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From:PLoS ONE (Vol. 16, Issue 2) Peer-ReviewedDuchenne muscular dystrophy is initiated by dystrophin deficiency, but downstream pathophysiological pathways such as membrane instability, NFÄ¸B activation, mitochondrial dysfunction, and induction of TGF[beta] fibrosis...
From:PLoS ONE (Vol. 8, Issue 6) Peer-ReviewedIntroduction Congenital muscular dystrophy is a distinct group of diseases presenting with weakness in infancy or childhood and no current therapy. One form, MDC1A, is the result of laminin alpha-2 deficiency and...
From:PLoS ONE (Vol. 8, Issue 5) Peer-ReviewedAsthma is a chronic inflammatory condition of the lower respiratory tract associated with airway hyperreactivity and mucus obstruction in which a majority of cases are due to an allergic response to environmental...
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