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• Nuclear factor I/B is an oncogene in small cell lung cancer

  Authors:Alison L. Dooley, Monte M. Winslow, Derek Y. Chiang, Shantanu Banerji, Nicolas Stransky, Talya L. Dayton, et al.From:Genes & Development (Vol. 25, Issue 14) Peer-Reviewed

  July 15, 2011 Report

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• p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

  Authors:Elsa R. Flores, Kenneth Y. Tsai, Denise Crowley, Shomit Sengupta, Annie Yang, Frank McKeon, et al.From:Nature (Vol. 416, Issue 6880) Peer-Reviewed

  Apr. 4, 20024,794 words Article 1370LAuthor(s): Elsa R. Flores [1]; Kenneth Y. Tsai [1, 2]; Denise Crowley [1, 4]; Shomit Sengupta [1, 4]; Annie Yang [3]; Frank McKeon [3]; Tyler Jacks (corresponding author) [1, 4] The tumour-suppressor gene p53 is...

• Ulcerative colitis and autoimmunity induced by loss of myeloid integrins

  Authors:Adam Lacy-Hulbert, Aileen M. Smith, Hamid Tissire, Marc Barry, Denise Crowley, Roderick T. Bronson, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 104, Issue 40) Peer-Reviewed

  Oct. 2, 2007197 words Article

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• A spatially and temporally restricted mouse model of soft tissue sarcoma

  Authors:David G Kirsch, Daniela M Dinulescu, John B Miller, Jan Grimm, Philip M Santiago, Nathan P Young, et al.From:Nature Medicine (Vol. 13, Issue 8) Peer-Reviewed

  Aug. 20075,940 words Article Soft tissue sarcomas are mesenchymal tumors that are fatal in approximately one-third of patients. To explore mechanisms of sarcoma pathogenesis, we have generated a mouse model of soft tissue sarcoma. Intramuscular...

• Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis

  Authors:Alice T. Shaw, Alexander Meissner, James A. Dowdle, Denise Crowley, Margaret Magendantz, Chensi Ouyang, et al.From:Genes & Development (Vol. 21, Issue 6) Peer-Reviewed

  Mar. 15, 200747 words Article

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• Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer

  Authors:Daniela M Dinulescu, Tan A Ince, Bradley J Quade, Sarah A Shafer, Denise Crowley, and Tyler JacksFrom:Nature Medicine (Vol. 11, Issue 1) Peer-Reviewed

  Jan. 20055,642 words Article Epithelial ovarian tumors present a complex clinical, diagnostic and therapeutic challenge because of the difficulty of early detection, lack of known precursor lesions and high mortality rates. Endometrioid ovarian...

• Suppression of lung adenocarcinoma progression by Nkx2-1

  Authors:Monte M. Winslow, Talya L. Dayton, Roel G.W. Verhaak, Caroline Kim-Kiselak, Eric L. Snyder, David M. Feldser, et al.From:Nature (Vol. 473, Issue 7345) Peer-Reviewed

  May 5, 20116,756 words Clinical report 1380LDespite the high prevalence and poor outcome of patients with metastatic lung cancer the mechanisms of tumour progression and metastasis remain largely uncharacterized. Here we modelled human lung adenocarcinoma, which...

• The Nf2 tumor suppressor regulates cell--cell adhesion during tissue fusion

  Authors:Margaret E. McLaughlin, Genevieve M. Kruger, Kelly L. Slocum, Denise Crowley, Norman A. Michaud, Jennifer Huang, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 104, Issue 9) Peer-Reviewed

  Feb. 27, 2007159 words Author abstract, Rep... 60L

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• Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alphav integrins

  Authors:Bernhard L. Bader, Helen Rayburn, Denise Crowley, and Richard O. HynesFrom:Cell (Vol. 95, Issue 4) Peer-Reviewed

  Nov. 13, 199864 words Article

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• Identification of Bronchioalveolar stem cells in normal lung and lung cancer

  Authors:Carla F. Bender Kim, Erica L. Jackson, Amber E. Woolfenden, Imran Babar, Denise Crowley, Tyler Jacks, et al.From:Cell (Vol. 121, Issue 6) Peer-Reviewed

  June 17, 200554 words Article

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• Increased primary tumor growth in mice null for [beta]3- or [beta]3/[beta]5-integrins or selectins

  Authors:Daniela Taverna, Heather Moher, Denise Crowley, Lubor Borsig, Ajit Varki, and Richard O. HynesFrom:Proceedings of the National Academy of Sciences of the United States (Vol. 101, Issue 3) Peer-Reviewed

  Jan. 20, 2004180 words Author abstract

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• Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

  Authors:ERica L. Jackson, Nicholas Willis, Kim Mercer, Roderick T. Bronson, Denise Crowley, Yarmond Montoya, et al.From:Genes & Development (Vol. 15, Issue 24) Peer-Reviewed

  Dec. 15, 200175 words Article

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• Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer

  Authors:Trudy G. Oliver, Kim L. Mercer, Leanne C. Sayles, James R. Burke, Diana Mendus, Katherine S. Lovejoy, et al.From:Genes & Development (Vol. 24, Issue 8) Peer-Reviewed

  Apr. 15, 2010 Report

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• Protein 4.1B suppresses prostate cancer progression and metastasis

  Authors:Sunny Y. Wong, Herbert Haack, Joseph L. Kissil, Marc Barry, Roderick T. Bronson, Steven S. Shen, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 104, Issue 31) Peer-Reviewed

  July 31, 2007144 words Report

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• Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

  Authors:Andrea I. McClatchey, Ichiko Saotome, Kim Mercer, Denise Crowley, James F. Gusella, Roderick T. Bronson, et al.From:Genes & Development (Vol. 12, Issue 8) Peer-Reviewed

  Apr. 15, 199872 words Article

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• Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin

  Authors:Sophie Astrof, Denise Crowley, and Richard O. HynesFrom:Developmental Biology (Vol. 311, Issue 1) Peer-Reviewed

  Nov. 1, 2007293 words Author abstract, Rep...

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• ARF mutation accelerates pituitary tumor development in Rb+/- mice

  Authors:Kenneth Y. Tsai, David MacPherson, Douglas A. Rubinson, Alexander Yu. Nikitin, Roderick Bronson, Kim L. Mercer, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 99, Issue 26) Peer-Reviewed

  Dec. 24, 2002145 words Abstract

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• Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

  Authors:Leisa Johnson, Kim Mercer, Doron Greenbaum, Roderick T. Bronson, Denise Crowley, David A. Tuveson, et al.From:Nature (Vol. 410, Issue 6832) Peer-Reviewed

  Apr. 26, 20014,801 words Article 1490LAuthor(s): Leisa Johnson [1, 2]; Kim Mercer [1, 3]; Doron Greenbaum [1, 4]; Roderick T. Bronson [5]; Denise Crowley [1, 3]; David A. Tuveson [1, 3, 6]; Tyler Jacks (corresponding author) [1, 3] About 30% of human...

• Extensive Vasculogenesis, Angiogenesis, and Organogenesis Precede Lethality in Mice Lacking All [alpha]v Integrins

  Authors:Bernhard L. Bader, Helen Rayburn, Denise Crowley, and Richard O. HynesFrom:Cell (Vol. 95, Issue 4) Peer-Reviewed

  Nov. 13, 1998176 words Report

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• Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

  Authors:Kenneth P. Olive, Roderick T. Bronson, David A. Tuveson, Denise Crowley, Zachary C. Ruhe, Tyler Jacks, et al.From:Cell (Vol. 119, Issue 6) Peer-Reviewed

  Dec. 17, 200452 words Article

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