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    Academic Journals

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• Efforts Made to Eliminate Drug-Resistant Malaria and Its Challenges.

  Authors:Wote Amelo and Eyasu MakonnenFrom:BioMed Research International (Vol. 2021) Peer-Reviewed

  Aug. 30, 202112,385 words Report 1510LSince 2000, a good deal of progress has been made in malaria control. However, there is still an unacceptably high burden of the disease and numerous challenges limiting advancement towards its elimination and ultimate...

• Evaluation of diuretic activity of methanol crude extract of Thymus serrulatus leaves and its solvent fraction in mice

  Authors:Amelework Eshetu Melka, Eyasu Makonnen, Asfaw Debella, Netsanet Fekadu, and Bekesho GeletaFrom:Biology and Medicine (Vol. 8, Issue 7) Peer-Reviewed

  Dec. 20163,794 words Report 1360LAbstract Background: Thymus serrulatus is an indigenous plant to Ethiopia and used widely in the treatment of many illnesses including renal diseases and hypertension. The present study was undertaken to investigate...

• Evaluation of patterns of liver toxicity in patients on antiretroviral and anti-tuberculosis drugs: a prospective four arm observational study in Ethiopian patients

  Authors:Getnet Yimer, Marcus Gry, Wondwossen Amogne, Eyasu Makonnen, Abiy Habtewold, Zelalem Petros, et al.From:PLoS ONE (Vol. 9, Issue 4) Peer-Reviewed

  Apr. 20146,538 words Report 1650LObjectives: To evaluate the incidence, type, severity and predictors of antiretroviral and/or anti-tuberculosis drugs induced liver injury (DILI). Methods: A total of 1,060 treatment naive patients were prospectively...

• Importance of Ethnicity, CYP2B6 and ABCB1 Genotype for Efavirenz Pharmacokinetics and Treatment Outcomes: A Parallel-Group Prospective Cohort Study in Two Sub-Saharan Africa Populations

  Authors:Eliford Ngaimisi, Abiy Habtewold, Omary Minzi, Eyasu Makonnen, Sabina Mugusi, Wondwossen Amogne, et al.From:PLoS ONE (Vol. 8, Issue 7) Peer-Reviewed

  July 5, 20136,847 words Clinical report 1550LObjectives We evaluated the importance of ethnicity and pharmacogenetic variations in determining efavirenz pharmacokinetics, auto-induction and immunological outcomes in two African populations. Methods ART...

• [beta]-defensin genomic copy number is associated with HIV load and immune reconstitution in sub-Saharan African

  Authors:Robert J. Hardwick, Wondwossen Amogne, Sabina Mugusi, Getnet Yimer, Eliford Ngaimisi, Abiy Habtewold, et al.From:Journal of Infectious Diseases (Vol. 206, Issue 7) Peer-Reviewed

  Oct. 1, 2012 Report

   Citation Only

• Pharmacogenetic & Pharmacokinetic Biomarker for Efavirenz Based ARV and Rifampicin Based Anti-TB Drug Induced Liver Injury in TB-HIV Infected Patients

  Authors:Getnet Yimer, Nobuhisa Ueda, Abiy Habtewold, Wondwossen Amogne, Akira Suda, Klaus-Dieter Riedel, et al.From:PLoS ONE (Vol. 6, Issue 12) Peer-Reviewed

  Dec. 6, 20116,016 words Clinical report 1480LBackground Implication of pharmacogenetic variations and efavirenz pharmacokinetics in concomitant efavirenz based antiviral therapy and anti-tubercular drug induced liver injury (DILI) has not been yet studied. We...

• Prevalence and risk factors for efavirenz-based antiretroviral treatment-associated severe vitamin D deficiency: a prospective cohort study

  Authors:Hanna Nylen, Abiy Habtewold, Eyasu Makonnen, Getnet Yimer, Leif Bertilsson, Jurgen Burhenne, et al.From:Medicine (Vol. 95, Issue 34) Peer-Reviewed

  Aug. 23, 2016 Article

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• High Gastrointestinal Colonization Rate with Extended-Spectrum [beta]-Lactamase-Producing Enterobacteriaceae in Hospitalized Patients: Emergence of Carbapenemase-Producing K. pneumoniae in Ethiopia

  Authors:Kassu Desta, Yimtubezinash Woldeamanuel, Aklilu Azazh, Halima Mohammod, Dawit Desalegn, Damte Shimelis, et al.From:PLoS ONE (Vol. 11, Issue 8) Peer-Reviewed

  Aug. 30, 20166,422 words Report 1560LWe investigated the gastrointestinal colonization rate and antibiotic resistance patterns of Extended-Spectrum Beta-Lactamase (ESBL)- producing Escherichia coli and Klebsiella pneumoniae in hospitalized patients...

• Efficacy and Safety of Antiretroviral Therapy Initiated One Week after Tuberculosis Therapy in Patients with CD4 Counts < 200 Cells/[mu]L: TB-HAART Study, a Randomized Clinical Trial

  Authors:Wondwossen Amogne, Getachew Aderaye, Abiy Habtewold, Getnet Yimer, Eyasu Makonnen, Alemayhu Worku, et al.From:PLoS ONE (Vol. 10, Issue 5) Peer-Reviewed

  May 12, 20156,827 words Clinical report 1500LBackground Given the high death rate the first two months of tuberculosis (TB) therapy in HIV patients, it is critical defining the optimal time to initiate combination antiretroviral therapy (cART). Methods A...

• Toxicological study of the butanol fractionated root extract of Asparagus africanus Lam., on some blood parameter and histopathology of liver and kidney in mice

  Authors:Sintayehu Kebede, Mekbeb Afework, Asfaw Debella, Wondwossen Ergete, and Eyasu MakonnenFrom:BMC Research Notes (Vol. 9, Issue 48) Peer-Reviewed

  Jan. 27, 20165,179 words Report 1610LBackground The butanol fractionated root extract of Lam., a traditional herb widely used to treat various ailments were analyzed for the presence of potential toxicity after single (acute) and repeated...

• Prevalence and risk factors for efavirenz-based antiretroviral treatment-associated severe vitamin D deficiency: A prospective cohort study.

  Authors:Hanna NylȨn, Abiy Habtewold, Eyasu Makonnen, Getnet Yimer, Leif Bertilsson, Jȭrgen Burhenne, et al.From:Medicine (Vol. 95, Issue 32) Peer-Reviewed

  Aug. 1, 2016423 words Report, Author abstr...

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• Toxicological investigation of acute and chronic treatment with Gnidia stenophylla Gilg root extract on some blood parameters and histopathology of spleen, liver and kidney in mice

  Authors:Tilahun Alemayehu Nigatu, Mekbeb Afework, Kelbessa Urga, Wondwossen Ergete, and Eyasu MakonnenFrom:BMC Research Notes (Vol. 10, Issue 1) Peer-Reviewed

  Nov. 28, 20177,698 words Article 1540LBackground In southeast Ethiopia, people locally use the roots of Gnidia stenophylla Gilg (Thymelaeaceae) to cure malaria and other diseases with no literature evidence substantiating its safety. The aim of this...

• Is there a need to increase the dose of efavirenz during concomitant rifampicin-based antituberculosis therapy in sub-Saharan Africa? The HIV-TB pharmagene study

  Authors:Abiy Habtewold, Eyasu Makonnen, Wondwossen Amogne, Getnet Yimer, Getachew Aderaye, Leif Bertilsson, et al.From:Pharmacogenomics (Vol. 16, Issue 10) Peer-Reviewed

  July 20159,462 words Report 1810LAuthor(s): Abiy Habtewold aff1 aff2 , Eyasu Makonnen aff2 , Wondwossen Amogne aff3 aff4 , Getnet Yimer aff1 aff2 , Getachew Aderaye aff3 , Leif Bertilsson aff1 , Jürgen Burhenne aff5 , Eleni Aklillu [*] aff1 Keywords...

• Anti-Tuberculosis Therapy-Induced Hepatotoxicity among Ethiopian HIV-Positive and Negative Patients

  Authors:Getnet Yimer, Getachew Aderaye, Wondwossen Amogne, Eyasu Makonnen, Eleni Aklillu, Lars Lindquist, et al.From:PLoS ONE (Vol. 3, Issue 3) Peer-Reviewed

  Mar. 19, 20083,971 words Article 1700LBackground To assess and compare the prevalence, severity and prognosis of anti-TB drug induced hepatotoxicity (DIH) in HIV positive and HIV negative tuberculosis (TB) patients in Ethiopia. Methodology/Principal...

• [beta]-defensin genomic copy number is associated with HIV load and immune reconstitution in sub-Saharan Africans

  Authors:Robert J. Hardwick, Wondwossen Amogne, Sabina Mugusi, Getnet Yimer, Eliford Ngaimisi, Abiy Habtewold, et al.From:Journal of Infectious Diseases (Vol. 206, Issue 7) Peer-Reviewed

  Oct. 1, 2012 Report

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• Essential oils as topical anti-infective agents: A systematic review and meta-analysis.

  Authors:Serawit Deyno, Andrew G. Mtewa, Abiy Abebe, Ariya Hymete, Eyasu Makonnen, Joel Bazira, et al.From:Complementary Therapies in Medicine (Vol. 47)

  Dec. 2019564 words Report

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