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From:PLoS ONE (Vol. 7, Issue 9) Peer-ReviewedAuthor(s): Jenny Tigerholm 1 , 2 , * , Sara I. Börjesson 3 , Linnea Lundberg 1 , Fredrik Elinder 3 , Erik Fransén 1 , 2 Introduction Epilepsy is a severe neurological disorder which is characterized by spontaneous...
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From:Chest (Vol. 113, Issue 5) Peer-ReviewedStudy objectives: This study was conducted to evaluate to what extent the cardiopulmonary bypass (CPB) procedure in patients undergoing coronary artery bypass grafting (CABG) contributes to the systemic inflammatory...
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From:Phytomedicine: International Journal of Phytotherapy & Phytopharmacology (Vol. 23, Issue 12) Peer-ReviewedABSTRACT Background: Gloriosa superba L (glory lily, Colchicaceae) contains colchicine, and related alkaloids such as 3-O-demethylcolchicine and its glycoside colchicoside. Previously the in vivo efficacy of a crude...
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From:PLoS ONE (Vol. 12, Issue 1) Peer-ReviewedPurpose Autosomal dominant retinitis pigmentosa (adRP) is characterized by an extensive genetic heterogeneity, implicating 27 genes, which account for 50 to 70% of cases. Here 86 Belgian probands with possible adRP...
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From:Nature (Vol. 420, Issue 6912) Peer-ReviewedAuthor(s): Alexei V. Egorov [1]; Bassam N. Hamam [1]; Erik Fransén [2]; Michael E. Hasselmo [3]; Angel A. Alonso (corresponding author) [1] Working memory represents the ability of the brain to hold externally or...
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From:BMC Research Notes (Vol. 9, Issue 283) Peer-ReviewedBackground In this study we explored the possibility of automating the PGP9.5 immunofluorescence staining assay for the diagnosis of small fiber neuropathy using skin punch biopsies. The laboratory developed test...
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From:Chest (Vol. 116, Issue 5) Peer-ReviewedStudy objectives: This study was conducted to investigate whether intraoperative blood transfusions affect the release of proinflammatory mediators in patients undergoing cardiac surgery. Therefore, we measured plasma...
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From:PLoS ONE (Vol. 9, Issue 2) Peer-ReviewedAuthor(s): Katarzyna Szarc vel Szic 1, Ken Op de Beeck 2,3, Dariusz Ratman 4, An Wouters 3, Ilse M. Beck 5, Ken Declerck 1, Karen Heyninck 6, Erik Fransen 2,7, Marc Bracke 5, Karolien De Bosscher 4, Filip Lardon 3, Guy...
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From:Chest (Vol. 111, Issue 3) Peer-ReviewedStudy objective: Cardiopulmonary bypass (CPB) induces a generalized inflammatory response, including activation of leukocytes, contributing to postoperative morbidity. The inflammatory pathways leading to this systemic...
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From:PLoS ONE (Vol. 9, Issue 8) Peer-ReviewedCutaneous pain sensations are mediated largely by C-nociceptors consisting of both mechano-sensitive (CM) and mechano-insensitive (CMi) fibres that can be distinguished from one another according to their characteristic...
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From:Stem Cell Research & Therapy (Vol. 3, Issue 6) Peer-ReviewedIntroduction Transplantation of neural stem cells (NSCs) is increasingly suggested to become part of future therapeutic approaches to improve functional outcome of various central nervous system disorders. However,...