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From:PLoS ONE (Vol. 16, Issue 2) Peer-ReviewedBackground Several studies have highlighted both the extreme anticancer effects of Cryptotanshinone (CT), a Stat3 crippling component from Salvia miltiorrhiza, as well as other STAT3 inhibitors to fight cancer....
From:PLoS ONE (Vol. 15, Issue 8) Peer-ReviewedIntroduction Nucleosomes consist of small fragments of DNA wrapped around a histone octamer core. Diseases such as cancer or inflammation lead to cell death, which causes fragmentation and release of nucleosomes into...
From:PLoS ONE (Vol. 11, Issue 2) Peer-ReviewedDevelopment of iniparib as an anti-cancer agent was hindered in part by lingering questions regarding its mechanism of action, the activity of its metabolites, and their potential accumulation in tumors. Due to strong...
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