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    Academic Journals

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• Glycemic Effects and Safety of L-Glutamine Supplementation with or without Sitagliptin in Type 2 Diabetes Patients-A Randomized Study

  Authors:Dorit Samocha-Bonet, Donald J. Chisholm, Fiona M. Gribble, Adelle C. F. Coster, Kevin H. Carpenter, Graham R. D. Jones, et al.From:PLoS ONE (Vol. 9, Issue 11) Peer-Reviewed

  Nov. 20, 20144,606 words Clinical report 1530LBackground and Aims L-glutamine is an efficacious glucagon-like peptide (GLP)-1 secretagogue in vitro. When administered with a meal, glutamine increases GLP-1 and insulin excursions and reduces postprandial...

• Glutamine reduces postprandial glycemia and augments the glucagon-like peptide-1 response in type 2 diabetes patients

  Authors:Dorit Samocha-Bonet, Olivia Wong, Emma-Leigh Synnott, Naomi Piyaratna, Ashley Douglas, Fiona M. Gribble, et al.From:The Journal of Nutrition (Vol. 141, Issue 7) Peer-Reviewed

  July 2011287 words Author abstract, Rep...

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• Short-term overfeeding may induce peripheral insulin resistance without altering subcutaneous adipose tissue macrophages in humans

  Authors:Charmaine S. Tam, Alexander Viardot, Karine Clement, Joan Tordjman, Katherine Tonks, Jerry R. Greenfield, et al.From:Diabetes (Vol. 59, Issue 9) Peer-Reviewed

  Sept. 20105,594 words Report 1480LOBJECTIVE--Chronic low-grade inflammation is a feature of obesity and is postulated to be causal in the development of insulin resistance and type 2 diabetes. The aim of this study was to assess whether overfeeding...

• Food Overconsumption in Healthy Adults Triggers Early and Sustained Increases in Serum Branched-Chain Amino Acids and Changes in Cysteine Linked to Fat Gain

  Authors:Amany K. Elshorbagy, Dorit Samocha-Bonet, Fredrik Jerneren, Cheryl Turner, Helga Refsum, and Leonie K. HeilbronnFrom:The Journal of Nutrition (Vol. 148, Issue 7) Peer-Reviewed

  July 2018 Author abstract, Rep...

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• Overfeeding Reduces Insulin Sensitivity and Increases Oxidative Stress, without Altering Markers of Mitochondrial Content and Function in Humans

  Authors:Dorit Samocha-Bonet, Lesley V. Campbell, Trevor A. Mori, Kevin D. Croft, Jerry R. Greenfield, Nigel Turner, et al.From:PLoS ONE (Vol. 7, Issue 5) Peer-Reviewed

  May 7, 20124,953 words Article 1620LAuthor(s): Dorit Samocha-Bonet 1 , 2 , Lesley V. Campbell 1 , 2 , Trevor A. Mori 3 , Kevin D. Croft 3 , Jerry R. Greenfield 1 , 2 , Nigel Turner 1 , 2 , Leonie K. Heilbronn 1 , 4 , * Introduction Obesity is...

• Effects of intraduodenal glutamine on incretin hormone and insulin release, the glycemic response to an intraduodenal glucose infusion, and antropyloroduodenal motility in health and type 2 diabetes

  Authors:Jessica Chang, Tongzhi Wu, Jerry R. Greenfield, Dorit Samocha-Bonet, Michael Horowitz, and Christopher K. RaynerFrom:Diabetes Care (Vol. 36, Issue 8) Peer-Reviewed

  Aug. 20131,924 words Report 1400LOBJECTIVE--Glutamine reduces postprandial glycemia when given before oral glucose. We evaluated whether this is mediated by stimulation of insulin and/or slowing of gastric emptying. RESEARCH DESIGN AND METHODS--Ten...

• Segregation of a Latent High Adiposity Phenotype in Families with a History of Type 2 Diabetes Mellitus Implicates Rare Obesity-Susceptibility Genetic Variants with Large Effects in Diabetes-Related Obesity

  Authors:Arthur B. Jenkins, Marijka Batterham, Dorit Samocha-Bonet, Katherine Tonks, Jerry R. Greenfield, and Lesley V. CampbellFrom:PLoS ONE (Vol. 8, Issue 8) Peer-Reviewed

  Aug. 7, 20137,289 words Article 1620LBackground We recently reported significantly greater weight gain in non-diabetic healthy subjects with a 1.sup.st degree family history (FH+) of type 2 diabetes mellitus (T2DM) than in a matched control group...

• Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance

  Authors:Daniel J Fazakerley, Rima Chaudhuri, Pengyi Yang, Ghassan J Maghzal, Kristen C Thomas, James R Krycer, et al.From:eLife (Vol. 7) Peer-Reviewed

  Feb. 6, 201827,032 words Report 1610LInsulin resistance in muscle, adipocytes and liver is a gateway to a number of metabolic diseases. Here, we show a selective deficiency in mitochondrial coenzyme Q (CoQ) in insulin-resistant adipose and muscle tissue....