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    Academic Journals

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• Select Alzheimer's disease [beta]-amyloid peptides are released in association with exosomes

  1

  Alzheimer's disease [beta]-amyloid peptides are released in association with exosomes

  Authors:Lawrence Rajendran, Masanori Honsho, Tobias R. Zahn, Patrick Keller, Kathrin D. Geiger, Paul Verkade, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 103, Issue 30) Peer-Reviewed

  July 25, 2006197 words Author abstract 60L

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• Select TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss

  2

  TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss

  Authors:Rosa C. Paolicelli, Ali Jawaid, Christopher M. Henstridge, Andrea Valeri, Mario Merlini, John L. Robinson, et al.From:Neuron (Vol. 95, Issue 2) Peer-Reviewed

  July 19, 2017410 words Report

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• Select The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

  3

  The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

  Authors:Fabia Filipello, Raffaella Morini, Irene Corradini, Valerio Zerbi, Alice Canzi, Bernadeta Michalski, et al.From:Immunity (Vol. 48, Issue 5) Peer-Reviewed

  May 15, 2018436 words Report

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• Select Cell-to-cell Communication by Extracellular Vesicles: Focus on Microglia

  4

  Cell-to-cell Communication by Extracellular Vesicles: Focus on Microglia

  Authors:Rosa C. Paolicelli, Giorgio Bergamini, and Lawrence RajendranFrom:Neuroscience (Vol. 405) Peer-Reviewed

  May 1, 2019366 words Report

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• Select Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

  5

  Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

  Authors:Robert Vassar, Peer-Hendrik Kuhn, Christian Haass, Matthew E. Kennedy, Lawrence Rajendran, Philip C. Wong, et al.From:Journal of Neurochemistry (Vol. 130, Issue 1) Peer-Reviewed

  July 2014252 words Report

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• Select Ceramide triggers budding of exosome vesicles into multivesicular endosomes

  6

  Ceramide triggers budding of exosome vesicles into multivesicular endosomes

  Authors:Katarina Trajkovic, Chieh Hsu, Salvatore Chiantia, Lawrence Rajendran, Dirk Wenzel, Felix Wieland, et al.From:Science (Vol. 319, Issue 5867) Peer-Reviewed

  Feb. 29, 2008116 words Author abstract, Rep...

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• Select Role of genes linked to sporadic Alzheimer's disease risk in the production of [beta]-amyloid peptides.

  7

  Role of genes linked to sporadic Alzheimer's disease risk in the production of [beta]-amyloid peptides.

  Authors:Jitin Bali, Ali Hashemi Gheinani, Sebastian Zurbriggen, and Lawrence RajendranFrom:Proceedings of the National Academy of Sciences of the United States (Vol. 109, Issue 38) Peer-Reviewed

  Sept. 18, 2012158 words Report, Author abstr...

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• Select Concise Review: Modeling Neurodegenerative Diseases with Human Pluripotent Stem Cell-Derived Microglia

  8

  Concise Review: Modeling Neurodegenerative Diseases with Human Pluripotent Stem Cell-Derived Microglia

  Authors:Walther Haenseler and Lawrence RajendranFrom:Stem Cells (Vol. 37, Issue 6) Peer-Reviewed

  June 2019216 words Article

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• Select Lipid-anchored drugs for delivery into subcellular compartments

  9

  Lipid-anchored drugs for delivery into subcellular compartments

  Authors:Lawrence Rajendran, Vinod Udayar, and Zoe V. GoodgerFrom:Trends in Pharmacological Sciences (Vol. 33, Issue 4) Peer-Reviewed

  Apr. 2012 Article

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• Select Asymmetric localization of flotillins/reggies in preassembled platforms confers inherent polarity to hematopoietic cells

  10

  Asymmetric localization of flotillins/reggies in preassembled platforms confers inherent polarity to hematopoietic cells

  Authors:Lawrence Rajendran, Madhan Masilamani, Samuel Solomon, Ritva Tikkanen, Claudia A.O. Stuermer, Helmut Plattner, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 100, Issue 14) Peer-Reviewed

  July 8, 2003221 words Author abstract

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• Select The Wide World of Coacervates: From the Sea to Neurodegeneration

  11

  The Wide World of Coacervates: From the Sea to Neurodegeneration

  Authors:Emanuele Astoricchio, Caterina Alfano, Lawrence Rajendran, Piero Andrea Temussi, and Annalisa PastoreFrom:Trends in Biochemical Sciences (Vol. 45, Issue 8) Peer-Reviewed

  Aug. 2020272 words Report

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• Select miR-186 in Alzheimer's disease: a big hope for a small RNA?

  12

  miR-186 in Alzheimer's disease: a big hope for a small RNA?

  Authors:Saoussen Ben Halima, Gabriele Siegel, and Lawrence RajendranFrom:Journal of Neurochemistry (Vol. 137, Issue 3) Peer-Reviewed

  May 201675 words Report

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• Select BACE1 Inhibition Induces a Specific Cerebrospinal Fluid [beta]-Amyloid Pattern That Identifies Drug Effects in the Central Nervous System

  13

  BACE1 Inhibition Induces a Specific Cerebrospinal Fluid [beta]-Amyloid Pattern That Identifies Drug Effects in the Central Nervous System

  Authors:Niklas Mattsson, Lawrence Rajendran, Henrik Zetterberg, Mikael Gustavsson, Ulf Andreasson, Maria Olsson, et al.From:PLoS ONE (Vol. 7, Issue 2) Peer-Reviewed

  Feb. 6, 20125,921 words Article 1600LAuthor(s): Niklas Mattsson 1 , * , Lawrence Rajendran 2 , Henrik Zetterberg 1 , Mikael Gustavsson 1 , Ulf Andreasson 1 , Maria Olsson 1 , Gunnar Brinkmalm 1 , Johan Lundkvist 3 , Laura H. Jacobson 4 , Ludovic Perrot 4 ,...
• Select Efficient inhibition of the Alzheimer's disease [beta]-secretase by membrane targeting

  14

  Efficient inhibition of the Alzheimer's disease [beta]-secretase by membrane targeting

  Authors:Lawrence Rajendran, Anja Schneider, Georg Schlechtingen, Sebastian Weidlich, Jonas Ries, Tobias Braxmeier, et al.From:Science (Vol. 320, Issue 5875) Peer-Reviewed

  Apr. 25, 2008118 words Author abstract, Rep...

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• Select Flotillins Are Involved in the Polarization of Primitive and Mature Hematopoietic Cells

  15

  Flotillins Are Involved in the Polarization of Primitive and Mature Hematopoietic Cells

  Authors:Lawrence Rajendran, Julia Beckmann, Astrid Magenau, Eva-Maria Boneberg, Katharina Gaus, Antonella Viola, et al.From:PLoS ONE (Vol. 4, Issue 12) Peer-Reviewed

  Dec. 22, 20098,260 words Article 1550LAuthor(s): Lawrence Rajendran 1,2,3,*, Julia Beckmann 4,5, Astrid Magenau 6,7, Eva-Maria Boneberg 8, Katharina Gaus 6,7, Antonella Viola 9, Bernd Giebel 4,5,*, Harald Illges 2,8,10,* Introduction Establishment of...
• Select Cellular basis of Alzheimer's disease

  16

  Cellular basis of Alzheimer's disease

  Authors:Jitin Bali, Saoussen Halima, Boas Felmy, Zoe Goodger, Sebastian Zurbriggen, and Lawrence RajendranFrom:Annals of Indian Academy of Neurology (Vol. 13, Issue 6) Peer-Reviewed

  Dec. 20104,392 words Report 1510LByline: Jitin. Bali, Saoussen. Halima, Boas. Felmy, Zoe. Goodger, Sebastian. Zurbriggen, Lawrence. Rajendran Alzheimer's disease (AD) is the most common form of neurodegenerative disease. A characteristic feature of...
• Select Benefits and Harms of Statins in People with Dementia: A Systematic Review and Meta-Analysis.

  17

  Benefits and Harms of Statins in People with Dementia: A Systematic Review and Meta-Analysis.

  Authors:Katrina A.S. Davis, Delia Bishara, Gayan Perera, Mariam Molokhia, Lawrence Rajendran, and Robert J. StewartFrom:Journal of the American Geriatrics Society (Vol. 68, Issue 3) Peer-Reviewed

  Mar. 2020358 words Report, Brief articl...

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• Select Order of lipid phases in model and plasma membranes

  18

  Order of lipid phases in model and plasma membranes

  Authors:Hermann-Josef Kaiser, Daniel Lingwood, Ilya Levental, Julio L. Sampaio, Lucie Kalvodova, Lawrence Rajendran, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 106, Issue 39) Peer-Reviewed

  Sept. 29, 2009251 words Author abstract, Rep...

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• Select The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids

  19

  The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids

  Authors:Adriano Aguzzi and Lawrence RajendranFrom:Neuron (Vol. 64, Issue 6) Peer-Reviewed

  Dec. 24, 2009150 words Report

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• Select Subcellular targeting strategies for drug design and delivery

  20

  Subcellular targeting strategies for drug design and delivery

  Authors:Lawrence Rajendran, Hans-Joachim Knolkers, and Kai SimonsFrom:Nature Reviews Drug Discovery (Vol. 9, Issue 1) Peer-Reviewed

  Jan. 201010,599 words Report 1340LMany drug targets are localized to particular subcellular compartments, yet current drug design strategies are focused on bioavailability and tissue targeting and rarely address drug delivery to specific intracellular...