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From:PLoS ONE (Vol. 17, Issue 2) Peer-ReviewedThe C29197T mutation is one of 4 point mutations known to cause N-gene target failure (NGTF) in the Xpert Xpress SARS-CoV-2 and Xpert Omni SARS-CoV-2 assays from Cepheid (Sunnyvale, CA). We describe a high local...
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From:Nature Medicine (Vol. 26, Issue 6) Peer-ReviewedIncreasingly, public-health agencies are using pathogen genomic sequence data to support surveillance and epidemiological investigations. As access to whole-genome sequencing has grown, greater amounts of molecular data...
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From:Emerging Infectious Diseases (Vol. 27, Issue 11) Peer-ReviewedWe reconstructed the 2016-2017 Zika virus epidemic in Puerto Rico by using complete genomes to uncover the epidemic's origin, spread, and evolutionary dynamics. Our study revealed that the epidemic was propelled by...
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From:Nature Medicine (Vol. 27, Issue 4) Peer-ReviewedOn 1 August 2018, the Democratic Republic of the Congo (DRC) declared its tenth Ebola virus disease (EVD) outbreak. To aid the epidemiologic response, the Institut National de Recherche Biomédicale (INRB) implemented an...
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From:eLife (Vol. 10) Peer-ReviewedIn 2016/2017, Washington State experienced a mumps outbreak despite high childhood vaccination rates, with cases more frequently detected among school-aged children and members of the Marshallese community. We sequenced...