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From:PLoS ONE (Vol. 9, Issue 1) Peer-ReviewedAuthor(s): Roderik F. Viergever 1,2,*, Ghassan Karam 3, Andreas Reis 4, Davina Ghersi 5 Introduction Clinical trials registration is now broadly considered an ethical and scientific responsibility.[1]-[8] In the...
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From:PLoS ONE (Vol. 6, Issue 2) Peer-ReviewedBackground Lack of transparency in clinical trial conduct, publication bias and selective reporting bias are still important problems in medical research. Through clinical trials registration, it should be possible...
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From:PLoS ONE (Vol. 6, Issue 11) Peer-ReviewedBackground In response to growing recognition of the value of prospective registration of systematic review protocols, we planned to develop a web-based open access international register. In order for the register...
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From:PLoS ONE (Vol. 3, Issue 8) Peer-ReviewedBackground The increased use of meta-analysis in systematic reviews of healthcare interventions has highlighted several types of bias that can arise during the completion of a randomised controlled trial. Study...