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• A Method for Efficient Calculation of Diffusion and Reactions of Lipophilic Compounds in Complex Cell Geometry

  Authors:Kristian Dreij, Qasim Ali Chaudhry, Bengt Jernstrom, Ralf Morgenstern, and Michael HankeFrom:PLoS ONE (Vol. 6, Issue 8) Peer-Reviewed

  Aug. 31, 201111,584 words Article 1460LA general description of effects of toxic compounds in mammalian cells is facing several problems. Firstly, most toxic compounds are hydrophobic and partition phenomena strongly influence their behaviour. Secondly,...

• [O.sup.6]-methylguanine--induced transcriptional mutagenesis reduces p53 tumor-suppressor function

  Authors:Monika Ezerskyte, Joao A. Paredes, Stefano Malvezzi, John A. Burns, Geoffrey P. Margison, Magnus Olsson, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 115, Issue 18) Peer-Reviewed

  May 1, 20186,181 words Report 1460L

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• Exocrine Pancreatic Carcinogenesis and Autotaxin Expression

  Authors:Sandeep Kadekar, Ilona Silins, Anna Korhonen, Kristian Dreij, Lauy Al-Anati, Johan Hogberg, et al.From:PLoS ONE (Vol. 7, Issue 8) Peer-Reviewed

  Aug. 29, 20128,383 words Report 1380LAuthor(s): Sandeep Kadekar 1 , Ilona Silins 1 , * , Anna Korhonen 2 , Kristian Dreij 1 , Lauy Al-Anati 1 , Johan Högberg 1 , Ulla Stenius 1 Introduction Exocrine pancreatic cancer is the fifth major cause of...

• Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1

  Authors:Lars Brautigam, Lasse Dahl Ejby Jensen, Gereon Poschmann, Staffan Nystrom, Sarah Bannenberg, Kristian Dreij, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 110, Issue 50) Peer-Reviewed

  Dec. 10, 2013189 words Author abstract, Rep...

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• Application of Text Mining in Risk Assessment of Chemical Mixtures: A Case Study of Polycyclic Aromatic Hydrocarbons (PAHs).

  Authors:Imran Ali, Kristian Dreij, Simon Baker, Johan Hogberg, Anna Korhonen, and Ulla SteniusFrom:Environmental Health Perspectives (Vol. 129, Issue 6) Peer-Reviewed

  June 20218,882 words Case study 1540LBackground: Cancer risk assessment of complex exposures, such as exposure to mixtures of polycyclic aromatic hydrocarbons (PAHs), is challenging due to the diverse biological activities of these compounds. With the help...