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From:PLoS ONE (Vol. 6, Issue 4) Peer-ReviewedThe protein ataxin-3 consists of an N-terminal globular Josephin domain (JD) and an unstructured C-terminal region containing a stretch of consecutive glutamines that triggers the neurodegenerative disorder...
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From:PLoS ONE (Vol. 8, Issue 3) Peer-ReviewedAuthor(s): Alessandra Apicella 1 , 2 , Monica Soncini 3 , * , Marco Agostino Deriu 4 , Antonino Natalello 5 , Marcella Bonanomi 5 , David Dellasega 1 , Paolo Tortora 5 , Maria Elena Regonesi 6 , * , Carlo Spartaco...
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From:PLoS ONE (Vol. 10, Issue 6) Peer-ReviewedAtaxin-3 (AT3) is a deubiquitinating enzyme that triggers an inherited neurodegenerative disorder, spinocerebellar ataxia type 3, when its polyglutamine (polyQ) stretch close to the C-terminus exceeds a critical length....
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From:BioMed Research InternationalPeer-ReviewedGlobe artichoke is an intriguing source of indigestible sugar polymers such as inulin-type fructans. In this study, the effect of ultrasound in combination with ethanol precipitation to enhance the extraction of long...