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From:Epigenetics & Chromatin (Vol. 8, Issue 1) Peer-ReviewedBackground Precise nucleosome positioning is an increasingly recognized feature of promoters and enhancers, reflecting complex contributions of DNA sequence, nucleosome positioning, histone modification and...
From:Science (Vol. 293, Issue 5538) Peer-ReviewedSLAP-130/Fyb (SLP-76-associated phosphoprotein or Fyn-binding protein; also known as Fyb/Slap) is a hematopoietic-specific adapter, which associates with and modulates function of SH2-containing leukocyte phosphoprotein...
From:Nature Medicine (Vol. 21, Issue 12) Peer-ReviewedHuman cancer genome sequencing has recently revealed that genes that encode subunits of SWI/SNF chromatin remodeling complexes are frequently mutated across a wide variety of cancers, and several subunits of the complex...
From:Nature Medicine (Vol. 21, Issue 12) Peer-ReviewedThe authors identify EZH2 as a general underlying dependency of tumors with mutations in the SWI/SNF chromatin regulator complex, and they show that EZH2's pro-tumorigenic role may be dependent on non-catalytic...
From:Proceedings of the National Academy of Sciences of the United States (Vol. 95, Issue 20) Peer-ReviewedAbstract Only
From:Cancer (Vol. 120, Issue 6) Peer-ReviewedCitation Only
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