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From:eLife (Vol. 10) Peer-ReviewedThe cellular adaptive response to hypoxia, mediated by high HIF1[alpha] levels includes metabolic reprogramming, restricted DNA replication and cell division. In contrast to healthy cells, the genome of cancer cells, and...
From:PLoS ONE (Vol. 8, Issue 3) Peer-ReviewedAnticancer role of andrographolide is well documented. To find novel potent derivatives with improved cytotoxicity than andrographolide on cancer cells, two series of di-spiropyrrolidino- and di-spiropyrrolizidino...
From:PLoS ONE (Vol. 10, Issue 3) Peer-ReviewedThe microbial source, which includes live, attenuated, or genetically modified microbes or their cellular component(s) or metabolites, has gained increasing significance for therapeutic intervention against several...
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