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    Academic Journals

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• Aducanumab: look before leaping.

  Author:Joel S. PerlmutterFrom:Nature Medicine (Vol. 27, Issue 9) Peer-Reviewed

  Sept. 2021846 words Article 1510L

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• Revisiting FDA Approval of Aducanumab.

  Authors:G. Caleb Alexander, David S. Knopman, Scott S. Emerson, Bruce Ovbiagele, Richard J. Kryscio, Joel S. Perlmutter, et al.From:The New England Journal of Medicine (Vol. 385, Issue 9) Peer-Reviewed

  Aug. 26, 202151 words Article

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• Levodopa-Responsive Hemiparkinsonism Secondary to Cystic Expansion from a Coiled Cerebral Aneurysm

  Authors:Scott A. Norris, Colin P. Derdeyn, and Joel S. PerlmutterFrom:Journal of Neuroimaging (Vol. 25, Issue 2) Peer-Reviewed

  March-April 201571 words Report

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• A possible substrate for dopamine-related changes in mood and behavior: prefrontal and limbic effects of a D3-preferring dopamine agonist

  Authors:Kevin J. Black, Tamara Hershey, Jonathan M. Koller, Tom O. Videen, Mark A. Mintun, Joseph L. Price, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 99, Issue 26) Peer-Reviewed

  Dec. 24, 2002237 words Abstract

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• [11C]dihydrotetrabenazine Positron Emission Tomography in Manganese-Exposed Workers.

  Authors:Susan R. Criswell, Susan Searles Nielsen, Mark N. Warden, Joel S. Perlmutter, Stephen M. Moerlein, Lianne Sheppard, et al.From:Journal of Occupational and Environmental Medicine (Vol. 62, Issue 10) Peer-Reviewed

  Oct. 2020288 words Brief article

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• Basal ganglia intensity indices and diffusion weighted imaging in manganese-exposed welders

  Authors:Susan R. Criswell, Joel S. Perlmutter, John L. Huang, Nima Golchin, Hubert P. Flores, Angela Hobson, et al.From:Occupational and Environmental Medicine (Vol. 69, Issue 5) Peer-Reviewed

  May 2012 Report

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• Additive global cerebral blood flow normalization in arterial spin labeling perfusion imaging

  Authors:Stephanie B. Stewart, Jonathan M. Koller, Meghan C. Campbell, Joel S. Perlmutter, and Kevin J. BlackFrom:PeerJ (Vol. 3) Peer-Reviewed

  Mar. 17, 20154,297 words Article 1490LTo determine how different methods of normalizing for global cerebral blood flow (gCBF) affect image quality and sensitivity to cortical activation, pulsed arterial spin labeling (pASL) scans obtained during a visual...

• Basal ganglia intensity indices and diffusion weighted imaging in manganese-exposed welders

  Authors:Susan R Criswell, Joel S Perlmutter, John L Huang, Nima Golchin, Hubert P Flores, Angela Hobson, et al.From:Occupational and Environmental Medicine (Vol. 69, Issue 6) Peer-Reviewed

  June 2012 Article

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• Research paper: Psychiatric associations of adult-onset focal dystonia phenotypes

  Authors:Brian D Berman, Johanna Junker, Erika Shelton, Stefan H Sillau, H A Jinnah, Joel S Perlmutter, et al.From:Journal of Neurology, Neurosurgery and Psychiatry (Vol. 88, Issue 7) Peer-Reviewed

  July 2017 Report

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• Binding of the Radioligand SIL23 to [alpha]-Synuclein Fibrils in Parkinson Disease Brain Tissue Establishes Feasibility and Screening Approaches for Developing a Parkinson Disease Imaging Agent

  Authors:Devika P. Bagchi, Lihai Yu, Joel S. Perlmutter, Jinbin Xu, Robert H. Mach, Zhude Tu, et al.From:PLoS ONE (Vol. 8, Issue 2) Peer-Reviewed

  Feb. 6, 201310,152 words Article 1620LAccumulation of [alpha]-synuclein ([alpha]-syn) fibrils in Lewy bodies and Lewy neurites is the pathological hallmark of Parkinson disease (PD). Ligands that bind [alpha]-syn fibrils could be utilized as imaging agents...

• Validation of diffusion tensor imaging measures of nigrostriatal neurons in macaques

  Authors:Joshua S. Shimony, Jerrel Rutlin, Morvarid Karimi, Linlin Tian, Abraham Z. Snyder, Susan K. Loftin, et al.From:PLoS ONE (Vol. 13, Issue 9) Peer-Reviewed

  Sept. 5, 20186,326 words Report 1530LObjective Interpretation of diffusion MRI in the living brain requires validation against gold standard histological measures. We compared diffusion values of the nigrostriatal tract to PET and histological results...

• No Differential Regulation of Dopamine Transporter (DAT) and Vesicular Monoamine Transporter 2 (VMAT2) Binding in a Primate Model of Parkinson Disease

  Authors:LinLin Tian, Morvarid Karimi, Susan K. Loftin, Chris A. Brown, HuChuan Xia, JinBin Xu, et al.From:PLoS ONE (Vol. 7, Issue 2) Peer-Reviewed

  Feb. 16, 20125,699 words Article 1470LAuthor(s): LinLin Tian 1 , Morvarid Karimi 1 , Susan K. Loftin 1 , Chris A. Brown 1 , HuChuan Xia 1 , JinBin Xu 2 , Robert H. Mach 2 , Joel S. Perlmutter 1 , 2 , 3 , 4 , 5 , * Introduction Selective degeneration...

• Neuroimaging Analysis of the Dopamine Basis for Apathetic Behaviors in an MPTP-Lesioned Primate Model

  Authors:LinLin Tian, Yuanxuan Xia, Hubert P. Flores, Meghan C. Campbell, Stephen M. Moerlein, and Joel S. PerlmutterFrom:PLoS ONE (Vol. 10, Issue 7) Peer-Reviewed

  July 2, 20157,026 words Article 1560LApathy commonly occurs in Parkinson disease (PD) patients; however, the role of dopamine in the pathophysiology of apathy remains elusive. We previously demonstrated that dopaminergic dysfunction within the ventral...

• Perception of active and passive turning in Parkinson disease

  Authors:Gammon M. Earhart, Elizabeth S. Stevens, Joel S. Perlmutter, and Minna HongFrom:Neurorehabilitation and Neural Repair (Vol. 21, Issue 2) Peer-Reviewed

  June 20074,455 words Article 1660LBackground. Many individuals with Parkinson disease (PD) experience difficulty with turning, yet little is known about the reasons for this difficulty. Objective. The authors sought to determine whether individuals with...

• Neuroinflammation and Myelin Status in Alzheimer's Disease, Parkinson's Disease, and Normal Aging Brains: A Small Sample Study

  Authors:Fei Han, Richard J. Perrin, Qing Wang, Yong Wang, Joel S. Perlmutter, John C. Morris, et al.From:Parkinson's DiseasePeer-Reviewed

  July 31, 20194,548 words Article 1460LMicroglia and astrocytes play important roles in mediating the immune processes and nutritional support in the central nervous system (CNS). Neuroinflammation has been indicated in the progression of neurodegenerative...

• Sweet dopamine: sucrose preferences relate differentially to striatal D2 receptor binding and age in obesity

  Authors:Marta Y. Pepino, Sarah A. Eisenstein, Allison N. Bischoff, Samuel Klein, Stephen M. Moerlein, Joel S. Perlmutter, et al.From:Diabetes (Vol. 65, Issue 9) Peer-Reviewed

  Sept. 2016 Report

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• Deep brain stimulation

  Authors:Joel S. Perlmutter and Jonathan W. MinkFrom:Annual Review of Neuroscience (Vol. 29) Peer-Reviewed

  Annual 200645 words Article

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• Insulin, Central Dopamine D2 Receptors, and Monetary Reward Discounting in Obesity

  Authors:Sarah A. Eisenstein, Danuta M. Gredysa, Jo Ann Antenor-Dorsey, Leonard Green, Ana Maria Arbelaez, Jonathan M. Koller, et al.From:PLoS ONE (Vol. 10, Issue 7) Peer-Reviewed

  July 20, 201510,372 words Article 1710LAnimal research finds that insulin regulates dopamine signaling and reward behavior, but similar research in humans is lacking. We investigated whether individual differences in body mass index, percent body fat,...

• Transient acute depression induced by high-frequency deep-brain stimulation

  Authors:Marcio L.S. Bezerra, J.-Victor L. Martinez, Jose A. Nasser, Rajeev Kumar, Paul Krack, Pierre Pollak, et al.From:The New England Journal of Medicine (Vol. 341, Issue 13) Peer-Reviewed

  Sept. 23, 1999 Letter to the editor

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• Correction: Insulin, Central Dopamine D2 Receptors, and Monetary Reward Discounting in Obesity

  Authors:Sarah A. Eisenstein, Danuta M. Gredysa, Jo Ann Antenor-Dorsey, Leonard Green, Ana Maria Arbelaez, Jonathan M. Koller, et al.From:PLoS ONE (Vol. 11, Issue 1) Peer-Reviewed

  Jan. 8, 2016133 words Brief article, Corre... 1650LAuthor(s): Sarah A. Eisenstein, Danuta M. Gredysa, Jo Ann Antenor-Dorsey, Leonard Green, Ana Maria Arbeláez, Jonathan M. Koller, Kevin J. Black, Joel S. Perlmutter, Stephen M. Moerlein, Tamara Hershey The following...