Search Results

• • 36 

    Academic Journals

  • Sort by: sorttype.publication.date.desc Newest sorttype.publication.date.asc Oldest sorttype.relevance Relevance

• The evolving role of germline genetic testing and management in prostate cancer: Report from the Princess Margaret Cancer Centre international retreat.

  Authors:Roderick Clark, Miran Kenk, Kristen McAlpine, Emily Thain, Kirsten M. Farncombe, Colin C. Pritchard, et al.From:Canadian Urological Association Journal (Vol. 15, Issue 12) Peer-Reviewed

  Dec. 20214,977 words Report 1830LProstate cancer is a significant cause of cancer mortality. It has been well-established that certain germline pathogenic variants confer both an increased risk of being diagnosed with prostate cancer and dying of...

• Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis.

  Authors:Nicolb Pernigoni, Elena Zagato, Martina Troiani, Ricardo Pereira Mestre, Bianca Call, Giuseppe Attanasio, et al.From:Science (Vol. 374, Issue 6564) Peer-Reviewed

  Oct. 8, 20216,700 words Article 1440L

   Abstract Only

• Lutetium-177-PSMA-617 for Metastatic Castration-Resistant Prostate Cancer.

  Authors:Oliver Sartor, Johann de Bono, Kim N. Chi, Karim Fizazi, Ken Herrmann, Kambiz Rahbar, et al.From:The New England Journal of Medicine (Vol. 385, Issue 12) Peer-Reviewed

  Sept. 16, 202126 words Report

   Citation Only

• A streamlined workflow for single-cells genome-wide copy-number profiling by low-pass sequencing of LM-PCR whole-genome amplification products

  Authors:Alberto Ferrarini, Claudio Forcato, Genny Buson, Paola Tononi, Valentina del Monaco, Mario Terracciano, et al.From:PLoS ONE (Vol. 13, Issue 3) Peer-Reviewed

  Mar. 1, 201811,163 words Report 1620LAuthor(s): Alberto Ferrarini 1, Claudio Forcato 1, Genny Buson 1, Paola Tononi 1, Valentina del Monaco 1, Mario Terracciano 1, Chiara Bolognesi 1, Francesca Fontana 1, Gianni Medoro 1, Rui Neves 2, Birte Möhlendick 2,...

• Preclinical evaluation of imaging biomarkers for prostate cancer bone metastasis and response to cabozantinib

  Authors:Timothy J. Graham, Gary Box, Nina Tunariu, Mateus Crespo, Terry J. Spinks, Susana Miranda, et al.From:Journal of the National Cancer Institute (Vol. 106, Issue 4) Peer-Reviewed

  Apr. 9, 2014334 words Author abstract

   Abstract Only

• Interview with Johann de Bono for Future Oncology

  Author:Johann de BonoFrom:Future Oncology (Vol. 8, Issue 11) Peer-Reviewed

  Nov. 20121,025 words Interview 1240LAuthor(s): Johann de Bono 1 What initially drew you towards cancer medicine? Cancer patients themselves initially drew me towards cancer medicine; their courage, determination and their response to suffering, and...

• Prognostic model predicting metastatic castration-resistant prostate cancer survival in men treated with second-line chemotherapy

  Authors:Susan Halabi, Chen-Yen Lin, Eric J. Small, Andrew J. Armstrong, Ellen B. Kaplan, Daniel Petrylak, et al.From:Journal of the National Cancer Institute (Vol. 105, Issue 22) Peer-Reviewed

  Nov. 20, 2013280 words Author abstract, Rep...

   Abstract Only

• A study of PD-L1 expression in KRAS mutant non-small cell lung cancer cell lines exposed to relevant targeted treatments

  Authors:Anna Minchom, Parames Thavasu, Zai Ahmad, Adam Stewart, Alexandros Georgiou, Mary E. R. O'Brien, et al.From:PLoS ONE (Vol. 12, Issue 10) Peer-Reviewed

  Oct. 5, 20173,219 words Report 1580LWe investigated PD-L1 changes in response to MEK and AKT inhibitors in KRAS mutant lung adenocarcinoma (adeno-NSCLC). PD-L1 expression was quantified using immunofluorescence and co-culture with a jurkat cell-line...

• Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer.

  Authors:Ronald de Wit, Johann de Bono, Cora N. Sternberg, Karim Fizazi, Bertrand Tombal, Christian Wulfing, et al.From:The New England Journal of Medicine (Vol. 381, Issue 26) Peer-Reviewed

  Dec. 26, 201951 words Report

   Citation Only

• Hypoxia and Noncoding RNAs in Taxane Resistance

  Authors:Perla Pucci, Pasquale Rescigno, Semini Sumanasuriya, Johann De Bono, and Francesco CreaFrom:Trends in Pharmacological SciencesPeer-Reviewed

  Aug. 2018141 words Report

   Abstract Only

• CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo.

  Authors:Abdullah Alajati, Mariantonietta D'Ambrosio, Martina Troiani, Simone Mosole, Laura Pellegrini, Jingjing Chen, et al.From:Journal of Clinical Investigation (Vol. 130, Issue 5) Peer-Reviewed

  May 202010,623 words Article 1410LThe mechanisms by which prostate cancer shifts from an indolent castration-sensitive phenotype to lethal castration-resistant prostate cancer (CRPC) are poorly understood. Identification of clinically relevant genetic...

• Olaparib for Metastatic Castration-Resistant Prostate Cancer.

  Authors:Johann De Bono, Joaquin Mateo, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, et al.From:The New England Journal of Medicine (Vol. 382, Issue 22) Peer-Reviewed

  May 28, 202050 words Report

   Citation Only

• Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial

  Authors:Nicholas D James, Matthew R Sydes, Noel W Clarke, Malcolm D Mason, David P Dearnaley, Melissa R Spears, et al.From:The Lancet (Vol. 387, Issue 10024) Peer-Reviewed

  Mar. 19, 20161,196 words Article

   Abstract Only

• The landscape of RNA polymerase II-associated chromatin interactions in prostate cancer.

  Authors:Susmita G. Ramanand, Yong Chen, Jiapei Yuan, Kelly Daescu, Maryou B.K. Lambros, Kathleen E. Houlahan, et al.From:Journal of Clinical Investigation (Vol. 130, Issue 8) Peer-Reviewed

  Aug. 202011,686 words Article 1430LTranscriptional dysregulation is a hallmark of prostate cancer (PCa). We mapped the RNA polymerase II-associated (RNA Pol II-associated) chromatin interactions in normal prostate cells and PCa cells. We discovered...

• A study of motivations and expectations of patients seen in phase 1 oncology clinics

  Authors:Saoirse O. Dolly, Eleftheria Kalaitzaki, Martina Puglisi, Sarah Stimpson, Janet Hanwell, Sonia Serrano Fandos, et al.From:Cancer (Vol. 122, Issue 22) Peer-Reviewed

  Nov. 15, 2016 Report

   Citation Only

• Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer.

  Authors:Maha Hussain, Joaquin Mateo, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, et al.From:The New England Journal of Medicine (Vol. 383, Issue 24) Peer-Reviewed

  Dec. 10, 202052 words Report

   Citation Only

• Differential impact of RB status on E2F1 reprogramming in human cancer

  Authors:Christopher McNair, Kexin Xu, Amy C. Mandigo, Matteo Benelli, Benjamin Leiby, Daniel Rodrigues, et al.From:Journal of Clinical Investigation (Vol. 128, Issue 1) Peer-Reviewed

  Jan. 201811,614 words Article 1670LThe tumor suppressor protein retinoblastoma (RB) is mechanistically linked to suppression of transcription factor E2F1 -mediated cell cycle regulation. For multiple tumor types, loss of RB function is associated with...

• Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer

  Authors:Adam Sharp, Ilsa Coleman, Wei Yuan, Cynthia Sprenger, David Dolling, Daniel Nava Rodrigues, et al.From:Journal of Clinical Investigation (Vol. 129, Issue 1) Peer-Reviewed

  Jan. 201912,007 words Report 1410LBACKGROUND. Liquid biopsies have demonstrated that the constitutively active androgen receptor splice variant-7 (AR-V7) associates with reduced response and overall survival from endocrine therapies in...

• Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

  Authors:Peter C. Fong, David S. Boss, Timothy A. Yap, Andrew Tutt, Peijun Wu, Marja Mergui-Roelvink, et al.From:The New England Journal of Medicine (Vol. 361, Issue 2) Peer-Reviewed

  July 9, 200946 words Clinical report

   Citation Only

• Integrative Clinical Genomics of Advanced Prostate Cancer

  Authors:Dan Robinson, Eliezer M. Van Allen, Yi-Mi Wu, Nikolaus Schultz, Robert J. Lonigro, Juan-Miguel Mosquera, et al.From:Cell (Vol. 161, Issue 5) Peer-Reviewed

  May 21, 20151,161 words Article

   Abstract Only