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From:Journal of Clinical Investigation (Vol. 132, Issue 3) Peer-ReviewedBitter taste receptors (taste 2 receptors, TAS2Rs) serve as warning sensors in the lingual system against the ingestion of potentially poisonous food. Here, we investigated the functional role of TAS2Rs in the human gut...
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From:eLife (Vol. 6) Peer-ReviewedParkinson's disease (PD) is a neurodegenerative disease with motor and non-motor symptoms, including constipation. Therefore, several studies have investigated the gastrointestinal tract, and more specifically the...
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From:Proceedings of the National Academy of Sciences of the United States (Vol. 108, Issue 5) Peer-ReviewedAbstract Only
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From:Expert Review of Gastroenterology & Hepatology (Vol. 6, Issue 5) Peer-ReviewedAuthor(s): Ege Altan 1 , Tatsuhiro Masaoka 1 , Ricard Farré 1 , Jan Tack [*] 1 Keywords : acotiamide; early satiation; functional dyspepsia; gastric accommodation; gastric emptying; postprandial fullness;...
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From:Expert Review of Gastroenterology & Hepatology (Vol. 7, Issue 5s1) Peer-ReviewedAuthor(s): Jan Tack [*] 1 Keywords : abdominal pain; bloating; constipation; European Medicines Agency; gender; irritable bowel syndrome; linaclotide; quality of life Patients with irritable bowel syndrome...
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From:PLoS ONE (Vol. 9, Issue 5) Peer-ReviewedBackground and Aims Recent reports indicate the presence of low grade inflammation in functional gastrointestinal disorders (FGID), in these cases often called "post-inflammatory" FGIDs. However, suitable animal...