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From:Diabetes (Vol. 55, Issue 8) Peer-ReviewedRecombinant human IGF-I (rhIGF-I) complexed with its natural binding protein IGF-binding protein (IGFBP)-3 (rhIGF-I/IGFBP-3) is a novel formulation that has been shown to improve insulin sensitivity in type 1 diabetes,...
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From:Diabetes (Vol. 55, Issue 2) Peer-ReviewedHeterozygous mutations in the transcription factors hepatocyte nuclear factor (HNF)-1[alpha] and -1[beta] result in MODY (maturity-onset diabetes of the young). Despite structural similarity between HNF-1[alpha] and...
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From:Diabetes Care (Vol. 34, Issue 7) Peer-ReviewedOBJECTIVE--Insulin detemir lacks the usual propensity for insulin to cause weight gain. We investigated whether this effect was a result of reduced energy intake and/or increased energy expenditure. RESEARCH DESIGN...
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From:Diabetes (Vol. 62, Issue 12) Peer-ReviewedThe aim was to determine whether fed VLDL and chylomicron (CM) triacylglycerol (TAG) production rates are elevated in metabolic syndrome (MetS). Eight men with MetS (BMI 29.7 [+ or -] 1.1) and eight lean age-matched...
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From:Diabetes (Vol. 63, Issue 2) Peer-ReviewedPrandial Hypertriglyceridemia in Metabolic Syndrome Is Due to an Overproduction of Both Chylomicron and VLDL Triacylglycerol. Diabetes 2013;62:4063-4069 DOI: 10.2337/db14-er02a In the Acknowledgments of the...
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From:Diabetes Care (Vol. 23, Issue 8) Peer-ReviewedStudies with a covalently linked thyroxyl-insulin complex in humans OBJECTIVE -- To test whether a thyroxyl-insulin analog with restricted access to receptor sites in peripheral tissues displays relative...
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From:PLoS ONE (Vol. 16, Issue 3) Peer-ReviewedThe objective of the study was to assess associations of the rs9939609 FTO allele to glucose tolerance, hepatic and total insulin sensitivity (IS) in individuals with obesity. From a low-dose hyperinsulinemic euglycemic...