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    Academic Journals

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• Glucose-6-phosphate dehydrogenase blockade potentiates tyrosine kinase inhibitor effect on breast cancer cells through autophagy perturbation.

  Authors:Luigi Mele, Marcella la Noce, Francesca Paino, Tarik Regad, Sarah Wagner, Davide Liccardo, et al.From:Journal of Experimental & Clinical Cancer Research (Vol. 38, Issue 1) Peer-Reviewed

  Apr. 12, 20196,824 words Article 1430LBackground Glucose-6-phospate dehydrogenase (G6PD) is the limiting enzyme of the pentose phosphate pathway (PPP) correlated to cancer progression and drug resistance. We previously showed that G6PD inhibition leads to...

• HDAC2 depletion promotes osteosarcoma's stemness both in vitro and in vivo: a study on a putative new target for CSCs directed therapy

  Authors:Marcella La Noce, Francesca Paino, Luigi Mele, Gianpaolo Papaccio, Tarik Regad, Angela Lombardi, et al.From:Journal of Experimental & Clinical Cancer Research (Vol. 37, Issue 1) Peer-Reviewed

  Dec. 3, 201813,916 words Report 1490LBackground Cancer stem cells (CSCs) play a key role in cancer initiation, progression and chemoresistance. Epigenetic alterations have been identified as prominent factors that contribute to the CSCs phenotype. Here,...

• Epithelial to Mesenchymal Transition by TGF[beta]-1 Induction Increases Stemness Characteristics in Primary Non Small Cell Lung Cancer Cell Line

  Authors:Giuseppe Pirozzi, Virginia Tirino, Rosa Camerlingo, Renato Franco, Aantonello La Rocca, Eleonora Liguori, et al.From:PLoS ONE (Vol. 6, Issue 6) Peer-Reviewed

  June 30, 20116,891 words Article 1520LBackground Cancer Stem Cells (CSCs) hypothesis asserts that only a small subset of cells within a tumour is capable of both tumour initiation and sustainment. The Epithelial-Mesenchymal Transition (EMT) is an...

• Human Dental Pulp Stem Cells Hook into Biocoral Scaffold Forming an Engineered Biocomplex

  Authors:Carlo Mangano, Francesca Paino, Riccardo d'Aquino, Alfredo De Rosa, Giovanna Iezzi, Adriano Piattelli, et al.From:PLoS ONE (Vol. 6, Issue 4) Peer-Reviewed

  Apr. 11, 20115,421 words Article 1520LThe aim of this study was to evaluate the behavior of human Dental Pulp Stem Cells (DPSCs), as well as human osteoblasts, when challenged on a Biocoral scaffold, which is a porous natural hydroxyapatite. For this...