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From:Emerging Infectious Diseases (Vol. 28, Issue 12) Peer-ReviewedEpidemiologic surveillance of hepatitis E virus in over 300 free-ranging and captive cetaceans in waters off Spain revealed extensive exposure to this pathogen. We suggest the persistent and widespread presence of...
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From:PLoS ONE (Vol. 10, Issue 3) Peer-ReviewedObjective A prospective analysis of the distribution of NK subsets and natural cytotoxicity receptors (NKp30/NKp46) in HIV patients with long-term HAART use and sustained virological and immunological response....
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From:PLoS ONE (Vol. 7, Issue 11) Peer-ReviewedAuthor(s): Antonio Rivero-Juárez 1 , 2 , Luis F. Lopez-Cortes 3 , Angela Camacho 1 , 2 , Almudena Torres-Cornejo 3 , Juan A. Pineda 4 , Manuel Marquez-Solero 5 , Antonio Caruz 6 , Rosa Ruiz-Valderas 3 , Julian...
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From:PLoS ONE (Vol. 12, Issue 5) Peer-ReviewedObjective To evaluate the rate of spontaneous resolution of chronic hepatitis C (CHC) infection in a cohort of HIV-infected patients. Methods A retrospective analysis of 509 HIV-infected patients with chronic...
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From:PLoS ONE (Vol. 9, Issue 7) Peer-ReviewedObjective To establish the role of liver fibrosis as a predictive tool of response to pegylated interferon alpha (Peg-IFN) and ribavirin (RBV) treatment in human immunodeficiency (HIV)/hepatitis C virus (HCV)...
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From:PLoS ONE (Vol. 8, Issue 4) Peer-ReviewedAim To evaluate the influence of the presence of the killer cell immunoglobulin-like receptor (KIR) 3DS1 on HCV treatment response in HIV/HCV genotype 1 co-infected patients Methods HIV/HCV co-infected patients...
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From:PLoS ONE (Vol. 11, Issue 2) Peer-ReviewedObjective To assess the current frequency of ART-associated grade 3-4 transaminase elevations (TE) and grade 4 total bilirubin elevations (TBE) in HIV-infected patients with chronic hepatitis B and/or C, who start a...
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From:PLoS ONE (Vol. 7, Issue 7) Peer-ReviewedBackground The objectives of this study were to evaluate the best position and best exploration probe for determining liver stiffness (LS) in dogs using transient liver elastography (TE). Thirteen dogs were used in...
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From:PLoS ONE (Vol. 8, Issue 7) Peer-ReviewedBackground and Aims Several studies have reported that a significant number of HIV patients not co-infected with HCV/HBV develop liver damage of uncertain origin (LDUO). The objective of our study was to evaluate the...
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From:PLoS ONE (Vol. 9, Issue 4) Peer-ReviewedObjectives: The rs12979860 variant, linked to IL28B gene, predicts sustained viral response (SVR) to pegylated-interferon/ribavirin (pegIFN/RBV) therapy in Hepatitis C Virus genotype 1 or 4 (HCV-1/4)-infected patients....
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From:PLoS ONE (Vol. 12, Issue 11) Peer-ReviewedHepatitis E virus (HEV) is an emerging zoonotic pathogen with pigs and wild boar serving as reservoirs for human infection through direct contact with infected animals or the consumption of raw or undercooked pork...
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From:PLoS ONE (Vol. 14, Issue 8) Peer-ReviewedTreatment guidelines differ in their recommendation to determine baseline resistance associated substitutions (RAS) before starting a first-line treatment with direct-acting antivirals (DAAs). Here we analyze the...
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From:PLoS ONE (Vol. 11, Issue 12) Peer-ReviewedContradictory data about the impact of the rs738409 steatosis-related polymorphism within PNPLA3 gene on liver fibrosis progression in HIV/hepatitis C virus (HIV/HCV)-coinfected patients have been reported. Our...
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From:Journal of the International AIDS Society (Vol. 17) Peer-ReviewedIntroduction: Rilpivirine (RPV) has a better lipid profile than efavirenz (EFV) in naïve patients [1]. Switching to RPV may be convenient for many patients, while maintaining a good immunovirological control [2]. The...
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From:PLoS ONE (Vol. 7, Issue 1) Peer-ReviewedAuthor(s): Luis F. López-Cortés 1 , * , Rosa Ruiz-Valderas 1 , Luis Jimenez-Jimenez 2 , María F. González-Escribano 3 , Almudena Torres-Cornejo 1 , Rosario Mata 1 , Antonio Rivero 4 , Juan A. Pineda 5 , Manuel...