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From:Alzheimer's Research & Therapy (Vol. 12, Issue 1) Peer-ReviewedBackground Plasma neurofilament light (NFL) and total Tau (t-Tau) proteins are candidate biomarkers for early stages of Alzheimer's disease (AD). The impact of biological factors on their plasma concentrations in...
From:PLoS ONE (Vol. 16, Issue 1) Peer-ReviewedThe traditional approach to biomarker discovery for any pathology has been through hypothesis-based research one candidate at a time. The objective of this study was to develop an agnostic approach for the simultaneous...
From:Alzheimer's Research & Therapy (Vol. 12, Issue 1) Peer-Reviewed[beta]-Secretase1 (BACE1) protein concentrations and rates of enzyme activity, analyzed in human bodily fluids, are promising candidate biological markers for guidance in clinical trials investigating BACE1 inhibitors...
From:Alzheimer's Research & Therapy (Vol. 11, Issue 1) Peer-ReviewedAuthor(s): Fatemah A. Sakr1,2 , Michel J. Grothe2 , Enrica Cavedo3,4,5,6,7 , Irina Jelistratova2 , Marie-Odile Habert8,9,10 , Martin Dyrba2 , Gabriel Gonzalez-Escamilla11 , Hugo Bertin9 , Maxime Locatelli8,9,10 ,...
From:Trends in NeurosciencesPeer-ReviewedAbstract Only
From:Future Neurology (Vol. 8, Issue 4) Peer-ReviewedAuthor(s): Enrica Cavedo 1 2 , Annapaola Prestia [*] 3 Keywords * cerebrospinal fluid biomarkers; cognitive decline; dementia; mild cognitive impairment; neuropsychological functions This article reviews the...
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