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    Academic Journals

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• Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells

  Authors:Herbert G Kasler, Intelly S Lee, Hyung W Lim, and Eric VerdinFrom:eLife (Vol. 7) Peer-Reviewed

  Apr. 17, 201822,288 words Report 1660LWe report that Histone Deacetylase 7 (HDAC7) controls the thymic effector programming of Natural Killer T (NKT) cells, and that interference with this function contributes to tissue-specific autoimmunity. Gain of HDAC7...

• Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity

  Authors:Kotaro Shirakawa, Lan Wang, Na Man, Jasna Maksimoska, Alexander W Sorum, Hyung W Lim, et al.From:eLife (Vol. 5) Peer-Reviewed

  May 31, 201613,139 words Report 1530LSalicylate and acetylsalicylic acid are potent and widely used anti-inflammatory drugs. They are thought to exert their therapeutic effects through multiple mechanisms, including the inhibition of cyclo-oxygenases,...