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    Academic Journals

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• Complement C3 Facilitates Stratification of Stages of Chronic Hepatitis B and Signifies Development of Acute-on-Chronic Liver Failure in Acute Decompensated Cirrhosis.

  Authors:Chong Chen, Zhu Yuan, Weixia Li, Ling Fei, Liujuan Ji, Qin Huang, et al.From:Advances in Therapy (Vol. 40, Issue 3) Peer-Reviewed

  Mar. 2023522 words Report

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• 3D printing of injury-preconditioned secretome/collagen/heparan sulfate scaffolds for neurological recovery after traumatic brain injury in rats.

  Authors:Xiao-Yin Liu, Zhe-Han Chang, Chong Chen, Jun Liang, Jian-Xin Shi, Xiu Fan, et al.From:Stem Cell Research & Therapy (Vol. 13, Issue 1) Peer-Reviewed

  Dec. 19, 20228,987 words Report 1340LBackground The effects of traumatic brain injury (TBI) can include physical disability and even death. The development of effective therapies to promote neurological recovery is still a challenging problem. 3D-printed...

• Microvascular Burden and Incident Heart Failure Among Middle-Aged and Older Adults With Type 1 or Type 2 Diabetes.

  Authors:Fu-Rong Li, Daniel Nyarko Hukportie, Jing Yang, Huan-Huan Yang, Guo-Chong Chen, and Xian-Bo WuFrom:Diabetes Care (Vol. 45, Issue 12) Peer-Reviewed

  Dec. 2022 Report

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• Unusual bromine enrichment in the gastric mill and setae of the hadal amphipod Hirondellea gigas.

  Authors:Satoshi Okada, Chong Chen, Hiromi Kayama Watanabe, Noriyuki Isobe, and Ken TakaiFrom:PLoS ONE (Vol. 17, Issue 8) Peer-Reviewed

  Aug. 4, 20228,557 words Report 1610LThe hadal amphipod Hirondellea gigas is an emblematic animal of the Pacific trenches, and has a number of special adaptations to thrive in this 'extreme' environment, which includes the deepest part of the Earth's ocean....

• Intratumoral IL-28B Gene Delivery Elicits Antitumor Effects by Remodeling of the Tumor Microenvironment in H22-Bearing Mice.

  Authors:Zhi Li, Jianghua Wang, Chong Chen, Qi He, Xiaoying Xu, Zejiao Da, et al.From:Journal of Immunology Research (Vol. 2022) Peer-Reviewed

  July 28, 20227,493 words Article 1330LIL-28B, belonging to type III interferons (IFN-λ s), exhibits a potent antitumor activity with reduced regulated T cells (Tregs) population, yet the effect of IL-28B on the tumor microenvironment (TME) and if IL-28B can...

• Electrochemical oxidation of pyrogallol: formation and characterization of long-lived oxygen radicals and application to assess the radical scavenging abilities of antioxidants

  Authors:Shaolin Mu and Chong ChenFrom:Journal of Physical Chemistry B (Vol. 116, Issue 41) Peer-Reviewed

  Oct. 18, 2012 Report

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• Deletions linked to TP53 loss drive cancer through p53-independent mechanisms

  Authors:Yu Liu, Chong Chen, Zhengmin Xu, Claudio Scuoppo, Cory D. Rillahan, Jianjiong Gao, et al.From:Nature (Vol. 531, Issue 7595) Peer-Reviewed

  Mar. 24, 20166,797 words Report 1500LMutations disabling the TP53 tumour suppressor gene represent the most frequent events in human cancer and typically occur through a two-hit mechanism involving a missense mutation in one allele and a 'loss of...

• The Effects and Mechanism of Atorvastatin on Pulmonary Hypertension Due to Left Heart Disease

  Authors:Qing Wang, Yi-Zhan Guo, Yi-Tao Zhang, Jiao-Jie Xue, Zhi-Chong Chen, Shi-Yao Cheng, et al.From:PLoS ONE (Vol. 11, Issue 7) Peer-Reviewed

  July 7, 20164,469 words Report 1440LBackground Pulmonary hypertension due to left heart disease (PH-LHD) is one of the most common forms of PH, termed group 2 PH. Atorvastatin exerts beneficial effects on the structural remodeling of the lung in...

• Weaving of biomineralization framework in rotaliid foraminifera: implications for paleoceanographic proxies

  Authors:Yukiko Nagai, Katsuyuki Uematsu, Chong Chen, Ryoji Wani, and Takashi ToyofukuFrom:Biogeosciences (Vol. 15, Issue 22) Peer-Reviewed

  Nov. 14, 2018350 words Author abstract, Bri...

  Elemental and/or isotopic signatures of calcareous tests of foraminifera are commonly used to reconstruct paleoenvironmental conditions. A major problem, often referred to as the vital effect, is that such...

• A Simple Method for Determining the Critical Point of the Soil Water Retention Curve

  Authors:Chong Chen, Kelin Hu, Tusheng Ren, Yin Liang, and Emmanuel ArthurFrom:Soil Science Society of America Journal (Vol. 81, Issue 2) Peer-Reviewed

  March-April 2017226 words Author abstract, Rep...

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• Metformin Induced AMPK Activation, G0/G1 Phase Cell Cycle Arrest and the Inhibition of Growth of Esophageal Squamous Cell Carcinomas In Vitro and In Vivo

  Authors:Xianbin Cai, Xi Hu, Xiaojun Tan, Weijie Cheng, Qinjia Wang, Xiaofeng Chen, et al.From:PLoS ONE (Vol. 10, Issue 7) Peer-Reviewed

  July 21, 20155,824 words Article 1370LEsophageal squamous cell carcinomas (ESCC) have become a severe threat to health and the current treatments for ESCC are frequently not effective. Recent epidemiological studies suggest that the anti-hyperglycemic agent...

• Acupuncture Improved Neurological Recovery after Traumatic Brain Injury by Activating BDNF/TrkB Pathway

  Authors:Xiaohong Li, Chong Chen, Xiping Yang, Jingjing Wang, Ming-liang Zhao, Hongtao Sun, et al.From:Evidence - Based Complementary and Alternative Medicine (Vol. 2017) Peer-Reviewed

  Annual 20174,725 words Article 1380LHow to promote neural repair following traumatic brain injury (TBI) has long been an intractable problem. Although acupuncture has been demonstrated to facilitate the neurological recovery, the underlying mechanism is...

• Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice

  Authors:Yuqing Li, Reha S. Erzurumlu, Chong Chen, Sonal Jhaveri, and Susumu TonegawaFrom:Cell (Vol. 76, Issue 3) Peer-Reviewed

  Feb. 11, 199456 words Article

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• Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice

  Authors:Atsu Aiba, Chong Chen, Karl Herrup, Christian Rosenmund, Charles F. Stevens, and Susumu TonegawaFrom:Cell (Vol. 79, Issue 2) Peer-Reviewed

  Oct. 21, 199465 words Article

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• Transgenic Expression of P1A Induced Thymic Tumor: A Role for Onco-Fetal Antigens in Tumorigenesis

  Authors:Chi-Shan Li, Chong Chen, Pan Zheng, and Yang LiuFrom:PLoS ONE (Vol. 5, Issue 10) Peer-Reviewed

  Oct. 15, 20103,871 words Article 1360LP1A is the first known tumor rejection antigen. It is expressed in embryonic stem cells and multiple tumors but is silent in adult tissues except for the testis and placenta. Therefore, P1A represents a prototype for...

• Hyperexcitable arousal circuits drive sleep instability during aging.

  Authors:Shi-Bin Li, Valentina Martinez Damonte, Chong Chen, Gordon X. Wang, Justus M. Kebschull, Hiroshi Yamaguchi, et al.From:Science (Vol. 375, Issue 6583) Peer-Reviewed

  Feb. 25, 2022660 words Article 1470L

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• Preserved acute pain and reduced neuropathic pain in mice lacking PKC-gamma

  Authors:Annika B. Malmberg, Chong Chen, Susumu Tonegawa, and Allan I. BasbaumFrom:Science (Vol. 278, Issue 5336) Peer-Reviewed

  Oct. 10, 19974,399 words Article In normal animals, peripheral nerve injury produces a persistent, neuropathic pain state in which pain is exaggerated and can be produced by nonpainful stimuli. Here, mice that lack protein kinase C gamma (PKC[Gamma])...

• Estimating the wet-end section of soil water retention curve by using the dry-end section

  Authors:Chong Chen, Kelin Hu, Weidong Li, Gang Wang, and Gang LiuFrom:Soil Science Society of America Journal (Vol. 78, Issue 6) Peer-Reviewed

  November-December 2014248 words Report

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• A Hybrid Clustering and Gradient Descent Approach for Fuzzy Modeling

  Authors:Ching-Chang Wong and Chia-Chong ChenFrom:IEEE Transactions on Systems, Man, and Cybernetics--Part B: Cybernetics (Vol. 29, Issue 6) Peer-Reviewed

  Dec. 1999135 words Article

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• A prediction model for piggery ammonia concentration based on least squares support vector regression using fruit fly optimisation algorithm

  Authors:Chong Chen and Xingqiao LiuFrom:International Journal of Wireless and Mobile Computing (Vol. 17, Issue 1) Peer-Reviewed

  June 29, 2019210 words Article

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