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    Academic Journals

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• Whole genome sequence and comparative analysis of Borrelia burgdorferi MM1

  Authors:Neda Jabbari, Gustavo Glusman, Lena M. Joesch-Cohen, Panga Jaipal Reddy, Robert L. Moritz, Leroy Hood, et al.From:PLoS ONE (Vol. 13, Issue 6) Peer-Reviewed

  June 11, 20186,844 words Report 1540LLyme disease is caused by spirochaetes of the Borrelia burgdorferi sensu lato genospecies. Complete genome assemblies are available for fewer than ten strains of Borrelia burgdorferi sensu stricto, the primary cause of...

• From hematopoiesis to neuropoiesis: Evidence of overlapping genetic programs

  Authors:Alexey V. Terskikh, Mathew C. Easterday, Linheng Li, Leroy Hood, Harley I. Kornblum, Daniel H. Geschwind, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 98, Issue 14) Peer-Reviewed

  July 3, 2001178 words Article

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• Biotechnology and medicine of the future

  Author:Leroy HoodFrom:JAMA, The Journal of the American Medical Association (Vol. 259, Issue 12) Peer-Reviewed

  Mar. 25, 1988112 words Article

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• Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

  Authors:Jinko Graham, William A. Hagopian, Ingrid Kockum, Lou Sheng Li, Carani B. Sanjeevi, Robert M. Lowe, et al.From:Diabetes (Vol. 51, Issue 5) Peer-Reviewed

  May 20028,645 words Article Age-dependent associations between type 1 diabetes risk genes HLA, INS VNTR, and CTLA-4 and autoantibodies to GAD65 (GADAs), ICA512/IA-2, insulin, and islet cells were determined by logistic regression analysis in 971...

• Rapid screening of peptide probes through in situ single-bead sequencing microarray

  Authors:Weizhi Wang, Zewen Wei, Di Zhang, Huailei Ma, Zihua Wang, Xiangli Bu, et al.From:Analytical Chemistry (Vol. 86, Issue 23) Peer-Reviewed

  Dec. 2, 201480 words Report

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• Localization of diphtheria toxin nuclease activity to fragment A

  Authors:Stephen L. Lessnick, Jeffrey B. Lyczak, Can Bruce, Donald G. Lewis, Phillip S. Kim, Mark L. Stolowitz, et al.From:Journal of Bacteriology (Vol. 174, Issue 5-6) Peer-Reviewed

  Mar. 199270 words Article

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• Glossary of genetic terms

  Authors:Daniel J. Kevles and Leroy HoodFrom:National Forum (Vol. 73, Issue 2)

  Spring 1993978 words Glossary A collection of scientific terms relating to genetics is presented. Included are brief descriptions of these technical terms which are most often used by those engaged in the fields of genetic research. allele--One of...

• Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structure

  Authors:Motoshi Suzuki, Dale Baskin, Leroy Hood, and Lawrence A. LoebFrom:Proceedings of the National Academy of Sciences of the United States (Vol. 93, Issue 18) Peer-Reviewed

  Sept. 3, 1996230 words Article

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• Systems biology and new technologies enable predictive and preventative medicine

  Authors:Leroy Hood, James R. Heath, Michael E. Phelps, and Biaoyang LinFrom:Science (Vol. 306, Issue 5696) Peer-Reviewed

  Oct. 22, 20043,096 words Article 1580LSystems approaches to disease are grounded in the idea that disease-perturbed protein and gene regulatory networks differ from their normal counterparts; we have been pursuing the possibility that these differences may...

• Chromosomal haplotypes by genetic phasing of human families

  Authors:Jared C. Roach, Gustavo Glusman, Robert Hubley, Stephen Z. Montsaroff, Alisha K. Holloway, Denise E. Mauldin, et al.From:American Journal of Human Genetics (Vol. 89, Issue 3) Peer-Reviewed

  Sept. 9, 201172 words Report

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• Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes. (Research Article)

  Authors:Samuel Aparicio, Jarrod Chapman, Elia Stupka, Nik Putnam, Jer-ming Chia, Paramvir Dehal, et al.From:Science (Vol. 297, Issue 5585) Peer-Reviewed

  Aug. 23, 20027,022 words Article The compact genome of Fugu rubripes has been sequenced to over 95% coverage, and more than 80% of the assembly is in multigene-sized scaffolds. In this 365-megabase vertebrate genome, repetitive DNA accounts for less...

• Direct multiplexed measurement of gene expression with color-coded probe pairs

  Authors:Gary K. Geiss, Roger E. Bumgarner, Brian Birditt, Timothy Dahl, Naeem Dowidar, Dwayne L. Dunaway, et al.From:Nature Biotechnology (Vol. 26, Issue 3) Peer-Reviewed

  Mar. 20087,916 words Article 1400LWe describe a technology, the NanoString nCounter gene expression system, which captures and counts individual mRNA transcripts. Advantages over existing platforms include direct measurement of mRNA expression levels...

• Identification of T-cell receptor alpha-chain genes in the chicken

  Authors:Thomas W. Gobel, Chen-Lo H. Chen, Jill Lahti, Takayuki Kubota, Chai-Lam Kuo, Ruedi Aebersold, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 91, Issue 3) Peer-Reviewed

  Feb. 1, 199447 words Article

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• Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.

  Authors:Yapeng Su, Daniel Chen, Dan Yuan, Christopher Lausted, Jongchan Choi, Chengzhen L. Dai, et al.From:Cell (Vol. 183, Issue 6) Peer-Reviewed

  Dec. 10, 2020713 words Article

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• Transgenic mouse model for neurocristopathy: Schwannomas and facial bone tumors

  Authors:Niels A. Jensen, Michael L. Rodriguez, Justine S. Garvey, Carol A. Miller, and Leroy HoodFrom:Proceedings of the National Academy of Sciences of the United States (Vol. 90, Issue 8) Peer-Reviewed

  Apr. 15, 199366 words Article

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• Isolation of unknown genes from human bone marrow by differential screening and single-pass cDNA sequence determination

  Authors:Sally L. Orr, Tim P. Hughes, Charles L. Sawyers, Roberta M. Kato, Shirley G. Quan, Suzanne P. Williams, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 91, Issue 25) Peer-Reviewed

  Dec. 6, 199484 words Article

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• Corrigendum: Direct multiplexed measurement of gene expression with color-coded probe pairs

  Authors:Gary K. Geiss, Roger E. Bumgarner, Brian Birditt, Timothy Dahl, Naeem Dowidar, Dwayne L. Dunaway, et al.From:Nature Biotechnology (Vol. 26, Issue 6) Peer-Reviewed

  June 2008236 words Brief article, Corre... In the version of this article initially published, the list of authors omitted the final author, Krassen Dimitrov, and should have read as follows: Gary K Geiss (1), Roger E Bumgarner (2), Brian Birditt (1), Timothy...

• Optimal Scaling of Digital Transcriptomes

  Authors:Gustavo Glusman, Juan Caballero, Max Robinson, Burak Kutlu, and Leroy HoodFrom:PLoS ONE (Vol. 8, Issue 11) Peer-Reviewed

  Nov. 6, 201310,622 words Article 1460LDeep sequencing of transcriptomes has become an indispensable tool for biology, enabling expression levels for thousands of genes to be compared across multiple samples. Since transcript counts scale with sequencing...

• A physical map of the human genome

  Authors:John D. McPherson, Marco Marra, LaDeana Hillier, Robert H. Waterston, Asif Chinwalla, John Wallis, et al.From:Nature (Vol. 409, Issue 6822) Peer-Reviewed

  Feb. 15, 20017,704 words Article 1510LThe human genome is by far the largest genome to be sequenced, and its size and complexity present many challenges for sequence assembly. The International Human Genome Sequencing Consortium constructed a map of the...

• Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas

  Authors:Nathan D. Price, Jonathan Trent, Adel K. El- Naggar, David Cogdell, Ellen Taylor, Kelly K. Hunt, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 104, Issue 9) Peer-Reviewed

  Feb. 27, 2007238 words Author abstract 60L

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