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From:PeerJ (Vol. 9) Peer-ReviewedBackground Hepcidin controls iron homeostasis by inducing the degradation of the iron efflux protein, ferroportin (FPN1), and subsequently reducing serum iron levels. Hepcidin expression is influenced by multiple...
From:PeerJ (Vol. 8) Peer-ReviewedBackground Iron overload is one of common complications of [beta]-thalassemia. Systemic iron homeostasis is regulated by iron-regulatory hormone, hepcidin, which inhibits intestinal iron absorption and iron recycling...
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