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    Academic Journals

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• Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma.

  Authors:Xiaomo Jiang, Huai-Xiang Hao, Joseph D. Growney, Steve Woolfenden, Cindy Bottiglio, Nicholas Ng, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 110, Issue 31) Peer-Reviewed

  July 30, 2013246 words Report, Author abstr...

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• Prediction of central nervous system embryonal tumour outcome based on gene expression

  Authors:Scott L. Pomeroy, Pablo Tamayo, Michelle Gaasenbeek, Lisa M. Sturla, Michael Angelo, Margaret E. McLaughlin, et al.From:Nature (Vol. 415, Issue 6870) Peer-Reviewed

  Jan. 24, 20024,734 words Article 1560LAuthor(s): Scott L. Pomeroy (corresponding author) [1]; Pablo Tamayo [2]; Michelle Gaasenbeek [2]; Lisa M. Sturla [1]; Michael Angelo [2]; Margaret E. McLaughlin [3]; John Y. H. Kim [1, 4]; Liliana C. Goumnerova [5];...

• A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer.

  Authors:Michael Herfs, Yusuke Yamamoto, Anna Laury, Xia Wang, Marisa R. Nucci, Margaret E. McLaughlin-Drubin, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 109, Issue 26) Peer-Reviewed

  June 26, 2012232 words Clinical report, Aut...

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• Ocular melanoma

  Authors:Nora V. Laver, Margaret E. McLaughlin, and Jay S. DukerFrom:Archives of Pathology & Laboratory Medicine (Vol. 134, Issue 12) Peer-Reviewed

  Dec. 20105,207 words Disease/Disorder ove... 1740L* Context.--Intraocular melanoma of the ciliary body and choroid is the most common primary ocular malignant tumor in adults and the most common noncutaneous melanoma. Objective.--To describe the most salient...

• High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

  Authors:Hui Gao, Joshua M Korn, Stephane Ferretti, John E Monahan, Youzhen Wang, Mallika Singh, et al.From:Nature Medicine (Vol. 21, Issue 11) Peer-Reviewed

  Nov. 201510,227 words Article 1540LProfiling candidate therapeutics with limited cancer models during preclinical development hinders predictions of clinical efficacy and identifying factors that underlie heterogeneous patient responses for...

• Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers.

  Authors:Gregory R. Hoffman, Rami Rahal, Frank Buxton, Kay Xiang, Gregory McAllister, Elizabeth Frias, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 111, Issue 8) Peer-Reviewed

  Feb. 25, 2014214 words Report, Author abstr...

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• Restoration of p53 function leads to tumour regression in vivo

  Authors:Andrea Ventura, David G. Kirsch, Margaret E. McLaughlin, David A. Tuveson, Jan Grimm, Laura Lintault, et al.From:Nature (Vol. 445, Issue 7128) Peer-Reviewed

  Feb. 8, 20074,198 words Article 1460LAuthor(s): Andrea Ventura [1, 5]; David G. Kirsch [1, 2, 5]; Margaret E. McLaughlin [1]; David A. Tuveson [1]; Jan Grimm [3]; Laura Lintault [1]; Jamie Newman [1]; Elizabeth E. Reczek [1]; Ralph Weissleder [3]; Tyler...

• The Nf2 tumor suppressor regulates cell--cell adhesion during tissue fusion

  Authors:Margaret E. McLaughlin, Genevieve M. Kruger, Kelly L. Slocum, Denise Crowley, Norman A. Michaud, Jennifer Huang, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 104, Issue 9) Peer-Reviewed

  Feb. 27, 2007159 words Author abstract, Rep... 60L

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• Mouse Models of Tumor Development in Neurofibromatosis Type 1

  Authors:Karen Cichowski, T. Shane Shih, Earlene Schmitt, Sabrina Santiago, Karlyne Reilly, Margaret E. McLaughlin, et al.From:Science (Vol. 286, Issue 5447) Peer-Reviewed

  Dec. 10, 19992,982 words Article Neurofibromatosis type 1 (NF1) is a prevalent familial cancer syndrome resulting from germ line mutations in the NF1 tumor suppressor gene. Hallmark features of the disease are the development of benign peripheral nerve...

• Mutation spectrum of the gene encoding the beta subunit of rod phosphodiesterase among patients with autosomal recessive retinitis pigmentosa

  Authors:Margaret E. McLaughlin, Traci L. Ehrhart, Eliot L. Berson, and Thaddeus P. DryjaFrom:Proceedings of the National Academy of Sciences of the United States (Vol. 92, Issue 8) Peer-Reviewed

  Apr. 11, 199572 words Article

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• Cell type-specific effects of Rb deletion in the murine retina

  Authors:David MacPherson, Julien Sage, Teresa Kim, Dennis Ho, Margaret E. McLaughlin, and Tyler JacksFrom:Genes & Development (Vol. 18, Issue 14) Peer-Reviewed

  July 15, 200460 words Article

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• TATA-dependent and TATA-independent transcription at the HIS4 gene of yeast

  Authors:David Pellman, Margaret E. McLaughlin, and Gerald R. FinkFrom:Nature (Vol. 348, Issue 6296) Peer-Reviewed

  Nov. 1, 1990 Article

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• Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/[beta]-catenin signaling.

  Authors:Alix Scholer-Dahirel, Michael R. Schlabach, Alice Loo, Linda Bagdasarian, Ronald Meyer, Ribo Guo, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 108, Issue 41) Peer-Reviewed

  Oct. 11, 2011207 words Report, Author abstr...

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• Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming.

  Authors:Margaret E. McLaughlin-Drubin, Christopher P. Crum, and Karl MungerFrom:Proceedings of the National Academy of Sciences of the United States (Vol. 108, Issue 5) Peer-Reviewed

  Feb. 1, 2011168 words Report, Author abstr...

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• Ocular findings in spinocerebellar ataxia 7. (Clinicopathologic Reports, Case Reports, And Small Case Series)

  Authors:Margaret E. McLaughlin and Thaddeus P. DryjaFrom:Archives of Ophthalmology (Vol. 120, Issue 5) Peer-Reviewed

  May 2002 Article

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• Ocular pathologic findings of neurofibromatosis type 2

  Authors:Margaret E. McLaughlin, Susan M. Pepin, Mia MacCollin, Pitipol Choopong, and Simmons LessellFrom:Archives of Ophthalmology (Vol. 125, Issue 3) Peer-Reviewed

  Mar. 2007 Article

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• APC-mediated proteolysis of ase1 and the morphogenesis of the mitotic spindle

  Authors:Yue-Li Juang, James Huang, Jan-Michael Peters, Margaret E. McLaughlin, Chin-Yin Tai, and David PellmanFrom:Science (Vol. 275, Issue 5304) Peer-Reviewed

  Feb. 28, 19972,546 words Article The molecular mechanisms that link cell-cycle controls to the mitotic apparatus are poorly understood. A component of the Saccharomyces cerevisiae spindle, Ase1, was observed to undergo cell cycle-specific degradation...

• Automated Biochemical, Morphological, and Organizational Assessment of Precancerous Changes from Endogenous Two-Photon Fluorescence Images

  Authors:Jonathan M. Levitt, Margaret E. McLaughlin-Drubin, Karl Munger, and Irene GeorgakoudiFrom:PLoS ONE (Vol. 6, Issue 9) Peer-Reviewed

  Sept. 9, 20118,469 words Article 1650LBackground Multi-photon fluorescence microscopy techniques allow for non-invasive interrogation of live samples in their native environment. These methods are particularly appealing for identifying pre-cancers...

• Tumor suppressor [p16.sup.INK4A] is necessary for survival of cervical carcinoma cell lines.

  Authors:Margaret E. McLaughlin-Drubin, Donglim Park, and Karl MungerFrom:Proceedings of the National Academy of Sciences of the United States (Vol. 110, Issue 40) Peer-Reviewed

  Oct. 1, 2013199 words Report, Author abstr...

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