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 27, 20226,465 words Report 1490LBackground Screening program participants with iron overload (IO) phenotypes without HFE p.C282Y/p.C282Y are incompletely characterized. Methods We studied white participants who had IO phenotypes without...
• Select Acute kidney injury manifesting as renal tubular acidosis with proximal and distal renal tubular dysfunction in a dog with acute pancreatitis.

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  Acute kidney injury manifesting as renal tubular acidosis with proximal and distal renal tubular dysfunction in a dog with acute pancreatitis.

  Authors:James C. Barton, Peter-John Mäntylä Noble, and Erin M. O'ConnellFrom:Journal of Veterinary Emergency and Critical Care (Vol. 32, Issue 4) Peer-Reviewed

  July-August 2022209 words Report, Brief articl...

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• Select HLA-A*03, the hemochromatosis ancestral haplotype, and phenotypes of referred hemochromatosis probands with HFE p.C282Y homozygosity.

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  HLA-A*03, the hemochromatosis ancestral haplotype, and phenotypes of referred hemochromatosis probands with HFE p.C282Y homozygosity.

  Authors:James C. Barton, J. Clayborn Barton, and Ronald T. ActonFrom:Hereditas (Vol. 159, Issue 1) Peer-Reviewed

  June 6, 20225,972 words Article 1500LBackground Human leukocyte antigen (HLA)-A*03, hemochromatosis ancestral haplotype marker, was associated with greater iron overload in hemochromatosis cohorts reported before discovery of the HFE gene. We sought to...
• Select Tumor necrosis factor-alpha promoter variants and iron phenotypes in 785 Hemochromatosis and Iron Overload Screening (HEIRS) Study participants

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  Tumor necrosis factor-alpha promoter variants and iron phenotypes in 785 Hemochromatosis and Iron Overload Screening (HEIRS) Study participants

  Authors:Ronald T. Acton, James C. Barton, Catherine Leiendecker-Foster, Christopher Zaun, Christine E. McLaren, and John H. EckfeldtFrom:Blood Cells, Molecules and Diseases (Vol. 44, Issue 4) Peer-Reviewed

  Apr. 15, 2010373 words Report

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• Select A Comparison Between Whites and Blacks With Severe Multi-Organ Iron Overload Identified in 16,152 Autopsies

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  A Comparison Between Whites and Blacks With Severe Multi-Organ Iron Overload Identified in 16,152 Autopsies

  Authors:James C. Barton, Ronald T. Acton, Laura E. Anderson, and C. Bruce AlexanderFrom:Clinical Gastroenterology and Hepatology (Vol. 7, Issue 7) Peer-Reviewed

  July 2009156 words Article

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• Select Pagophagia in men with iron-deficiency anemia

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  Pagophagia in men with iron-deficiency anemia

  Authors:James C. Barton, J. Clayborn Barton, and Luigi F. BertoliFrom:Blood Cells, Molecules and Diseases (Vol. 77) Peer-Reviewed

  July 2019302 words Report

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• Select Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels.

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  Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels.

  Authors:Eriza S. Secondes, Daniel F. Wallace, Gautam Rishi, Gordon D. McLaren, Christine E. McLaren, Wen-Pin Chen, et al.From:Blood Cells, Molecules and Diseases (Vol. 85) Peer-Reviewed

  Nov. 2020434 words Report

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• Select Clinical and laboratory associations of mannose-binding lectin in 219 adults with IgG subclass deficiency

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  Clinical and laboratory associations of mannose-binding lectin in 219 adults with IgG subclass deficiency

  Authors:James C. Barton, Jackson C. Barton, and Luigi F. BertoliFrom:BMC Immunology (Vol. 20, Issue 1) Peer-Reviewed

  May 22, 20194,222 words Report 1410LBackground Mannose-binding lectin (MBL) deficiency may increase risk of respiratory tract infection in adults unselected for IgG or IgG subclass levels. In a retrospective study, we sought to determine associations...
• Select Peripheral blood erythrocyte parameters in hemochromatosis: Evidence for increased erythrocyte hemoglobin content

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  Peripheral blood erythrocyte parameters in hemochromatosis: Evidence for increased erythrocyte hemoglobin content

  Authors:James C. Barton, Luigi F. Bertoli, and Barry E. RothenbergFrom:Journal of Laboratory and Clinical Medicine (Vol. 135, Issue 1) Peer-Reviewed

  Jan. 2000383 words Article

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• Select Pneumococcal vaccination responses in adults with subnormal IgG subclass concentrations

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  Pneumococcal vaccination responses in adults with subnormal IgG subclass concentrations

  Authors:Antony R. Parker, Markus Skold, Stephen Harding, J. Clayborn Barton, Luigi F. Bertoli, and James C. BartonFrom:BMC Immunology (Vol. 20, Issue 1) Peer-Reviewed

  Aug. 20, 20195,273 words Report 1430LBackground We sought to compare Pneumovax[R]23 responses in adults with subnormal IgG subclass concentrations. We studied adults with normal total IgG, frequent/severe respiratory infection, and subnormal IgG1, IgG3,...
• Select Intravenous iron dextran therapy in patients with iron deficiency and normal renal function who failed to respond to or did not tolerate oral iron supplementation

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  Intravenous iron dextran therapy in patients with iron deficiency and normal renal function who failed to respond to or did not tolerate oral iron supplementation

  Authors:James C. Barton, Ellen H. Barton, Luigi F. Bertoli, Charlene H. Gothard, and Jennifer S. SherrerFrom:American Journal of Medicine (Vol. 109, Issue 1) Peer-Reviewed

  July 2000 Article

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• Select Selective Subnormal IgG1 in 54 Adult Index Patients with Frequent or Severe Bacterial Respiratory Tract Infections

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  Selective Subnormal IgG1 in 54 Adult Index Patients with Frequent or Severe Bacterial Respiratory Tract Infections

  Authors:James C. Barton, Luigi F. Bertoli, J. Clayborn Barton, and Ronald T. ActonFrom:Journal of Immunology Research (Vol. 2016) Peer-Reviewed

  Annual 20167,195 words Article 1260LWe characterized 54 adult index patients with reports of frequent or severe bacterial respiratory tract infections at diagnosis of selective subnormal IgG1. Mean age was 50 [+ or -] 13 (SD) y; 87.0% were women....
• Select Do positive hemochromatosis studies make for an ironclad diagnosis?

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  Do positive hemochromatosis studies make for an ironclad diagnosis?

  Author:James C. BartonFrom:Consultant (Vol. 44, Issue 10) Peer-Reviewed

  Sept. 1, 2004458 words Article My patient is a 42-year-old man who complains of fatigue. He says that drinking some kind of "sports drink" makes him feel better. His complete blood cell count is normal. His serum ferritin level is 248 ng/mL and his...
• Select A Survey of 2,851 Patients with Hemochromatosis: Symptoms and Response to Treatment

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  A Survey of 2,851 Patients with Hemochromatosis: Symptoms and Response to Treatment

  Authors:Sharon M. McDonnell, Ben L. Preston, Sandy A. Jewell, James C. Barton, Corwin Q. Edwards, Paul C. Adams, et al.From:American Journal of Medicine (Vol. 106, Issue 6) Peer-Reviewed

  June 1999232 words Article

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• Select A diagnostic approach to hyperferritinemia with a non-elevated transferrin saturation

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  A diagnostic approach to hyperferritinemia with a non-elevated transferrin saturation

  Authors:Paul C. Adams and James C. BartonFrom:Journal of Hepatology (Vol. 55, Issue 2) Peer-Reviewed

  Aug. 2011174 words Report

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• Select Dupuytren's contracture in Alabama HFE hemochromatosis probands

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  Dupuytren's contracture in Alabama HFE hemochromatosis probands

  Authors:James C. Barton and J. Clayborn BartonFrom:Clinical Medicine Insights: Arthritis and Musculoskeletal DisordersPeer-Reviewed

  Aug. 21, 20124,731 words Report 1720LBackground: Dupuytren's contracture (DC) and HFE hemochromatosis occur in some of the same at-risk populations and present with similar comorbid conditions. Methods: We estimated DC prevalence in two cohorts of white...
• Select Pica associated with iron deficiency or depletion: clinical and laboratory correlates in 262 non-pregnant adult outpatients

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  Pica associated with iron deficiency or depletion: clinical and laboratory correlates in 262 non-pregnant adult outpatients

  Authors:James C. Barton, J Clayborn Barton, and Luigi F. BertoliFrom:BMC Blood Disorders (Vol. 10) Peer-Reviewed

  Dec. 22, 20106,280 words Report 1340LBackground There are many descriptions of the association of pica with iron deficiency in adults, but there are few reports in which observations available at diagnosis of iron deficiency were analyzed using...
• Select Hemochromatosis and iron-overload screening in a racially diverse population

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  Hemochromatosis and iron-overload screening in a racially diverse population

  Authors:Paul C. Adams, James C. Barton, David M. Reboussin, Christine E. McLaren, Fitzroy W. Dawkins, Gordon D. McLaren, et al.From:The New England Journal of Medicine (Vol. 352, Issue 17) Peer-Reviewed

  Apr. 28, 200551 words Article

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• Select Genetic screening for iron overload: no evidence of discrimination at 1 year: few patients had insurance or employment problems after being screened for hemochromatosis and iron overload

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  Genetic screening for iron overload: no evidence of discrimination at 1 year: few patients had insurance or employment problems after being screened for hemochromatosis and iron overload

  Authors:Mark A. Hall, James C. Barton, Paul C. Adams, Christine E. McLaren, Jacob A. Reiss, Oswaldo Castro, et al.From:Journal of Family Practice (Vol. 56, Issue 10) Peer-Reviewed

  Oct. 20072,625 words Report 1680LAbstract Purpose This study measured the extent of insurance and employment problems associated with population screening for hereditary hemochromatosis and iron overload. Methods 101,168 primary care patients...