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From:PLoS ONE (Vol. 16, Issue 8) Peer-ReviewedInfluenza is a highly contagious viral respiratory disease that affects million of people worldwide each year. Annual vaccination is recommended by the World Health Organization with the goal of reducing influenza...
From:PLoS ONE (Vol. 16, Issue 2) Peer-ReviewedRecent advances in high-throughput single cell sequencing have opened up new avenues into the investigation of B cell receptor (BCR) repertoires. In this study, PBMCs were collected from 17 human participants vaccinated...
From:Journal of Immunology ResearchPeer-ReviewedVaccines represent the most effective prophylactic strategy in our arsenal for controlling the spread of infectious diseases and have increased human life expectancy. As an example, the eradication of smallpox and the...
From:PLoS ONE (Vol. 12, Issue 1) Peer-ReviewedA paradox in monoclonal antibody (mAb) therapy is that despite the well-documented tolerogenic properties of deaggregated IgG, most therapeutic IgG mAb induce anti-mAb responses. To analyze CD4 T cell reactions against...
From:Proceedings of the National Academy of Sciences of the United States (Vol. 112, Issue 1) Peer-ReviewedAbstract Only
From:Journal of Immunology Research (Vol. 2017) Peer-ReviewedThe domestic ferret (Mustela putorius furo) serves as an animal model for the study of several viruses that cause human disease, most notably influenza. Despite the importance of this animal model, characterization of...
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