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From:Stem Cell Research & Therapy (Vol. 14, Issue 1) Peer-ReviewedBackground Adipose-derived stem cells (ASCs) have been reported to reduce fibrosis in various tissues. In this study, we investigated the inhibitory role of ASCs on capsule formation by analyzing the histologic,...
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From:PLoS ONE (Vol. 13, Issue 9) Peer-ReviewedCartilage tissue engineering typically involves the combination of a biodegradable polymeric support material with chondrocytes. The culture environment in which cell-material constructs are created and stored is an...
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From:Gene Therapy (Vol. 28, Issue 5) Peer-ReviewedSuppressing excessive wound healing responses is critical to ensure surgical success in glaucoma filtration surgery (GFS). Currently used adjunctive materials can lead to side effects due to the nonselectivity in cell...
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From:Journal of Clinical Investigation (Vol. 127, Issue 10) Peer-ReviewedPrimary open-angle glaucoma (POAG) is often caused by elevated intraocular pressure (IOP), which arises due to increased resistance to aqueous humor outflow (AHO). Aqueous humor flows through Schlemm's canal (SC), a...
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From:Nature (Vol. 541, Issue 7636) Peer-ReviewedOesophageal cancers are prominent worldwide; however, there are few targeted therapies and survival rates for these cancers remain dismal. Here we performed a comprehensive molecular analysis of 164 carcinomas of the...
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From:PLoS ONE (Vol. 8, Issue 3) Peer-ReviewedAuthor(s): Do-Young Park 1 , Young-Tae Ahn 1 , Se-Hoon Park 1 , Chul-Sung Huh 1 , * , Sae-Rom Yoo 3 , Rina Yu 2 , 4 , Mi-Kyung Sung 2 , 5 , Robin A. McGregor 2 , Myung-Sook Choi 2 , 3 , * Introduction The...
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From:Journal of Clinical Investigation (Vol. 127, Issue 9) Peer-ReviewedAngiogenesis is a multistep process that requires coordinated migration, proliferation, and junction formation of vascular endothelial cells (ECs) to form new vessel branches in response to growth stimuli. Major...
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From:PLoS ONE (Vol. 16, Issue 4) Peer-ReviewedPurpose To investigate the association between peripheral vasospasm and the visual field (VF) progression rate in patients with normal-tension glaucoma (NTG) with low-teen intraocular pressure (IOP). Methods The...