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From:Clinical Pharmacokinetics (Vol. 45, Issue 11) Peer-ReviewedThe approach to paediatric drug dosing needs to be based on the physiological characteristics of the child and the pharmacokinetic parameters of the drug. This review summarises the current knowledge on developmental...
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From:Clinical Pharmacokinetics (Vol. 48, Issue 10) Peer-Reviewed
Effect of cytochrome P450 2D6 genotype on maternal paroxetine plasma concentrations during pregnancy
Background and Objective: Increasing numbers of women in childbearing years are treated with antidepressants. Concerns regarding fetal exposure to medication has led to large studies on drug effects on birth outcome and...