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Academic Journals
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From:Proceedings of the National Academy of Sciences of the United States (Vol. 118, Issue 34) Peer-ReviewedAbstract Only
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From:Journal of Immunology Research (Vol. 2019) Peer-ReviewedBackground. Unbiased studies using different genome-wide methods have identified a great number of candidate biomarkers for diagnosis and treatment response in pediatric ulcerative colitis (UC). However, clinical...
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From:PLoS ONE (Vol. 7, Issue 6) Peer-ReviewedAuthor(s): Yelin Zhao 1 , Hui Wang 1 , 2 , Mika Gustafsson 1 , Antonella Muraro 3 , Sören Bruhn 1 , Mikael Benson 1 , * Introduction Seasonal allergic rhinitis (SAR) is a common airway disease, which is caused by...
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From:PLoS ONE (Vol. 8, Issue 7) Peer-ReviewedAuthor(s): Gabriel Skogberg 1,*, Judith Gudmundsdottir 1,2, Sjoerd van der Post 3, Kerstin Sandström 4, Sören Bruhn 5, Mikael Benson 5,6, Lucia Mincheva-Nilsson 7, Vladimir Baranov 7, Esbjörn Telemo 1, Olov Ekwall 1,2...
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From:Journal of Immunology Research (Vol. 2017) Peer-ReviewedSpecific immunotherapy (SIT) reverses the symptoms of seasonal allergic rhinitis (SAR) in most patients. Recent studies report type I interferons shifting the balance between type IT helper cell (Th1) and type II T...
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From:PLoS ONE (Vol. 6, Issue 8) Peer-ReviewedBackground Glucocorticoids (GCs) play a key role in the treatment of seasonal allergic rhinitis (SAR). However, some patients show a low response to GC treatment. We hypothesized that proteins that correlated to...
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From:PLoS ONE (Vol. 4, Issue 11) Peer-Reviewed
Network Properties of Complex Human Disease Genes Identified through Genome-Wide Association Studies
Author(s): Fredrik Barrenas 1,*, Sreenivas Chavali 1, Petter Holme 2,3, Reza Mobini 1, Mikael Benson 1 Introduction Systems Biology based approaches of studying human genetic diseases have brought in a shift in... -
From:PLoS ONE (Vol. 8, Issue 10) Peer-ReviewedAllergy is a complex disease that is likely to involve dysregulated CD4+ T cell activation. Here we propose a novel methodology to gain insight into how coordinated behaviour emerges between disease-dysregulated...