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    Academic Journals

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• Circulating MicroRNAs, Polychlorinated Biphenyls, and Environmental Liver Disease in the Anniston Community Health Survey.

  Authors:Matthew C. Cave, Christina M. Pinkston, Shesh N. Rai, Banrida Wahlang, Marian Pavuk, Kimberly Z. Head, et al.From:Environmental Health Perspectives (Vol. 130, Issue 1) Peer-Reviewed

  Jan. 20228,633 words Report 1390LBackground: Polychlorinated biphenyl (PCB) exposures have been associated with liver injury in human cohorts, and steatohepatitis with liver necrosis in model systems. MicroRNAs (miRs) maintain cellular homeostasis and...

• Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers.

  Authors:Heather B. Patisaul, Mamta Behl, Linda S. Birnbaum, Arlene Blum, Miriam L. Diamond, Seth Rojello Fernandez, et al.From:Environmental Health Perspectives (Vol. 129, Issue 10) Peer-Reviewed

  Oct. 202110,618 words Report 1500LBackground: To date, the toxicity of organophosphate esters has primarily been studied regarding their use as pesticides and their effects on the neurotransmitter acetylcholinesterase (AChE). Currently, flame retardants...

• Polybrominated diphenyl ethers: a case study for using biomonitoring data to address risk assessment questions

  Authors:Linda S. Birnbaum and Elaine A. Cohen HubalFrom:Environmental Health Perspectives (Vol. 114, Issue 11) Peer-Reviewed

  Nov. 20066,868 words Article 1330LThe use of biomonitoring data holds promise for characterizing exposure and informing risk assessment. Biomonitoring data have been used successfully to track population trends, identify susceptible populations, and...

• Genetic modification of the association between peripubertal dioxin exposure and pubertal onset in a cohort of Russian boys

  Authors:Olivier Humblet, Susan A. Korrick, Paige L. Williams, Oleg Sergeyev, Claude Emond, Linda S. Birnbaum, et al.From:Environmental Health Perspectives (Vol. 121, Issue 1) Peer-Reviewed

  Jan. 20136,065 words Report 1420LBACKGROUND: Exposure to dioxins has been associated with delayed pubertal onset in both epidemiologic and animal studies. Whether genetic polymorphisms may modify this association is currently unknown. Identifying such...

• Environmental chemicals: evaluating low-dose effects

  Author:Linda S. BirnbaumFrom:Environmental Health Perspectives (Vol. 120, Issue 4) Peer-Reviewed

  Apr. 20121,345 words Editorial 1670LAround the world, large-scale biomonitoring programs have provided extensive information about human exposure to a large number of environmental chemicals (Barr et al. 2010; Bilau et al. 2008; Churchill et al. 2001;...

• Applying Research to public health questions: biologically relevant exposures

  Author:Linda S. BirnbaumFrom:Environmental Health Perspectives (Vol. 118, Issue 4) Peer-Reviewed

  Apr. 2010991 words Editorial 1670LComplex diseases have both genetic and environmental components. Understanding the contribution of environmental factors to disease susceptibility will require a more comprehensive view of exposure and biological...

• Theodora (Theo) Colborn 1927-2014

  Authors:Elizabeth Grossman, Laura N. Vandenberg, Kristina Thayer, and Linda S. BirnbaumFrom:Environmental Health Perspectives (Vol. 123, Issue 3) Peer-Reviewed

  Mar. 20151,029 words In memoriam 1480LTheodora Colborn, research scientist and environmental activist, died 14 December 2014 at the age of 87. As the scientist who coined the term "endocrine disruptor," Theo--as we had the privilege to call her--played a...

• Toxicological function of adipose tissue: focus on persistent organic pollutants

  Authors:Michele La Merrill, Claude Emond, Min Ji Kim, Jean-Philippe Antignac, Bruno Le Bizec, Karine Clement, et al.From:Environmental Health Perspectives (Vol. 121, Issue 2) Peer-Reviewed

  Feb. 20139,448 words Report 1380LObesity is increasing in developed countries and is a commonly known risk for disorders such as impaired glucose tolerance, metabolic syndrome, diabetes mellitus, liver and cardiovascular disease (CVD), and cancer...

• Consortium-based science: the NIEHS's multipronged, collaborative approach to assessing the health effects of bisphenol A

  Authors:Linda S. Birnbaum, John R. Bucher, Gwen W. Collman, Darryl C. Zeldin, Anne F. Johnson, Thaddeus T. Schug, et al.From:Environmental Health Perspectives (Vol. 120, Issue 12) Peer-Reviewed

  Dec. 20125,538 words Report 1490LBisphenol A (BPA) is used to produce polycarbonate plastics, epoxy resins, and other products. Manufacturers produce > 8 billion pounds of BPA every year, making it one of the most common industrial chemicals produced...

• Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice

  Authors:Michele La Merrill, Rachel Harper, Linda S. Birnbaum, Robert D. Cardiff, and David W. ThreadgillFrom:Environmental Health Perspectives (Vol. 118, Issue 5) Peer-Reviewed

  May 20106,367 words Report 1450LBACKGROUND: Results from previous studies have suggested that breast cancer risk correlates with total lifetime exposure to estrogens and that early-life 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure or diets high...

• Predictors of serum chlorinated pesticide concentrations among prepubertal Russian boys

  Authors:Thuy Lam, Paige L. Williams, Jane S. Burns, Oleg Sergeyev, Susan A. Korrick, Mary M. Lee, et al.From:Environmental Health Perspectives (Vol. 121, Issue 11-12) Peer-Reviewed

  November-December 20135,645 words Report 1380LBACKGROUND: Few studies have evaluated predictors of childhood exposure to organochlorine pesticides (OCPs), a class of lipophilic persistent chemicals. OBJECTIVES: Our goal was to identify predictors of serum OCP...

• Exposure assessment for endocrine disruptors: some considerations in the design of studies

  Authors:Carol Rice, Linda S. Birnbaum, James Cogliano, Kathryn Mahaffey, Larry Needham, Walter J. Rogan, et al.From:Environmental Health Perspectives (Vol. 111, Issue 13) Peer-Reviewed

  Oct. 20038,752 words Article In studies designed to evaluate exposure--response relationships in children's development from conception through puberty, multiple factors that affect the generation of meaningful exposure metrics must be considered....

• ONE Nano: NIEHS's Strategic Initiative on the health and safety effects of engineered nanomaterials

  Authors:Thaddeus T. Schug, Anne F. Johnson, David M. Balshaw, Stavros Garantziotis, Nigel J. Walker, Christopher Weis, et al.From:Environmental Health Perspectives (Vol. 121, Issue 4) Peer-Reviewed

  Apr. 20135,632 words Report 1550LBACKGROUND: The past decade has seen tremendous expansion in the production and application of engineered nanomaterials (ENMs). The unique properties that make ENMs useful in the marketplace also make their interactions...

• Applying research to public health questions: timing and the environmentally relevant dose

  Author:Linda S. BirnbaumFrom:Environmental Health Perspectives (Vol. 117, Issue 11) Peer-Reviewed

  Nov. 20091,014 words Editorial 1520LThe mission of National Institute of Environmental Health Sciences (NIEHS) is to improve the health of the American people by understanding the role of environmental exposures in disease and dysfunction. We accomplish...

• Marking a new understanding of climate and health

  Authors:Linda S. Birnbaum, John M. Balbus, and Kimberly Thigpen TartFrom:Environmental Health Perspectives (Vol. 124, Issue 4) Peer-Reviewed

  Apr. 2016841 words Editorial 1590LThe month of April brings two observances of significance for many readers of EHP: National Public Health Week and Earth Day. The first recognizes the importance of prevention efforts in maintaining the health of our...

• Moving NIEHS Forward for the Next Five Years

  Author:Linda S. BirnbaumFrom:Environmental Health Perspectives (Vol. 126, Issue 9) Peer-Reviewed

  Sept. 20181,160 words Editorial 1500LThis month, the National Institute of Environmental Health Sciences (NIEHS) is happy to announce its new Strategic Plan. NIEHS Strategic Plan 2018--2023: Advancing Environmental Health Science, Improving Health...

• Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat

  Authors:Michele La Merrill, David S. Baston, Michael S. Denison, Linda S. Birnbaum, Daniel Pomp, and David W. ThreadgillFrom:American Journal of Physiology (Consolidated) (Vol. 296, Issue 1) Peer-Reviewed

  Jan. 2009257 words Author abstract, Rep...

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• Dietary exposure to PCBs and dioxins in children

  Authors:Linda S. Birnbaum, Brian Slezak, Harma J. Albering, Edwin J.C. Moonen, Jurian A. Hoogewerff, and Jos C.S. KleinjansFrom:Environmental Health Perspectives (Vol. 107, Issue 1) Peer-Reviewed

  Jan. 199983 words Article

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• Bisphenol A, bisphenol S, and 4-hydroxyphenyl 4-isoprooxyphenylsulfone (BPSIP) in urine and blood of cashiers

  Authors:Kristina A. Thayer, Kyla W. Taylor, Stavros Garantziotis, Shepherd H. Schurman, Grace E. Kissling, Dawn Hunt, et al.From:Environmental Health Perspectives (Vol. 124, Issue 4) Peer-Reviewed

  Apr. 20167,986 words Report 1410LBackground: Bisphenol A (BPA) is a high-production-volume chemical associated with a wide range of health outcomes in animal and human studies. BPA is used as a developer in thermal paper products, including cash...

• Identifying Cost Savings Associated with NIEHS-Funded Research

  Author:Linda S. BirnbaumFrom:Environmental Health Perspectives (Vol. 126, Issue 6) Peer-Reviewed

  June 2018621 words Editorial 1520LThe National Institute of Environmental Health Sciences (NIEHS) has made great strides in identifying the benefits of reducing environmental contaminants and understanding how the environment affects health and disease....