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    Academic Journals

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• Select AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale.

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  AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale.

  Authors:Cynthia H. Y. Fu, Guray Erus, Yong Fan, Mathilde Antoniades, Danilo Arnone, Stephen R. Arnott, et al.From:BMC Psychiatry (Vol. 23, Issue 1) Peer-Reviewed

  Jan. 23, 20239,133 words Report 1590LBackground Efforts to develop neuroimaging-based biomarkers in major depressive disorder (MDD), at the individual level, have been limited to date. As diagnostic criteria are currently symptom-based, MDD is...
• Select Risk and protective factors for new-onset binge eating, low weight, and self-harm symptoms in >35,000 individuals in the UK during the COVID-19 pandemic.

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  Risk and protective factors for new-onset binge eating, low weight, and self-harm symptoms in >35,000 individuals in the UK during the COVID-19 pandemic.

  Authors:Helena L. Davies, Christopher Hübel, Moritz Herle, Saakshi Kakar, Jessica Mundy, Alicia J. Peel, et al.From:The International Journal of Eating Disorders (Vol. 56, Issue 1) Peer-Reviewed

  Jan. 2023425 words Report

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• Select Patient characteristics associated with retrospectively self-reported treatment outcomes following psychological therapy for anxiety or depressive disorders - a cohort of GLAD study participants.

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  Patient characteristics associated with retrospectively self-reported treatment outcomes following psychological therapy for anxiety or depressive disorders - a cohort of GLAD study participants.

  Authors:Christopher Rayner, Jonathan R.I. Coleman, Megan Skelton, Cherie Armour, John Bradley, Joshua E.J. Buckman, et al.From:BMC Psychiatry (Vol. 22, Issue 1) Peer-Reviewed

  Nov. 18, 20224,779 words Report 1440LBackground Progress towards stratified care for anxiety and depression will require the identification of new predictors. We collected data on retrospectively self-reported therapeutic outcomes in adults who received...
• Select A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens.

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  A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens.

  Authors:Anton P. Porsteinsson, Srikant Rangaraju, Tara L. Spires-Jones, Kerry O'Banion, Anna J. Stevenson, Daniel L. McCartney, et al.From:European Journal of Neuroscience (Vol. 56, Issue 9) Peer-Reviewed

  Nov. 2022773 words Report

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• Select Local CpG density affects the trajectory and variance of age-associated DNA methylation changes.

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  Local CpG density affects the trajectory and variance of age-associated DNA methylation changes.

  Authors:Jonathan Higham, Lyndsay Kerr, Qian Zhang, Rosie M. Walker, Sarah E. Harris, David M. Howard, et al.From:Genome Biology (Vol. 23, Issue 1) Peer-Reviewed

  Oct. 17, 202212,293 words Article 1500LBackground DNA methylation is an epigenetic mark associated with the repression of gene promoters. Its pattern in the genome is disrupted with age and these changes can be used to statistically predict age with...
• Select Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression.

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  Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression.

  Authors:Kylie P. Glanville, Jonathan R.I. Coleman, Ken B. Hanscombe, Jack Euesden, Shing Wan Choi, Kirstin L. Purves, et al.From:Biological Psychiatry (Vol. 87, Issue 5) Peer-Reviewed

  Mar. 1, 20204,639 words Report

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• Select Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.

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  Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.

  Authors:Gabriëlla A.M. Blokland, Jakob Grove, Chia-Yen Chen, Chris Cotsapas, Stuart Tobet, Robert Handa, et al.From:Biological Psychiatry (Vol. 91, Issue 1) Peer-Reviewed

  Jan. 1, 20225,651 words Report

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• Select White matter integrity and its association with affective and interpersonal symptoms in borderline personality disorder

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  White matter integrity and its association with affective and interpersonal symptoms in borderline personality disorder

  Authors:Heather C. Whalley, Thomas Nickson, Merrick Pope, Katie Nicol, Liana Romaniuk, Mark E. Bastin, et al.From:NeuroImage: Clinical (Vol. 7) Peer-Reviewed

  Jan. 1, 2015500 words Article

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• Select Aberrant structural covariance networks in youth at high familial risk for mood disorder.

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  Aberrant structural covariance networks in youth at high familial risk for mood disorder.

  Authors:Kareen Heinze, Xueyi Shen, Emma Hawkins, Mathew A. Harris, Laura Nooij, Andrew M. McIntosh, et al.From:Bipolar Disorders (Vol. 22, Issue 2) Peer-Reviewed

  Mar. 2020281 words Report, Brief articl...

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• Select DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936.

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  DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936.

  Authors:Anne Seeboth, Daniel L. McCartney, Yunzhang Wang, Robert F. Hillary, Anna J. Stevenson, Rosie M. Walker, et al.From:Clinical Epigenetics (Vol. 12, Issue 1) Peer-Reviewed

  Mar. 26, 20207,462 words Article 1450LBackground DNA methylation outlier burden has been suggested as a potential marker of biological age. An outlier is typically defined as DNA methylation levels at any one CpG site that are three times beyond the...
• Select Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

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  Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

  Authors:Qian Zhang, Costanza L. Vallerga, Rosie M. Walker, Tian Lin, Anjali K. Henders, Grant W. Montgomery, et al.From:Genome Medicine (Vol. 11, Issue 1) Peer-Reviewed

  Aug. 23, 20195,811 words Report 1410LBackground DNA methylation changes with age. Chronological age predictors built from DNA methylation are termed 'epigenetic clocks'. The deviation of predicted age from the actual age ('age acceleration residual',...
• Select Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease.

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  Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease.

  Authors:Daniel L. Mccartney, Anna J. Stevenson, Rosie M. Walker, Jude Gibson, Stewart W. Morris, Archie Campbell, et al.From:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring (Vol. 10, Issue 1) Peer-Reviewed

  June 20, 20186,691 words Report 1310LAbstract: Introduction: The “epigenetic clock” is a DNA methylation–based estimate of biological age and is correlated with chronological age—the greatest risk factor for Alzheimer's disease (AD). Genetic and...
• Select The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia

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  The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia

  Authors:Orla M. Doyle, Catherine Bois, Pippa Thomson, Liana Romaniuk, Brandon Whitcher, Steven C.R. Williams, et al.From:Journal of Clinical Investigation (Vol. 125, Issue 9) Peer-Reviewed

  Sept. 20156,659 words Report 1330LBACKGROUND. The disrupted in schizophrenia 1 (DISCI) gene locus was originally identified in a Scottish pedigree with a high incidence of psychiatric disorders that is associated with a balanced t(1;11)(q42.1;q14.3)...
• Select Effects of environmental risks and polygenic loading for schizophrenia on cortical thickness

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  Effects of environmental risks and polygenic loading for schizophrenia on cortical thickness

  Authors:Emma Neilson, Catherine Bois, Jude Gibson, Barbara Duff, Andrew Watson, Neil Roberts, et al.From:Schizophrenia Research (Vol. 184) Peer-Reviewed

  June 2017451 words Report

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• Select Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

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  Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

  Authors:Robert A. Power, Katherine E. Tansey, Henriette Normolle Buttenschon, Sarah Cohen-Woods, Tim Bigdeli, Lynsey S. Hall, et al.From:Biological Psychiatry (Vol. 81, Issue 4) Peer-Reviewed

  Feb. 15, 20171,284 words Article

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• Select Chronic multisite pain in major depression and bipolar disorder: cross-sectional study of 149,611 participants in UK Biobank

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  Chronic multisite pain in major depression and bipolar disorder: cross-sectional study of 149,611 participants in UK Biobank

  Authors:Barbara I Nicholl, Daniel Mackay, Breda Cullen, Daniel J Martin, Zia Ul-Haq, Frances S Mair, et al.From:BMC Psychiatry (Vol. 14, Issue 1) Peer-Reviewed

  Dec. 10, 20145,701 words Article 1490LAuthor(s): Barbara I Nicholl1 , Daniel Mackay1 , Breda Cullen1 , Daniel J Martin1 , Zia Ul-Haq1 , Frances S Mair1 , Jonathan Evans1 , Andrew M McIntosh2 , John Gallagher1 , Beverly Roberts3 , Ian J Deary3 , Jill P Pell1...
• Select Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: A pilot project of the ENIGMA--DTI working group

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  Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: A pilot project of the ENIGMA--DTI working group

  Authors:Neda Jahanshad, Peter V. Kochunov, Emma Sprooten, Rene C. Mandl, Thomas E. Nichols, Laura Almasy, et al.From:Neuroimage (Vol. 81) Peer-Reviewed

  Nov. 1, 2013744 words Report

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• Select Indicators of mental disorders in UK Biobank-A comparison of approaches

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  Indicators of mental disorders in UK Biobank-A comparison of approaches

  Authors:Katrina A.S. Davis, Breda Cullen, Mark Adams, Anamaria Brailean, Gerome Breen, Jonathan R.I. Coleman, et al.From:International Journal of Methods in Psychiatric Research (Vol. 28, Issue 3) Peer-Reviewed

  Sept. 2019461 words Report

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• Select Diffusion tensor imaging correlates of early markers of depression in youth at high-familial risk for bipolar disorder

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  Diffusion tensor imaging correlates of early markers of depression in youth at high-familial risk for bipolar disorder

  Authors:Rossana Ganzola, Andrew M. McIntosh, Thomas Nickson, Emma Sprooten, Mark E. Bastin, Stephen Giles, et al.From:Journal of Child Psychology and Psychiatry (Vol. 59, Issue 8) Peer-Reviewed

  Aug. 2018390 words Author abstract, Rep...

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• Select The Genetic Links to Anxiety and Depression (GLAD) Study: Online recruitment into the largest recontactable study of depression and anxiety.

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  The Genetic Links to Anxiety and Depression (GLAD) Study: Online recruitment into the largest recontactable study of depression and anxiety.

  Authors:Molly R. Davies, Gursharan Kalsi, Chérie Armour, Ian R. Jones, Andrew M. McIntosh, Daniel J. Smith, et al.From:Behaviour Research and Therapy (Vol. 123) Peer-Reviewed

  Dec. 2019744 words Article

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