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    Academic Journals

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• When good drugs go bad

  Authors:Kathleen M. Giacomini, Ronald M. Krauss, Dan M. Roden, Michel Eichelbaum, Michael R. Hayden, and Yusuke NakamuraFrom:Nature (Vol. 446, Issue 7139) Peer-Reviewed

  Apr. 26, 20072,506 words Article 1440LAuthor(s): Kathleen M. Giacomini [1]; Ronald M. Krauss [2]; Dan M. Roden [3]; Michel Eichelbaum [4]; Michael R. Hayden [5]; Yusuke Nakamura [6] [illus. 1] Safety issues can arise throughout the life-history of a drug...

• Intestinal absorption, metabolism, and excretion of (-)-epicatechin in healthy humans assessed by using an intestinal perfusion technique

  Authors:Lucas Actis-Goretta, Antoine Leveques, Maarit Rein, Alexander Teml, Christian Schafer, Ute Hofmann, et al.From:American Journal of Clinical Nutrition (Vol. 98, Issue 4) Peer-Reviewed

  Oct. 2013251 words Author abstract

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• Frequency of C3435T polymorphism of MDR1 gene in African people

  Authors:Elke Schaeffeler, Michel Eichelbaum, Ulrich Brinkmann, Anja Penger, Steven Asante-Poku, Ulrich M Zanger, et al.From:The Lancet (Vol. 358, Issue 9279) Peer-Reviewed

  Aug. 4, 2001230 words Article

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• CYP3A genetics in drug metabolism

  Authors:Michel Eichelbaum and Oliver BurkFrom:Nature Medicine (Vol. 7, Issue 3) Peer-Reviewed

  Mar. 20011,509 words Article Author(s): Michel Eichelbaum [1]; Oliver Burk [2] All living organisms, including humans, are continuously exposed to approximately 10,000 chemicals present in food, drinks and the environment. Many naturally...

• Pharmacogenomics and individualized drug therapy

  Authors:Michel Eichelbaum, Magnus Ingelman-Sundberg, and William E. EvansFrom:Annual Review of Medicine (Vol. 57) Peer-Reviewed

  Annual 200648 words Article

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• Frequency of C3435T polymorphism of MDR1 gene in African people

  Authors:Elke Schaeffeler, Michel Eichelbaum, Ulrich Brinkmann, Anja Penger, Steven Asante-Poku, Ulrich M Zanger, et al.From:The Lancet (Vol. 358, Issue 9279) Peer-Reviewed

  Aug. 4, 2001 Brief article

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• Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms of efavirenz pharmacokinetics and treatment response: an AIDS clinical trials group study

  Authors:Heather J. Ribaudo, Huan Liu, Matthias Schwab, Elke Schaeffeler, Michel Eichelbaum, Alison A. Motsinger-Reit, et al.From:Journal of Infectious Diseases (Vol. 202, Issue 5) Peer-Reviewed

  Sept. 1, 2010 Clinical report

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• Automated extraction of DNA and RNA from a single formalin-fixed paraffin-embedded tissue section for analysis of both single-nucleotide polymorphisms and mRNA expression

  Authors:Guido Hennig, Mathias Gehrmann, Udo Stropp, Hiltrud Brauch, Peter Fritz, Michel Eichelbaum, et al.From:Clinical Chemistry (Vol. 56, Issue 12) Peer-Reviewed

  Dec. 20104,969 words Article 1660L

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• Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux

  Authors:Svitlana Igel, Siegfried Drescher, Thomas Murdter, Ute Hofmann, Georg Heinkele, Heike Tegude, et al.From:Clinical Pharmacokinetics (Vol. 46, Issue 9) Peer-Reviewed

  Sept. 20074,449 words Article Background and objectives: The contribution of transport in the small intestine by the apically located efflux pump P-glycoprotein to variable drug absorption in humans is still poorly understood. We therefore...

• Identification of the primary gene defect at the cytochrome P450 CYP2D6 locus

  Authors:Alan C. Gough, John S. Miles, Nigel K. Spurr, Julie E. Moss, Andrea Gaedigk, Michel Eichelbaum, et al.From:Nature (Vol. 347, Issue 6295) Peer-Reviewed

  Oct. 25, 1990 Article

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• Frequency of C3435T polymorphism of MDR1 gene in African people

  Authors:Elke Schaeffeler, Michel Eichelbaum, Ulrich Brinkmann, Anja Penger, Steven Asante-Poku, Ulrich M. Zanger, et al.From:The Lancet (Vol. 358, Issue 9279) Peer-Reviewed

  Aug. 4, 2001197 words Article

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• High-throughput genotyping of thiopurine S-methyltransferase by denaturing HPLC

  Authors:Elke Schaeffeler, Thomas Lang, Ulrich M. Zanger, Michel Eichelbaum, and Matthias SchwabFrom:Clinical Chemistry (Vol. 47, Issue 3) Peer-Reviewed

  Mar. 20014,824 words Article 1480L

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• Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen

  Authors:Werner Schroth, Matthew P. Goetz, Ute Hamann, Peter A. Fasching, Marcus Schmidt, Stefan Winter, et al.From:JAMA, The Journal of the American Medical Association (Vol. 302, Issue 13) Peer-Reviewed

  Oct. 7, 200942 words Clinical report

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• Using trade names: a risk factor for accidental drug overdose. (Clinical Observation)

  Authors:Matthias Schwab, Carsten Oetzel, Klaus Morike, Christine Jagle, Christoph H. Gleiter, and Michel EichelbaumFrom:Archives of Internal Medicine (Vol. 162, Issue 9) Peer-Reviewed

  May 13, 200260 words Article

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• Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia

  Authors:Martin Stanulla, Thomas Flohr, Elke Schaeffeler, Gunnar Cario, Wof-Dieter Ludwig, Andre Schrauder, et al.From:JAMA, The Journal of the American Medical Association (Vol. 293, Issue 12) Peer-Reviewed

  Mar. 23, 200554 words Article

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• Pharmacogenomics of tamoxifen therapy

  Authors:Hiltrud Brauch, Thomas E. Murdter, Michel Eichelbaum, and Matthias SchwabFrom:Clinical Chemistry (Vol. 55, Issue 10) Peer-Reviewed

  Oct. 20099,599 words Article 1590L

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• MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms

  Authors:Julia K. Blievernicht, Elke Schaeffeler, Kathrin Klein, Michel Eichelbaum, Matthias Schwab, and Ulrich M. ZangerFrom:Clinical Chemistry (Vol. 53, Issue 1) Peer-Reviewed

  Jan. 20075,231 words Article 1490L

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