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    Academic Journals

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• Beyond gut instincts: Microbe survival depends on sugars and butyrate.

  Author:Huiying LiFrom:Cell (Vol. 185, Issue 3) Peer-Reviewed

  Feb. 3, 202282 words Brief article

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• The organizational relationship-based political connection and debt financing: Evidence from Chinese private firms.

  Authors:Nan Zhang, Qiaozhuan Liang, Huiying Li, and Xiao WangFrom:Bulletin of Economic Research (Vol. 74, Issue 1) Peer-Reviewed

  Jan. 2022144 words Report, Brief articl...

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• Pulsed electron paramagnetic resonance study of domain docking in neuronal nitric oxide synthase: the calmodulin and output state perspective

  Authors:Andrei V. Astashkin, Li Chen, Xixi Zhou, Huiying Li, Thomas L. Poulos, Ke Jian Liu, et al.From:Journal of Physical Chemistry A (Vol. 118, Issue 34) Peer-Reviewed

  Aug. 28, 2014 Report

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• Identifying genetic diversity of O antigens in Aeromonas hydrophila for molecular serotype detection

  Authors:Hengchun Cao, Min Wang, Qian Wang, Tingting Xu, Yuhui Du, Huiying Li, et al.From:PLoS ONE (Vol. 13, Issue 9) Peer-Reviewed

  Sept. 5, 20187,609 words Report 1520LAeromonas hydrophila is a globally occurring, potentially virulent, gram-negative opportunistic pathogen that is known to cause water and food-borne diseases around the world. In this study, we use whole genome...

• Photochemical reactions of substituted cyclopropenium salts

  Authors:Huiying Li, Kangtai Ren, and Douglas C. NeckersFrom:Journal of Organic Chemistry (Vol. 66, Issue 25) Peer-Reviewed

  Dec. 14, 200138 words Article

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• Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase inhibitors

  Authors:Haitao Ji, Benjamin Z. Stanton, Jotaro Igarashi, Huiying Li, Pavel Martasek, Linda J. Roman, et al.From:Journal of the American Chemical Society (Vol. 130, Issue 12) Peer-Reviewed

  Mar. 26, 200842 words Article

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• A network pharmacology approach to determine active compounds and action mechanisms of Ge-Gen-Qin-Lian decoction for treatment of type 2 diabetes

  Authors:Huiying Li, Linhua Zhao, Bo Zhang, Yuyu Jiang, Xu Wang, Yun Guo, et al.From:Evidence - Based Complementary and Alternative Medicine (Vol. 2014) Peer-Reviewed

  Annual 20146,941 words Clinical report 1490LTraditional Chinese medicine (TCM) herbal formulae can be valuable therapeutic strategies and drug discovery resources. However, the active ingredients and action mechanisms of most TCM formulae remain unclear....

• Detection of parallel functional modules by comparative analysis of genome sequences

  Authors:Huiying Li, Matteo Pellegrini, and David EisenbergFrom:Nature Biotechnology (Vol. 23, Issue 2) Peer-Reviewed

  Feb. 20056,578 words Article Parallel functional modules are separate sets of proteins in an organism that catalyze the same or similar biochemical reactions but act on different substrates or use different cofactors. They originate by gene...

• Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-Nitroarginine-containing dipeptide inhibitors bound

  Authors:Mack Flinspach, Huiying Li, Joumana Jamal, Weiping Yang, Richard B., and Thomas L. PoulosFrom:Biochemistry (Vol. 43, Issue 18) Peer-Reviewed

  May 11, 200442 words Article

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• Methylated [N.sup.omega]-hydroxy-l-arginine analogues as mechanistic probes for the second step of the nitric oxide synthase-catalyzed reaction

  Authors:Kristin Jansen Labby, Huiying Li, Linda J. Roman, Pavel Martasek, Thomas L. Poulos, and Richard B. SilvermanFrom:Biochemistry (Vol. 52, Issue 18) Peer-Reviewed

  May 7, 201379 words Report

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• Communication between the zinc and tetrahydrobiopterin binding sites in nitric oxide synthased

  Authors:Georges Chreifi, Colin J. Suckling, Colin L. Gibson, Craig R. McInnes, Huiying Li, and Thomas L. PoulosFrom:Biochemistry (Vol. 53, Issue 25) Peer-Reviewed

  July 1, 201470 words Report

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• TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells

  Authors:Stephan R Krutzik, Belinda Tan, Huiying Li, Maria Teresa Ochoa, Philip T Liu, Sarah E Sharfstein, et al.From:Nature Medicine (Vol. 11, Issue 6) Peer-Reviewed

  June 20056,386 words Article Leprosy enables investigation of mechanisms by which the innate immune system contributes to host defense against infection, because in one form, the disease progresses, and in the other, the infection is limited. We...

• Nonspecific dizziness as an unusual presentation of neurocysticercosis: A case report

  Authors:Huiying Li, Jing Sun, and Guangxian NanFrom:Medicine (Vol. 98, Issue 30) Peer-Reviewed

  July 2019176 words Author abstract, Cli...

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• Enhancement of the HIF-1[alpha]/15-LO/15-HETE Axis Promotes Hypoxia-Induced Endothelial Proliferation in Preeclamptic Pregnancy

  Authors:Dandan Yuan, Yajuan Ran, Qian Liu, Yanhua Zhang, Huiying Li, Peiling Li, et al.From:PLoS ONE (Vol. 9, Issue 5) Peer-Reviewed

  May 5, 20146,468 words Article 1330LPreeclampsia (PE) is an extremely serious condition in pregnant women and the leading cause of maternal and fetal morbidity and mortality. Despite active research, the etiological factors of this disorder remain...

• Structural basis for effector control and redox partner recognition in Cytochrome p450

  Authors:Sarvind Tripathi, Huiying Li, and Thomas L. PoulosFrom:Science (Vol. 340, Issue 6137) Peer-Reviewed

  June 7, 2013140 words Author abstract, Rep...

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• Knockdown of Nrf2 inhibits angiogenesis by downregulating VEGF expression through PI3K/Akt signaling pathway in cerebral microvascular endothelial cells under hypoxic conditions

  Authors:Yujing Huang, Ying Mao, Huiying Li, Guangxun Shen, and Guangxian NanFrom:Biochemistry and Cell Biology (Vol. 96, Issue 4) Peer-Reviewed

  Aug. 20185,473 words Report 1530LIschemic stroke is a major cerebrovascular disease resulting from a transient or permanent local reduction of cerebral blood flow. Angiogenesis plays an important role in cerebral microvascular repair after ischemic...

• Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism

  Authors:C. S. Raman, Huiying Li, Pavel Martasek, Garry Southan, Bettie Sue S. Masters, and Thomas L. PoulosFrom:Biochemistry (Vol. 40, Issue 45) Peer-Reviewed

  Nov. 13, 200150 words Article

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• Use of genetic profiting in leprosy to discriminate clinical forms of the disease

  Authors:Joshua R. Bleharski, Huiying Li, Christoph Meinken, Thomas G. Graeber, Maria-Teresa Ochoa, Masahiro Yamamura, et al.From:Science (Vol. 301, Issue 5639) Peer-Reviewed

  Sept. 12, 20032,422 words Article Leprosy presents as a clinical and immunological spectrum of disease. With the use of gene expression profiling, we observed that a distinction in gene expression correlates with and accurately classifies the clinical...

• The Toxic Effects of Aflatoxin B1 and Aflatoxin Ml on Kidney through Regulating L-Proline and Downstream Apoptosis.

  Authors:Huiying Li, Lei Xing, Muchen Zhang, Jiaqi Wang, and Nan ZhengFrom:BioMed Research International (Vol. 2018) Peer-Reviewed

  Annual 20186,297 words Article 1530LThe toxic effects and potential mechanisms of aflatoxin B1 (AFB1), aflatoxin M1 (AFM1), and AFB1+AFM1 in the kidney were studied and compared in HEK 293 cells model and CD-1 mice model. The 35-day subacute toxicity mice...

• The combination of lactoferrin and linolenic acid inhibits colorectal tumor growth through activating AMPK/JNK-related apoptosis pathway.

  Authors:Qianqian Yao, Huiying Li, Linlin Fan, Shengnan Huang, Jiaqi Wang, and Nan ZhengFrom:PeerJ (Vol. 9) Peer-Reviewed

  May 31, 20217,220 words Article 1510LColorectal cancer is a common cause of death with few available therapeutic strategies, and the preventative complexes in adjunctive therapy are urgently needed. Increasing evidences have shown that natural ingredients,...