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Academic Journals
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From:BioMed Research International (Vol. 2022) Peer-ReviewedDue to the high homology of the ATP sites of the JAK family, the development of selective inhibitors for a certain JAK isoform is extremely challenging. Our strategy to achieve high selectivity for TYK2 relies on...
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From:PLoS ONE (Vol. 17, Issue 4) Peer-ReviewedMammary gland is present in all mammals and usually functions in producing milk to feed the young offspring. Mammogenesis refers to the growth and development of mammary gland, which begins at puberty and ends after...
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From:BioMed Research International (Vol. 2022) Peer-ReviewedCOVID-19 is hypothesized to be linked to the host's excessive inflammatory immunological response to SARS-CoV-2 infection, which is regarded to be a major factor in disease severity and mortality. Numerous immune cells...
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From:Atmospheric Chemistry and Physics (Vol. 22, Issue 7) Peer-ReviewedA large population in China has been exposed to both severe ozone (O.sub.3) pollution and extreme heat under global warming. Here, the spatiotemporal characteristics of coupled extremes in surface O.sub.3 and heat (OPCs)...
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From:Journal of Oncology (Vol. 2022) Peer-ReviewedAcute lymphoblastic leukemia (ALL) is the most serious hematological carcinoma in adolescents. The significance of long noncoding RNAs (lncRNAs) and their regulative role in the proliferation and differentiation of...
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From:Atmospheric Chemistry and Physics (Vol. 22, Issue 6) Peer-ReviewedWe examined the impacts of aerosol-radiation interactions, including the effects of aerosol-photolysis interaction (API) and aerosol-radiation feedback (ARF), on surface-layer ozone (O.sub.3) concentrations during four...
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From:Journal of Oncology (Vol. 2022) Peer-ReviewedBackground. The treatment of hepatocellular carcinoma (HCC) patients with portal vein tumor thrombus (PVTT) remains controversial due to the limited effect of sorafenib. The aim of the study was to investigate whether...
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From:Journal of Oncology (Vol. 2022) Peer-ReviewedPurpose. To quantify the long-term evaluation of optic chiasma (OC) and/or optic nerve(s) (ONs) and to develop predictive models for radiation-induced optic neuropathy (RION) in nasopharyngeal carcinoma after...
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From:Atmospheric Chemistry and Physics (Vol. 22, Issue 3) Peer-ReviewedVertical profiles of black carbon (BC) play a critical role in modifying the meteorological conditions such as temperature, planetary boundary layer height (PBLH), and regional circulation, which influence surface layer...
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From:Frontiers of Physics (Vol. 17, Issue 1) Peer-ReviewedIn this paper, we propose a scheme to achieve a multiphonon-resonance quantum Rabi model and adiabatic passage in a strong-coupling cavity optomechanical system. In the scheme, when the driving bichromatic laser beam is...
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From:Annals of Operations Research (Vol. 309, Issue 2) Peer-ReviewedIn cross-border logistics, mainline carriers (MCs) confronting demand uncertainty have to share their information with the overseas regional carrier (RC) via information system or electronic data interchange. However,...
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From:Journal of Experimental & Clinical Cancer Research (Vol. 41, Issue 1) Peer-ReviewedAuthor(s): Hao Peng1, Jian Zhang2, Pan-Pan Zhang2, Lei Chen1, Ling-Long Tang1, Xiao-Jing Yang2, Qing-Mei He2, Xin Wen2, Ying Sun1, Na Liu2, Ying-Qin Li2 and Jun Ma1 Correction to: J Exp Clin Cancer Res 38, 11 (2019)...
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From:BioMed Research International (Vol. 2022) Peer-ReviewedMethylation is one of the most common and considerable modifications in biological systems mediated by multiple enzymes. Recent studies have shown that methylation has been widely identified in different RNA molecules....