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    Academic Journals

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• Glucocorticoid exposure of sheep at 0.7 to 0.75 gestation augments late-gestation fetal stress responses

  Authors:Matthias Schwab, Turhan Coksaygan, Florian Rakers, and Peter W. NathanielszFrom:American Journal of Obstetrics and Gynecology (Vol. 206, Issue 3) Peer-Reviewed

  Mar. 2012 Report

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• The authors' reply

  Author:Matthias SchwabFrom:Clinical Pharmacokinetics (Vol. 46, Issue 9) Peer-Reviewed

  Sept. 2007539 words Letter to the editor 2130LWe appreciate the interest that Gardiner et al. took in our recent article on thiopurine treatment in inflammatory bowel disease. [1] Importantly, the incidence of inflammatory bowel disease peaks during the...

• Electrocortical and heart rate response during vibroacoustic stimulation in fetal sheep

  Authors:Reinhard Bauer, Matthias Schwab, Robert M. Abrams, Jana Stein, and Kenneth J. GerhardtFrom:American Journal of Obstetrics and Gynecology (Vol. 177, Issue 1) Peer-Reviewed

  July 1997318 words Report

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• Development of human membrane transporters: drug disposition and pharmacogenetics

  Authors:Miriam G. Mooij, Anne T. Nies, Catherijne A. J. Knibbe, Elke Schaeffeler, Dick Tibboel, Matthias Schwab, et al.From:Clinical Pharmacokinetics (Vol. 55, Issue 5) Peer-Reviewed

  May 2016 Report

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• Thiopurine treatment in inflammatory bowel disease: clinical pharmacology and implication of pharmacogenetically guided dosing

  Authors:Alexander Teml, Elke Schaeffeler, Klaus R. Herrlinger, Ulrich Klotz, and Matthias SchwabFrom:Clinical Pharmacokinetics (Vol. 46, Issue 3) Peer-Reviewed

  Mar. 200713,025 words Article 2090LThis review summarises clinical pharmacological aspects of thiopurines in the treatment of chronic inflammatory bowel disease (IBD). Current knowledge of pharmacogenetically guided dosing is discussed for...

• Prenatal undernutrition and leukocyte telomere length in late adulthood: the Dutch famine birth cohort study

  Authors:Susanne R. de Rooij, Ans M.M. van Pelt, Susan E. Ozanne, Cindy M. Korver, Saskia K.M. van Daalen, Rebecca C. Painter, et al.From:American Journal of Clinical Nutrition (Vol. 102, Issue 3) Peer-Reviewed

  Sept. 2015273 words Author abstract, Rep...

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• Intestinal absorption, metabolism, and excretion of (-)-epicatechin in healthy humans assessed by using an intestinal perfusion technique

  Authors:Lucas Actis-Goretta, Antoine Leveques, Maarit Rein, Alexander Teml, Christian Schafer, Ute Hofmann, et al.From:American Journal of Clinical Nutrition (Vol. 98, Issue 4) Peer-Reviewed

  Oct. 2013251 words Author abstract

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• Vulnerability of the fetal primate brain to moderate reduction in maternal global nutrient availability

  Authors:Iwa Antonow-Schlorke, Matthias Schwab, Laura A. Cox, Cun Li, Kristina Stuchlik, Otto W. Witte, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 108, Issue 7) Peer-Reviewed

  Feb. 15, 2011143 words Author abstract, Rep...

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• Impact of metabolizing enzymes on drug response of endocrine therapy in breast cancer

  Authors:Pilar H Saladores, Jana C Precht, Werner Schroth, Hiltrud Brauch, and Matthias SchwabFrom:Expert Review of Molecular Diagnostics (Vol. 13, Issue 4) Peer-Reviewed

  May 201312,858 words Report 1460LAuthor(s): Pilar H Saladores [[double dagger]] 1 , Jana C Precht [[double dagger]] 1 , Werner Schroth 1 , Hiltrud Brauch 1 , Matthias Schwab [*] 2 Keywords : anastrozole; aromatase inhibitors; CYP2D6; endocrine...

• Reduced Paneth cell [alpha]-defensins in ileal Crohn's disease

  Authors:Jan Wehkamp, Nita H. Salzman, Edith Porter, Sabine Nuding, Michael Weichenthal, Robert E. Petras, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 102, Issue 50) Peer-Reviewed

  Dec. 13, 2005217 words Author abstract

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• Frequency of C3435T polymorphism of MDR1 gene in African people

  Authors:Elke Schaeffeler, Michel Eichelbaum, Ulrich Brinkmann, Anja Penger, Steven Asante-Poku, Ulrich M Zanger, et al.From:The Lancet (Vol. 358, Issue 9279) Peer-Reviewed

  Aug. 4, 2001230 words Article

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• Population pharmacokinetics of the BEACOPP polychemotherapy regimen in Hodgkin's lymphoma and its effect on myelotoxicity

  Authors:Stefan Wilde, Alexander Jetter, Stephan Rietbrock, Dirk Kasel, Andreas Engert, Andreas Josting, et al.From:Clinical Pharmacokinetics (Vol. 46, Issue 4) Peer-Reviewed

  Apr. 20077,145 words Article Background and objective: The BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine and prednisone) chemotherapy regimen for the treatment of advanced Hodgkin's lymphoma has a superior...

• Selective Protection of Human Liver Tissue in TNF-Targeting of Cancers of the Liver by Transient Depletion of Adenosine Triphosphate

  Authors:Timo Weiland, Kathrin Klein, Martina Zimmermann, Tobias Speicher, Sascha Venturelli, Alexander Berger, et al.From:PLoS ONE (Vol. 7, Issue 12) Peer-Reviewed

  Dec. 18, 20125,370 words Article 1620LBackground Tumor necrosis factor alpha (TNF) is able to kill cancer cells via receptor-mediated cell death requiring adenosine triphosphate (ATP). Clinical usage of TNF so far is largely limited by its profound...

• CYP2C19 and nongenetic factors predict poor responsiveness to clopidogrel loading dose after coronary stent implantation

  Authors:Tobias Geisler, Elke Schaeffeler, Juergen Dippon, Stefan Winter, Verena Buse, Christian Bischofs, et al.From:Pharmacogenomics (Vol. 9, Issue 9) Peer-Reviewed

  Sept. 20085,152 words Article Author(s): Tobias Geisler 1 , Elke Schaeffeler 2 , Juergen Dippon 3 , Stefan Winter 4 , Verena Buse 4 , Christian Bischofs 4 , Christine Zuern 4 , Klaus Moerike 4 , Meinrad Gawaz 4 , Matthias Schwab [[dagger]] 4...

• Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response

  Authors:Jan-Patrick Stellmann, Markus Krumbholz, Tim Friede, Anna Gahlen, Nadja Borisow, Katrin Fischer, et al.From:Journal of Neurology, Neurosurgery and Psychiatry (Vol. 88, Issue 8) Peer-Reviewed

  Aug. 2017 Report

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• Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects

  Authors:Arian Emami Riedmaier, Pascale Fisel, Anne T. Nies, Elke Schaeffeler, and Matthias SchwabFrom:Trends in Pharmacological Sciences (Vol. 34, Issue 2) Peer-Reviewed

  Feb. 2013231 words Report

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• ABCC11/MRP8 polymorphisms affect 5-fluorouracil-induced severe toxicity and hepatic expression

  Authors:Tarek Magdy, Rudolf Arlanov, Stefan Winter, Thomas Lang, Kathrin Klein, Yu Toyoda, et al.From:Pharmacogenomics (Vol. 14, Issue 12) Peer-Reviewed

  Sept. 20138,588 words Report 1470LAuthor(s): Tarek Magdy 1 , Rudolf Arlanov 1 , Stefan Winter 1 , Thomas Lang 1 , Kathrin Klein 1 , Yu Toyoda 2 , Toshihisa Ishikawa 3 , Matthias Schwab 1 4 , Ulrich M Zanger [*] 5 KEYWORDS : 5-fluorouracil;...

• Clinical pharmacokinetics and use of infliximab

  Authors:Ulrich Klotz, Alexander Teml, and Matthias SchwabFrom:Clinical Pharmacokinetics (Vol. 46, Issue 8) Peer-Reviewed

  Aug. 20078,914 words Article 2070LTumor necrosis factor-[alpha] (TNF[alpha]) is a key proinflammatory cytokine involved in chronic inflammatory diseases. Infliximab, a chimeric (human-murine) monoclonal IgGl anti-TNF[alpha] antibody, is used in the...

• Genetic Variants of Wnt Transcription Factor TCF-4 (TCF7L2) Putative Promoter Region Are Associated with Small Intestinal Crohn's Disease

  Authors:Maureen J. Koslowski, Irmgard Kubler, Mathias Chamaillard, Elke Schaeffeler, Walter Reinisch, Guoxing Wang, et al.From:PLoS ONE (Vol. 4, Issue 2) Peer-Reviewed

  Feb. 16, 20096,261 words Article 1580LReduced expression of Paneth cell antimicrobial [alpha]-defensins, human defensin (HD)-5 and -6, characterizes Crohn's disease (CD) of the ileum. TCF-4 (also named TCF7L2), a Wnt signalling pathway transcription factor,...

• Frequency of C3435T polymorphism of MDR1 gene in African people

  Authors:Elke Schaeffeler, Michel Eichelbaum, Ulrich Brinkmann, Anja Penger, Steven Asante-Poku, Ulrich M Zanger, et al.From:The Lancet (Vol. 358, Issue 9279) Peer-Reviewed

  Aug. 4, 2001 Brief article

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