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From:Nature Medicine (Vol. 22, Issue 2) Peer-ReviewedRecent genomic studies have resulted in an emerging understanding of the role of chromatin regulators in the development of cancer. EZH2, a histone methyl transferase subunit of a Polycomb repressor complex, is...
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From:Nature Medicine (Vol. 21, Issue 12) Peer-ReviewedThe authors identify EZH2 as a general underlying dependency of tumors with mutations in the SWI/SNF chromatin regulator complex, and they show that EZH2's pro-tumorigenic role may be dependent on non-catalytic...
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From:Nature Medicine (Vol. 21, Issue 12) Peer-ReviewedHuman cancer genome sequencing has recently revealed that genes that encode subunits of SWI/SNF chromatin remodeling complexes are frequently mutated across a wide variety of cancers, and several subunits of the complex...
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From:Journal of Cultural Diversity (Vol. 10, Issue 4) Peer-ReviewedEdited by Dana Beth Weinberg (2003) Forwarded by Suzanne Gordon (ISBN 0-8014-3980-9, 213 pages, $25 hardcover) Code Green: Money Driven Hospitals and The Dismantling of Nursing is a scholarly work that examines the...