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From:PLoS ONE (Vol. 17, Issue 6) Peer-ReviewedBackground PR interval prolongation is a preliminary stage of atrial cardiomyopathy which is considered as an intermediate phenotype for atrial fibrillation (AF). AF is a known risk factor for cerebrovascular adverse...
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From:Alzheimer's Research & Therapy (Vol. 14, Issue 1) Peer-ReviewedImportance The entry of artificial intelligence into medicine is pending. Several methods have been used for the predictions of structured neuroimaging data, yet nobody compared them in this context. Objective...
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From:PLoS ONE (Vol. 8, Issue 2) Peer-ReviewedIntroduction We aimed at dissociating the neural correlates of memory disorders in Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD). Methods We included patients with AD (n = 19, 11 female,...
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From:PLoS ONE (Vol. 6, Issue 4) Peer-ReviewedSeveral studies have shown that obesity is associated with changes in human brain function and structure. Since women are more susceptible to obesity than men, it seems plausible that neural correlates may also be...
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From:PLoS ONE (Vol. 8, Issue 2) Peer-ReviewedAuthor(s): Juergen Dukart 1 , 3 , * , Robert Perneczky 6 , 8 , 12 , Stefan Förster 9 , Henryk Barthel 4 , 7 , Janine Diehl-Schmid 6 , 8 , Bogdan Draganski 1 , 5 , Hellmuth Obrig 2 , 3 , Emiliano Santarnecchi 10 ,...
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From:PLoS ONE (Vol. 6, Issue 7) Peer-ReviewedIn recent research, many univariate and multivariate approaches have been proposed to improve automatic classification of various dementia syndromes using imaging data. Some of these methods do not provide the...
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From:PLoS ONE (Vol. 9, Issue 12) Peer-ReviewedObesity is known to affect the brain's gray matter (GM) and white matter (WM) structure but the interrelationship of such changes remains unclear. Here we used T1-weighted magnetic resonance imaging (MRI) in combination...
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From:Alzheimer's Research & Therapy (Vol. 10, Issue 1) Peer-ReviewedBackground With upcoming therapeutic interventions for patients with primary progressive aphasia (PPA), instruments for the follow-up of patients are needed to describe disease progression and to evaluate potential...
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From:PLoS ONE (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Stefan Holiga 1 , * , Harald E. Möller 1 , Tomás Sieger 2 , 3 , Matthias L. Schroeter 1 , 4 , Robert Jech 2 , Karsten Mueller 1 Introduction Parkinson's disease (PD) is a progressive neurodegenerative...
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From:PLoS ONE (Vol. 7, Issue 8) Peer-ReviewedAuthor(s): Daniel-Paolo Streitbürger 1 , * , Harald E. Möller 1 , Marc Tittgemeyer 2 , Margret Hund-Georgiadis 1 , Matthias L. Schroeter 1 , 3 , Karsten Mueller 1 Introduction A number of recent studies employing...
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From:PLoS ONE (Vol. 7, Issue 8) Peer-ReviewedIntroduction Former studies have investigated the potential of serum biomarkers for diseases affecting the human brain. In particular the glial protein S100B, a neuro- and gliotrophin inducing plasticity, seems to be...
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From:PLoS ONE (Vol. 13, Issue 5) Peer-ReviewedInformation on circulating miRNAs in frontotemporal lobar degeneration is very limited and conflicting results have complicated an interpretation in Alzheimer's disease thus far. In the present study we I) collected...
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From:PLoS ONE (Vol. 8, Issue 2) Peer-ReviewedTo tackle the heterogeneity of Parkinson's disease symptoms, most functional imaging studies tend to select a uniform group of subjects. We hypothesize that more profound considerations are needed to account for...
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From:PLoS ONE (Vol. 6, Issue 3) Peer-ReviewedIntroduction Various biomarkers have been reported in recent literature regarding imaging abnormalities in different types of dementia. These biomarkers have helped to significantly improve early detection and also...
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From:Health Psychology (Vol. 37, Issue 2) Peer-Reviewed
APOE e4-genotype and lifestyle interaction on cognitive performance: Results of the LIFE-Adult-study
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