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    Academic Journals

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• Bi-Directional Exchange of Membrane Components Occurs during Co-Culture of Mesenchymal Stem Cells and Nucleus Pulposus Cells

  Authors:Sandra Strassburg, Nigel W. Hodson, Patrick I. Hill, Stephen M. Richardson, and Judith A. HoylandFrom:PLoS ONE (Vol. 7, Issue 3) Peer-Reviewed

  Mar. 15, 20125,539 words Article 1560LAuthor(s): Sandra Strassburg 1 , Nigel W. Hodson 1 , Patrick I. Hill 2 , Stephen M. Richardson 1 , Judith A. Hoyland 1 , * Introduction A change in cellular phenotype of the nucleus pulposus (NP) cells residing in...

• Human decellularized bone scaffolds from aged donors show improved osteoinductive capacity compared to young donor bone

  Authors:Christopher A. Smith, Tim N. Board, Paul Rooney, Mark J. Eagle, Stephen M. Richardson, and Judith A. HoylandFrom:PLoS ONE (Vol. 12, Issue 5) Peer-Reviewed

  May 15, 20176,227 words Report 1720LTo improve the safe use of allograft bone, decellularization techniques may be utilized to produce acellular scaffolds. Such scaffolds should retain their innate biological and biomechanical capacity and support...

• Integrin - Dependent Mechanotransduction in Mechanically Stimulated Human Annulus Fibrosus Cells: Evidence for an Alternative Mechanotransduction Pathway Operating with Degeneration

  Authors:Hamish T. J. Gilbert, Navraj S. Nagra, Anthony J. Freemont, Sarah J. Millward-Sadler, and Judith A. HoylandFrom:PLoS ONE (Vol. 8, Issue 9) Peer-Reviewed

  Sept. 5, 20136,902 words Article 1760LIntervertebral disc (IVD) cells derived from degenerate tissue respond aberrantly to mechanical stimuli, potentially due to altered mechanotransduction pathways. Elucidation of the altered, or alternative,...

• Understanding the native nucleus pulposus cell phenotype has important implications for intervertebral disc regeneration strategies

  Authors:Francesca E Ludwinski, Kanna Gnanalingham, Stephen M Richardson, and Judith A HoylandFrom:Regenerative Medicine (Vol. 8, Issue 1)

  Jan. 20139,757 words Report 1660LAuthor(s): Francesca E Ludwinski 1 , Kanna Gnanalingham 2 , Stephen M Richardson 1 , Judith A Hoyland [*] 3 KEYWORDS : degeneration; intervertebral disc; low back pain; notochord; nucleus pulposus; phenotype;...

• Novel Immortal Cell Lines Support Cellular Heterogeneity in the Human Annulus Fibrosus

  Authors:Guus G. H. van den Akker, Don A. M. Surtel, Andy Cremers, Stephen M. Richardson, Judith A. Hoyland, Lodewijk W. van Rhijn, et al.From:PLoS ONE (Vol. 11, Issue 1) Peer-Reviewed

  Jan. 21, 20168,786 words Report 1380LIntroduction Loss of annulus fibrosus (AF) integrity predisposes to disc herniation and is associated with IVD degeneration. Successful implementation of biomedical intervention therapy requires in-depth knowledge of...

• Correction: Human decellularized bone scaffolds from aged donors show improved osteoinductive capacity compared to young donor bone

  Authors:Christopher A. Smith, Tim N. Board, Paul Rooney, Mark J. Eagle, Stephen M. Richardson, and Judith A. HoylandFrom:PLoS ONE (Vol. 12, Issue 11) Peer-Reviewed

  Nov. 2, 2017129 words Brief article, Corre... 1090LAuthor(s): Christopher A. Smith, Tim N. Board, Paul Rooney, Mark J. Eagle, Stephen M. Richardson, Judith A. Hoyland In the Funding section, the grant numbers are missing. The grant number for the John Charnley Trust...

• Simultaneous orthogonal dual-click approach to tough, in-situ-forming hydrogels for cell encapsulation

  Authors:Vinh X. Truong, Matthew P. Ablett, Stephen M. Richardson, Judith A. Hoyland, and Andrew P. DoveFrom:Journal of the American Chemical Society (Vol. 137, Issue 4) Peer-Reviewed

  Feb. 4, 201568 words Report

   Abstract Only

• Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype

  Authors:Sandra Strassburg, Stephen M Richardson, Anthony J Freemont, and Judith A HoylandFrom:Regenerative Medicine (Vol. 5, Issue 5)

  Sept. 20106,109 words Report Author(s): Sandra Strassburg 1 , Stephen M Richardson 1 , Anthony J Freemont 1 , Judith A Hoyland [[dagger]] 2 KEYWORDS: co-culture; intervertebral disc regeneration; mesenchymal stem cells; nucleus pulposus...

• Degenerate Human Nucleus Pulposus Cells Promote Neurite Outgrowth in Neural Cells

  Authors:Stephen M. Richardson, Devina Purmessur, Pauline Baird, Ben Probyn, Anthony J. Freemont, and Judith A. HoylandFrom:PLoS ONE (Vol. 7, Issue 10) Peer-Reviewed

  Oct. 16, 20124,574 words Report 1640LAuthor(s): Stephen M. Richardson, Devina Purmessur, Pauline Baird, Ben Probyn, Anthony J. Freemont, Judith A. Hoyland * Introduction Low back pain (LBP) is a widespread and debilitating disorder which causes a...

• Human Adipose-Derived Stem Cells Exhibit Enhanced Proliferative Capacity and Retain Multipotency Longer than Donor-Matched Bone Marrow Mesenchymal Stem Cells during Expansion In Vitro

  Authors:Kimberley L. Burrow, Judith A. Hoyland, and Stephen M. RichardsonFrom:Stem Cells International (Vol. 2017) Peer-Reviewed

  Annual 20178,143 words Report 1600LBone marrow-derived mesenchymal stem cells (MSCs) and adipose-derived multipotent/mesenchymal stem cells (ASCs) have been proposed as the ideal cell types for a range of musculoskeletal tissue engineering and...