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    Academic Journals

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• Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1 and 3 in Gastric and Esophageal Adenocarcinoma

  Authors:Charlotta Hedner, David Borg, Bjorn Nodin, Emelie Karnevi, Karin Jirstrom, and Jakob EberhardFrom:PLoS ONE (Vol. 11, Issue 2) Peer-Reviewed

  Feb. 4, 20167,456 words Report 1540LBackground Gastric and esophageal adenocarcinomas are major global cancer burdens. These cancer forms are characterized by a poor prognosis and a modest response to chemo- radio- and targeted treatment. Hence there...

• Increased androgen receptor expression in serous carcinoma of the ovary is associated with an improved survival

  Authors:Bjorn Nodin, Nooreldin Zendehrokh, Jenny Brandstedt, Elise Nilsson, Jonas Manjer, Donal J. Brennan, et al.From:Journal of Ovarian Research (Vol. 3) Peer-Reviewed

  June 17, 20102,797 words Report Background Altered androgen hormone homeostasis and androgen receptor (AR) activity have been implicated in ovarian carcinogenesis but the relationship between AR expression in ovarian cancer and clinical outcome...

• Associations of Anthropometric Factors with KRAS and BRAF Mutation Status of Primary Colorectal Cancer in Men and Women: A Cohort Study

  Authors:Jenny Brandstedt, Sakarias Wangefjord, Bjorn Nodin, Jakob Eberhard, Magnus Sundstrom, Jonas Manjer, et al.From:PLoS ONE (Vol. 9, Issue 6) Peer-Reviewed

  June 11, 20145,923 words Clinical report 1600LObesity is a well-established risk factor for colorectal cancer (CRC), and accumulating evidence suggests a differential influence of sex and anthropometric factors on the molecular carcinogenesis of the disease. The...

• Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients

  Authors:Caroline Holm, Suresh Rayala, Karin Jirstrom, Olle Stal, Rakesh Kumar, and Goran LandbergFrom:Journal of the National Cancer Institute (Vol. 98, Issue 10) Peer-Reviewed

  May 17, 2006325 words Author abstract, Cli... 60L

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• Expression of the global regulator SATB1 is an independent factor of poor prognosis in high grade epithelial ovarian cancer

  Authors:Bjorn Nodin, Charlotta Hedner, Mathias Uhlnn, and Karin JirstromFrom:Journal of Ovarian Research (Vol. 5, Issue 1) Peer-Reviewed

  Sept. 19, 20122,901 words Report 1630LBackground The global gene regulator Special AT-rich sequence-binding protein1 (SATB1) has been reported to reprogramme tumour cells into a more malignant phenotype and associate with poor clinical outcome in several...

• A comparison of tumor biology in primary ductal carcinoma in situ recurring as invasive carcinoma versus a new in Situ

  Authors:Wenjing Zhou, Christine Johansson, Karin Jirstrom, Anita Ringberg, Carl Blomqvist, Rose-Marie Amini, et al.From:International Journal of Breast CancerPeer-Reviewed

  Annual 20144,383 words Report 1360LIntroduction. About half of all new ipsilateral events after a primary ductal carcinoma in situ (DCIS) are invasive carcinoma. We studied tumor markers in the primary DCIS in relation to type of event (invasive versus...

• Immune effector monocyte-neutrophil cooperation induced by the primary tumor prevents metastatic progression of breast cancer.

  Authors:Catharina Hagerling, Hugo Gonzalez, Kiarash Salari, Chin-Yang Wang, Charlene Lin, Isabella Robles, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 116, Issue 43) Peer-Reviewed

  Oct. 22, 20197,597 words Article 1510L

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• Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1, 2 and 3 in Periampullary Adenocarcinoma

  Authors:Jacob Elebro, Margareta Heby, Carl Fredrik Warfvinge, Bjorn Nodin, Jakob Eberhard, and Karin JirstromFrom:PLoS ONE (Vol. 11, Issue 4) Peer-Reviewed

  Apr. 12, 20166,647 words Report 1620LPeriampullary adenocarcinoma, including pancreatic cancer, is a heterogeneous group of tumours with dismal prognosis, for which there is an urgent need to identify novel treatment strategies. The human epithelial growth...

• Downregulation of miR-92a Is Associated with Aggressive Breast Cancer Features and Increased Tumour Macrophage Infiltration

  Authors:Sofie Nilsson, Christina Moller, Karin Jirstrom, Alexander Lee, Susann Busch, Rebecca Lamb, et al.From:PLoS ONE (Vol. 7, Issue 4) Peer-Reviewed

  Apr. 26, 20125,023 words Article 1560LBackground MicroRNAs are small non-coding RNAs involved in the regulation of gene expression on a posttranscriptional level. These regulatory RNAs have been implicated in numerous cellular processes and are further...

• Diagnostic Value of Insulinoma-Associated Protein 1 (INSM1) and Comparison With Established Neuroendocrine Markers in Pulmonary Cancers: A Comprehensive Study and Review of the Literature.

  Authors:Johan Staaf, Lena Tran, Linnea Soderlund, Bjorn Nodin, Karin Jirstrom, Haifa Vidarsdottir, et al.From:Archives of Pathology & Laboratory Medicine (Vol. 144, Issue 9) Peer-Reviewed

  Sept. 20206,825 words Article 1860LContext.--The diagnostic distinction of pulmonary neuroendocrine (NE) tumors from non-small cell lung carcinomas (NSCLCs) is clinically relevant for prognostication and treatment. Diagnosis is based on morphology and...

• Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice

  Authors:Moshe Elkabets, Ann M. Gifford, Christina Scheel, Bjorn Nilsson, Ferenc Reinhardt, Mark-Anthony Bray, et al.From:Journal of Clinical Investigation (Vol. 121, Issue 2) Peer-Reviewed

  Feb. 201110,333 words Clinical report 1460LSystemic instigation is a process by which endocrine signals sent from certain tumors (instigators) stimulate BM cells (BMCs), which are mobilized into the circulation and subsequently foster the growth of otherwise...

• Plasma folate concentrations are positively associated with risk of estrogen receptor [beta] negative breast cancer in a Swedish nested case control study

  Authors:Ulrika Ericson, Signe Borgquist, Malin I.L. Ivarsson, Emily Sonestedt, Bo Gullberg, Joyce Carlson, et al.From:The Journal of Nutrition (Vol. 140, Issue 9) Peer-Reviewed

  Sept. 2010248 words Author abstract, Cli...

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• Low body mass index but high fat and energy intake are associated with the emergence of a less malignant phenotype of breast cancer defined by tumor grade, proliferation, and sets of cell cycle regulators

  Authors:Signe Borgquist, Elisabet Wirfalt, Karin Jirstrom, Lola Anagnostaki, Bo Gullberg, Goran Berglund, et al.From:The Journal of Nutrition (Vol. 135, Issue 12) Peer-Reviewed

  Dec. 2005252 words Author abstract

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• Expression and prognostic significance of the polymeric immunoglobulin receptor in epithelial ovarian cancer

  Authors:Jonna Berntsson, Sebastian Lundgren, Bjorn Nodin, Mathias Uhlnn, Alexander Gaber, and Karin JirstromFrom:Journal of Ovarian Research (Vol. 7, Issue 1) Peer-Reviewed

  Feb. 26, 20144,892 words Article 1470LBackground High expression of the polymeric immunoglobulin receptor (PIGR) has previously been associated with a favourable prognosis in a few cancer forms, but its expression and relationship with clinical outcome...

• Low RBM3 Protein Expression Correlates with Clinical Stage, Prognostic Classification and Increased Risk of Treatment Failure in Testicular Non-Seminomatous Germ Cell Cancer

  Authors:Sven-Erik Olofsson, Bjorn Nodin, Alexander Gaber, Jakob Eberhard, Mathias Uhlen, Karin Jirstrom, et al.From:PLoS ONE (Vol. 10, Issue 3) Peer-Reviewed

  Mar. 26, 20154,467 words Article 1520LBackground Expression of the RNA-binding motif protein 3 (RBM3) has been shown to correlate with favourable clinicopathological parameters and prognosis in several cancer diseases. The aim of this study was to...

• High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer

  Authors:Christina Siesing, Halfdan Sorbye, Anca Dragomir, Per Pfeiffer, Camilla Qvortrup, Fredrik Ponten, et al.From:PLoS ONE (Vol. 12, Issue 8) Peer-Reviewed

  Aug. 11, 20174,914 words Article 1480LBackground High expression of the RNA-binding motif protein 3 (RBM3) has been shown to correlate, with prolonged survival in several malignant diseases and with the benefit of platinum-based chemotherapy in ovarian...

• Translational Database Selection and Multiplexed Sequence Capture for Up Front Filtering of Reliable Breast Cancer Biomarker Candidates

  Authors:Patrik L. Stahl, Magnus K. Bjursell, Hovsep Mahdessian, Sophia Hober, Karin Jirstrom, and Joakim LundebergFrom:PLoS ONE (Vol. 6, Issue 6) Peer-Reviewed

  June 15, 20113,542 words Article 1640LBiomarker identification is of utmost importance for the development of novel diagnostics and therapeutics. Here we make use of a translational database selection strategy, utilizing data from the Human Protein Atlas...

• Discovery of dachshund 2 protein as a novel biomarker of poor prognosis in epithelial ovarian cancer

  Authors:Bjorn Nodin, Marie Fridberg, Mathias Uhlen, and Karin JirstromFrom:Journal of Ovarian Research (Vol. 5) Peer-Reviewed

  Jan. 27, 20124,868 words Clinical report 1600LBackground The Dachshund homolog 2 (DACH2) gene has been implicated in development of the female genital tract in mouse models and premature ovarian failure syndrome, but to date, its expression in human normal and...

• Ovarian cancer subtypes and survival in relation to three comprehensive imaging parameters

  Authors:Hanna Sartor, Maria Bjurberg, Mihaela Asp, Anna Kahn, Jenny Brandstedt, Paivi Kannisto, et al.From:Journal of Ovarian Research (Vol. 13, Issue 1) Peer-Reviewed

  Mar. 7, 20203,946 words Clinical report 1540LBackground Ovarian cancer (OC) is usually detected in late clinical stages, and imaging at diagnosis is crucial. Peritoneal carcinomatosis (PC) and cardio phrenic lymph nodes (CPLN) are pathological findings of...

• Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer

  Authors:Gillian O'Hurley, Christer Busch, Linn Fagerberg, Bjorn M. Hallstrom, Charlotte Stadler, Anna Tolf, et al.From:PLoS ONE (Vol. 10, Issue 8) Peer-Reviewed

  Aug. 3, 20157,042 words Report 1650LTo better understand prostate function and disease, it is important to define and explore the molecular constituents that signify the prostate gland. The aim of this study was to define the prostate specific...